A requirement for bid for induction of apoptosis by photodynamic therapy with a lysosome- but not a mitochondrion-targeted photosensitizer

Photochemistry and Photobiology

Volumn 86, Issue 5, 2010, Pages 1161-1173

  Chiu, Song Mao ^a   Xue, Liang Yan ^a   Lam, Minh ^a,b   Rodriguez, Myriam E ^a   Zhang, Ping ^b   Kenney, Malcolm E ^b   Nieminen, Anna Liisa ^c   Oleinick, Nancy L ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BID PROTEIN, HUMAN; LYSOZYME; PHOTOSENSITIZING AGENT; PROTEIN BID;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CHEMICAL STRUCTURE; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFECT; GENE INACTIVATION; GENETICS; MITOCHONDRION; PHOTOCHEMOTHERAPY; PHYSIOLOGY; RADIATION EXPOSURE; WESTERN BLOTTING;

APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BLOTTING, WESTERN; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; GENE KNOCKOUT TECHNIQUES; MITOCHONDRIA; MOLECULAR STRUCTURE; MURAMIDASE; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS;

MURINAE;

EID: 77956481608     PISSN: 00318655     EISSN: 17511097     Source Type: Journal    
DOI: 10.1111/j.1751-1097.2010.00766.x     Document Type: Article

References (30)

1. Moan, J. K. Berg (1992) Photochemotherapy of cancer: Experimental research. Photochem. Photobiol. 55, 931 948.
2. Weishaupt, K. R., C. J. Gomer T. J. Dougherty (1976) Identification of singlet oxygen as the cytotoxic agent in photoinactivation of a murine tumor. Cancer Res. 36, 2326 2329.
3. Peng, Q., J. Moan J. M. Nesland (1996) Correlation of subcellular and intratumoral photosensitizer localization with ultrastructural features after photodynamic therapy. Ultrastruct. Pathol. 20, 109 129.
4. Oleinick, N. L., R. L. Morris I. Belichenko (2002) The role of apoptosis in response to photodynamic therapy: What, where, why, and how. Photochem. Photobiol. Sci. 1, 1 21.
5. Kessel, D. (2006) Death pathways associated with photodynamic therapy. Med. Laser Appl. 21, 219 224.
6. Kessel, D., Y. Luo, P. Mathieu J. J. Reiners Jr. (2000) Determinants of the apoptotic response to lysosomal photodamage. Photochem. Photobiol. 71, 196 200.
7. Reiners, J. J., Jr., J. A. Caruso, P. Mathieu, B. Chelladurai, X. M. Yin D. Kessel (2002) Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves Bid cleavage. Cell Death Differ. 9, 934 944.
8. Gross, A., J. M. McDonnell S. J. Korsmeyer (1999) BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 13, 1899 1911.
9. Wang, K., X. M. Yin, D. T. Chao, C. L. Milliman S. J. Korsmeyer (1996) BID: A novel BH3 domain-only death agonist. Genes Dev. 10, 2859 2869.
10. Shimizu, S. Y. Tsujimoto (2000) Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity. Proc. Natl Acad. Sci. USA, 97, 577 582.
11. Stoka, V., B. Turk, S. L. Schendel, T. H. Kim, T. Cirman, S. J. Snipas, L. M. Ellerby, D. Bredesen, H. Freeze, M. Abrahamson, D. Bromme, S. Krajewski, J. C. Reed, X. M. Yin, V. Turk G. S. Salvesen (2001) Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route. J. Biol. Chem. 276, 3149 3157.
12. Ichinose, S., J. Usuda, T. Hirata, T. Inoue, K. Ohtani, S. Maehara, M. Kubota, K. Imai, Y. Tsunoda, Y. Kuroiwa, K. Yamada, H. Tsutsui, K. Furukawa, T. Okunaka, N. L. Oleinick H. Kato (2006) Lysosomal cathepsin initiates apoptosis, which is regulated by photodamage to Bcl-2 at mitochondria in photodynamic therapy using a novel photosensitizer, ATX-s10 (Na). Int. J. Oncol. 29, 349 355.
13. Wan, Q., L. Liu, D. Xing Q. Chen (2008) Bid is required in NPe6-PDT-induced apoptosis. Photochem. Photobiol. 84, 250 257.
14. Rodriguez, M. E., P. Zhang, K. Azizuddin, G. B. D. Santos, S. Chiu, L. Xue, J. C. Berlin, X. Peng, H. Wu, M. Lam, A. Nieminen, M. E. Kenney N. L. Oleinick (2009) Structural factors and mechanisms underlying the improved photodynamic cell killing with silicon phthalocyanine photosensitizers directed to lysomes versus mitochondria. Photochem. Photobiol. 85, 1189 1200.
15. Chiu, S. M. N. L. Oleinick (2001) Dissociation of mitochondrial depolarization from cytochrome c release during apoptosis induced by photodynamic therapy. Br. J. Cancer 84, 1099 1106.
16. Xue, L. Y., S. M. Chiu N. L. Oleinick (2001) Photodynamic therapy-induced death of MCF-7 human breast cancer cells: A role for caspase-3 in the late steps of apoptosis but not for the critical lethal event. Exp. Cell Res. 263, 145 155.
17. Chiu, S., H. H. Evans, M. Lam, A. Nieminen N. L. Oleinick (2001) Phthalocyanine 4 photodynamic therapy-induced apoptosis of mouse L5178Y-R cells results from a delayed but extensive release of cytochrome c from mitochondria. Cancer Lett. 165, 51 58.
18. Trivedi, N.S. (2000) Quantitative analysis of Pc 4 localization in mouse lymphoma (LY-R) cells via double-label confocal fluorescence microscopy. Photochem. Photobiol. 71, 634 639.
19. Lam, M., N. L. Oleinick A. L. Nieminen (2001) Photodynamic therapy-induced apoptosis in epidermoid carcinoma cells. Reactive oxygen species and mitochondrial inner membrane permeabilization. J. Biol. Chem. 276, 47379 47386.
20. Usuda, J., S. M. Chiu, E. S. Murphy, M. Lam, A. L. Nieminen N. L. Oleinick (2003) Domain-dependent photodamage to Bcl-2. A membrane anchorage region is needed to form the target of phthalocyanine photosensitization. J. Biol. Chem. 278, 2021 2029.
21. Chiu, S. M., L. Y. Xue, J. Usuda, K. Azizuddin N. L. Oleinick (2003) Bax is essential for mitochondrion-mediated apoptosis but not for cell death caused by photodynamic therapy. Br. J. Cancer 89, 1590 1597.
22. Xue, L. Y., S. M. Chiu N. L. Oleinick (2003) Staurosporine-induced death of MCF-7 human breast cancer cells: A distinction between caspase-3-dependent steps of apoptosis and the critical lethal lesions. Exp. Cell Res. 283, 135 145.
23. Li, H., H. Zhu, C. J. Xu J. Yuan (1998) Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94, 491 501.
24. Cirman, T., K. Oresic, G. D. Mazovec, V. Turk, J. C. Reed, R. M. Myers, G. S. Salvesen B. Turk (2004) Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins. J. Biol. Chem. 279, 3578 3587.
25. Varnes, M. E., S. M. Chiu, L. Y. Xue N. L. Oleinick (1999) Photodynamic therapy-induced apoptosis in lymphoma cells: Translocation of cytochrome c causes inhibition of respiration as well as caspase activation. Biochem. Biophys. Res. Commun. 255, 673 679.
26. Caruso, J. A., P. A. Mathieu, A. Joiakim, B. Leeson, D. Kessel, B. F. Sloane J. J. Reiners Jr. (2004) Differential susceptibilities of murine hepatoma 1c1c7 and Tao cells to the lysosomal photosensitizer NPe6: Influence of aryl hydrocarbon receptor on lysosomal fragility and protease contents. Mol. Pharmacol. 65, 1016 1028.
27. DeDuve, C. (1983) Lysosomes revisited. Eur. J. Biochem. 137, 391 397.
28. Levine, B. D. J. Klionsky (2004) Development by self-digestion: Molecular mechanisms and biological functions of autophagy. Dev. Cell 6, 463 477.
29. Fehrenbacher, N. M. Jaattela (2005) Lysosomes as targets for cancer therapy. Cancer Res. 65, 2993 2995.
30. Jaattela, M., C. Cande G. Kroemer (2004) Lysosomes and mitochondria in the commitment to apoptosis: A potential role for cathepsin D and AIF. Cell Death Differ. 11, 135 136.