-
1
-
-
38349169664
-
Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
-
Filipowicz W, Bhattacharyya S N, Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight? Nat Rev Genet, 2008, 9: 102-114.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 102-114
-
-
Filipowicz, W.1
Bhattacharyya, S.N.2
Sonenberg, N.3
-
3
-
-
34249819336
-
MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals
-
Tsang J, Zhu J, van Oudenaarden A. MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Mol Cell, 2007, 26: 753-767.
-
(2007)
Mol Cell
, vol.26
, pp. 753-767
-
-
Tsang, J.1
Zhu, J.2
van Oudenaarden, A.3
-
4
-
-
84860324470
-
Roles for microRNAs in conferring robustness to biological processes
-
Ebert M S, Sharp P A. Roles for microRNAs in conferring robustness to biological processes. Cell, 2012, 149: 515-524.
-
(2012)
Cell
, vol.149
, pp. 515-524
-
-
Ebert, M.S.1
Sharp, P.A.2
-
6
-
-
29244437908
-
The role of double-strand break repair-Insights from human genetics
-
O'Driscoll M, Jeggo P A. The role of double-strand break repair-Insights from human genetics. Nat Rev Genet, 2006, 7: 45-54.
-
(2006)
Nat Rev Genet
, vol.7
, pp. 45-54
-
-
O'Driscoll, M.1
Jeggo, P.A.2
-
7
-
-
38049150586
-
The DNA damage response pathways: At the crossroad of protein modifications
-
Huen M S, Chen J. The DNA damage response pathways: At the crossroad of protein modifications. Cell Res, 2008, 18: 8-16.
-
(2008)
Cell Res
, vol.18
, pp. 8-16
-
-
Huen, M.S.1
Chen, J.2
-
8
-
-
33645814188
-
p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene
-
Arias-Lopez C, Lazaro-Trueba I, Kerr P, et al. p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene. EMBO Rep, 2006, 7: 219-224.
-
(2006)
EMBO Rep
, vol.7
, pp. 219-224
-
-
Arias-Lopez, C.1
Lazaro-Trueba, I.2
Kerr, P.3
-
9
-
-
34047112221
-
Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia
-
Bindra R S, Glazer P M. Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia. Oncogene, 2007, 26: 2048-2057.
-
(2007)
Oncogene
, vol.26
, pp. 2048-2057
-
-
Bindra, R.S.1
Glazer, P.M.2
-
10
-
-
34547766645
-
ZNF143 interacts with p73 and is involved in cisplatin resistance through the transcriptional regulation of DNA repair genes
-
Wakasugi T, Izumi H, Uchiumi T, et al. ZNF143 interacts with p73 and is involved in cisplatin resistance through the transcriptional regulation of DNA repair genes. Oncogene, 2007, 26: 5194-5203.
-
(2007)
Oncogene
, vol.26
, pp. 5194-5203
-
-
Wakasugi, T.1
Izumi, H.2
Uchiumi, T.3
-
11
-
-
33749000596
-
The role of BRCA1 in transcriptional regulation and cell cycle control
-
Mullan P B, Quinn J E, Harkin D P. The role of BRCA1 in transcriptional regulation and cell cycle control. Oncogene, 2006, 25: 5854-5863.
-
(2006)
Oncogene
, vol.25
, pp. 5854-5863
-
-
Mullan, P.B.1
Quinn, J.E.2
Harkin, D.P.3
-
12
-
-
66149157349
-
MiR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells
-
Lal A, Pan Y, Navarro F, et al. MiR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells. Nat Struct Mol Biol, 2009, 16: 492-498.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 492-498
-
-
Lal, A.1
Pan, Y.2
Navarro, F.3
-
13
-
-
39149116326
-
AsSIRTing the DNA damage response
-
Gorospe M, de Cabo R. AsSIRTing the DNA damage response. Trends Cell Biol, 2008, 18: 77-83.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 77-83
-
-
Gorospe, M.1
de Cabo, R.2
-
14
-
-
33847647624
-
SIRT1 promotes DNA repair activity and deacetylation of Ku70
-
Jeong J, Juhn K, Lee H, et al. SIRT1 promotes DNA repair activity and deacetylation of Ku70. Exp Mol Med, 2007, 39: 8-13.
-
(2007)
Exp Mol Med
, vol.39
, pp. 8-13
-
-
Jeong, J.1
Juhn, K.2
Lee, H.3
-
15
-
-
53149137486
-
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
-
Wang R H, Sengupta K, Li C, et al. Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell, 2008, 14: 312-323.
-
(2008)
Cancer Cell
, vol.14
, pp. 312-323
-
-
Wang, R.H.1
Sengupta, K.2
Li, C.3
-
16
-
-
56749156405
-
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
Oberdoerffer P, Michan S, McVay M, et al. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell, 2008, 135: 907-918.
-
(2008)
Cell
, vol.135
, pp. 907-918
-
-
Oberdoerffer, P.1
Michan, S.2
McVay, M.3
-
17
-
-
34250378403
-
A protocol for rapid generation of recombinant adenoviruses using the AdEasy system
-
Luo J, Deng Z L, Luo X, et al. A protocol for rapid generation of recombinant adenoviruses using the AdEasy system. Nat Protoc, 2007, 2: 1236-1247.
-
(2007)
Nat Protoc
, vol.2
, pp. 1236-1247
-
-
Luo, J.1
Deng, Z.L.2
Luo, X.3
-
18
-
-
34250654965
-
The comet assay: A method to measure DNA damage in individual cells
-
Olive P L, Banath J P. The comet assay: A method to measure DNA damage in individual cells. Nat Protoc, 2006, 1: 23-29.
-
(2006)
Nat Protoc
, vol.1
, pp. 23-29
-
-
Olive, P.L.1
Banath, J.P.2
-
19
-
-
3042681042
-
SIRT1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma
-
Picard F, Kurtev M, Chung N, et al. SIRT1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature, 2004, 429: 771-776.
-
(2004)
Nature
, vol.429
, pp. 771-776
-
-
Picard, F.1
Kurtev, M.2
Chung, N.3
-
20
-
-
0347063999
-
Retrovirus vector-mediated stable gene silencing in human cell
-
Liu C M, Liu D P, Dong W J, et al. Retrovirus vector-mediated stable gene silencing in human cell. Biochem Biophys Res Commun, 2004, 313: 716-720.
-
(2004)
Biochem Biophys Res Commun
, vol.313
, pp. 716-720
-
-
Liu, C.M.1
Liu, D.P.2
Dong, W.J.3
-
21
-
-
29144470346
-
Real-time quantification of microRNAs by stem-loop RT-PCR
-
Chen C, Ridzon D A, Broomer A J, et al. Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res, 2005, 33: e179.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Chen, C.1
Ridzon, D.A.2
Broomer, A.J.3
-
22
-
-
34547458550
-
p53-mediated activation of miRNA34 candidate tumor-suppressor genes
-
Bommer G T, Gerin I, Feng Y, et al. p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol, 2007, 17: 1298-1307.
-
(2007)
Curr Biol
, vol.17
, pp. 1298-1307
-
-
Bommer, G.T.1
Gerin, I.2
Feng, Y.3
-
23
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
He L, He X, Lim L P, et al. A microRNA component of the p53 tumour suppressor network. Nature, 2007, 447: 1130-1134.
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
-
24
-
-
34249812122
-
MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells
-
Welch C, Chen Y, Stallings R L. MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene, 2007, 26: 5017-5022.
-
(2007)
Oncogene
, vol.26
, pp. 5017-5022
-
-
Welch, C.1
Chen, Y.2
Stallings, R.L.3
-
25
-
-
34249817549
-
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
-
Chang T C, Wentzel EA, Kent O A, et al. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell, 2007, 26: 745-752.
-
(2007)
Mol Cell
, vol.26
, pp. 745-752
-
-
Chang, T.C.1
Wentzel, E.A.2
Kent, O.A.3
-
26
-
-
34249822779
-
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
-
Raver-Shapira N, Marciano E, Meiri E, et al. Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol Cell, 2007, 26: 731-743.
-
(2007)
Mol Cell
, vol.26
, pp. 731-743
-
-
Raver-Shapira, N.1
Marciano, E.2
Meiri, E.3
-
27
-
-
34848868157
-
Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
-
Tazawa H, Tsuchiya N, Izumiya M, et al. Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc Natl Acad Sci USA, 2007, 104: 15472-15477.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15472-15477
-
-
Tazawa, H.1
Tsuchiya, N.2
Izumiya, M.3
-
28
-
-
0033569684
-
XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
-
Pierce A J, Johnson R D, Thompson L H, et al. XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev, 1999, 13: 2633-2638.
-
(1999)
Genes Dev
, vol.13
, pp. 2633-2638
-
-
Pierce, A.J.1
Johnson, R.D.2
Thompson, L.H.3
-
29
-
-
54449092239
-
Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells
-
Fujita Y, Kojima K, Hamada N, et al. Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells. Biochem Biophys Res Commun, 2008, 377: 114-119.
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 114-119
-
-
Fujita, Y.1
Kojima, K.2
Hamada, N.3
-
31
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis B P, Burge C B, Bartel D P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell, 2005, 120: 15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
32
-
-
77949653651
-
Role of SIRT1 in homologous recombination
-
Uhl M, Csernok A, Aydin S, et al. Role of SIRT1 in homologous recombination. DNA Repair (Amst), 2010, 9: 383-393.
-
(2010)
DNA Repair (Amst)
, vol.9
, pp. 383-393
-
-
Uhl, M.1
Csernok, A.2
Aydin, S.3
-
33
-
-
0033554592
-
Dissociation of the recombination control and the sequence-specific transactivation function of p53
-
Dudenhoffer C, Kurth M, Janus F, et al. Dissociation of the recombination control and the sequence-specific transactivation function of p53. Oncogene, 1999, 18: 5773-5784.
-
(1999)
Oncogene
, vol.18
, pp. 5773-5784
-
-
Dudenhoffer, C.1
Kurth, M.2
Janus, F.3
-
34
-
-
0034598771
-
Dissociation of p53-mediated suppression of homologous recombination from G1/S cell cycle checkpoint control
-
Willers H, McCarthy E E, Wu B, et al. Dissociation of p53-mediated suppression of homologous recombination from G1/S cell cycle checkpoint control. Oncogene, 2000, 19: 632-639.
-
(2000)
Oncogene
, vol.19
, pp. 632-639
-
-
Willers, H.1
McCarthy, E.E.2
Wu, B.3
-
35
-
-
11244344381
-
P53: Traffic cop at the crossroads of DNA repair and recombination
-
Sengupta S, Harris C C. P53: Traffic cop at the crossroads of DNA repair and recombination. Nat Rev Mol Cell Biol, 2005, 6: 44-55.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 44-55
-
-
Sengupta, S.1
Harris, C.C.2
|