The E. coli Effector Protein NleF Is a Caspase Inhibitor

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Blasche, Sonja ^a   Mörtl, Mario ^b   Steuber, Holger ^b,h   Siszler, Gabriella ^a   Nisa, Shahista ^c   Schwarz, Frank ^a   Lavrik, Inna ^a,i   Gronewold, Thomas M A ^e   Maskos, Klaus ^b   Donnenberg, Michael S ^c   Ullmann, Dirk ^b   Uetz, Peter ^d,g   Kögl, Manfred ^a,f  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b PROTEROS BIOSTRUCTURES GMBH   (Germany)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^e SAW Instruments GmbH   (Germany)

^f BOEHRINGER INGELHEIM RCV GMBH AND CO KG   (Austria)

^g EVOTEC AG   (Germany)

^h PHILIPPS UNIVERSITY MARBURG   (Germany)

ⁱ OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 4; CASPASE 7; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; EFFECTOR PROTEIN NLED; EFFECTOR PROTEIN NLEF; EFFECTOR PROTEIN NLEH; LIPOCORTIN 5; PROTEIN A; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BIOLOGICAL MODEL; CARBOXY TERMINAL SEQUENCE; CELL ASSAY; CELL STRAIN CACO 2; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYSTAL STRUCTURE; ENTEROPATHOGENIC ESCHERICHIA COLI; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME INHIBITION; HELA CELL; HUMAN; IN VITRO STUDY; NONHUMAN; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION; TWO HYBRID SYSTEM; VALIDATION PROCESS;

CASPASE INHIBITORS; CASPASES; CELL LINE; ESCHERICHIA COLI O157; ESCHERICHIA COLI PROTEINS; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; REPRODUCIBILITY OF RESULTS; VIRULENCE FACTORS;

EID: 84875022980     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058937     Document Type: Article

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