Efficient induction of apoptosis in HeLa cells by a novel cationic porphycene photosensitizer

European Journal of Medicinal Chemistry

Volumn 63, Issue , 2013, Pages 401-414

  Ruiz González, Rubén ^a   Acedo, Pilar ^b   Sánchez García, David ^a   Nonell, Santi ^a   Cañete, Magdalena ^b   Stockert, Juan Carlos ^b   Villanueva, Angeles ^b  

^a INSTITUT QUÍMIC DE SARRIÀ   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Apoptosis; Cationic photosensitizer; HeLa cells; Necrosis; Photodynamic therapy; Singlet oxygen

Indexed keywords

2,7,12 TRIS(ALPHA PYRIDINIO 4 TOLYL) 17 [4 (METHOXYMETHYL)PHENYL]PORPHYCENE; ACTIN; CYTOCHROME C; PHOTOSENSITIZING AGENT; PORPHYCENE; PROTEIN BAX; SINGLET OXYGEN; SODIUM AZIDE; TRYPSIN; UNCLASSIFIED DRUG; VINCULIN;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL DEATH; CELL GRANULE; CELL KILLING; CELL LOSS; CELL PROTECTION; CELL STRUCTURE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; CYTOSKELETON; CYTOSOL; CYTOTOXICITY; ENZYME RELEASE; FLOW CYTOMETRY; FLUORESCENCE; HELA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INCUBATION TIME; IRRADIATION; MICROFILAMENT; MICROTUBULE; MITOCHONDRION; MOLECULAR PROBE; NECROSIS; NICK END LABELING; PHOTOBIOLOGY; PHOTODYNAMIC THERAPY; PHOTOINACTIVATION; PHOTOSENSITIZATION; PHOTOTOXICITY; RADIATION EXPOSURE; TUMOR CELL CULTURE; ULTRAVIOLET RADIATION;

APOPTOSIS; CATIONS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; FLOW CYTOMETRY; HELA CELLS; HUMANS; LIGHT; MICROSCOPY, FLUORESCENCE; MOLECULAR STRUCTURE; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYRINS;

EID: 84875023525     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.02.028     Document Type: Article

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