Prevalence of antifolate resistance mutations in Plasmodium falciparum isolates in Afghanistan

Malaria Journal

Volumn 12, Issue 1, 2013, Pages

  Awab, Ghulam R ^a,c   Pukrittayakamee, Sasithon ^b   Jamornthanyawat, Natsuda ^b   Yamin, Fazel ^c   Dondorp, Arjen M ^a,d   Day, Nicholas Pj ^a,d   White, Nicholas J ^a,d   Woodrow, Charles J ^a,d   Imwong, Mallika ^b  

^a MAHIDOL OXFORD TROPICAL MEDICINE RESEARCH UNIT   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c Ministry of Public Health   (Afghanistan)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Artemisinin combination therapy; Dihydrofolate reductase; Dihydropteroate synthase; Malaria; Plasmodium falciparum; Sulphadoxine pyrimethamine

Indexed keywords

ARTESUNATE; DIHYDROARTEMISININ PLUS PIPERAQUINE; PYRIMETHAMINE PLUS SULFADOXINE;

AFGHANISTAN; ANTIMALARIAL DRUG RESISTANCE; ARTICLE; GENE DOSAGE; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; NONHUMAN; PLASMODIUM FALCIPARUM; PREVALENCE;

ADULT; AFGHANISTAN; ANTIMALARIALS; ARTEMISININS; CHILD; CHILD, PRESCHOOL; DNA, PROTOZOAN; DRUG COMBINATIONS; DRUG RESISTANCE; FOLIC ACID ANTAGONISTS; HUMANS; MALARIA, FALCIPARUM; MUTATION, MISSENSE; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PREVALENCE; PROTOZOAN PROTEINS; PYRIMETHAMINE; SULFADOXINE;

EID: 84874943027     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-12-96     Document Type: Article

References (29)

1. Malaria sentinel surveillance in Afghanistan. Leslie T, Mohammed N, Omar H, Rasheed HU, Vorst F, Sediqi AM, Afghanistan Annual Malaria Journal 2008 114 128
2. A new world malaria map: Plasmodium falciparum endemicity in 2010. Gething PW, Patil AP, Smith DL, Guerra CA, Elyazar IR, Johnston GL, Tatem AJ, Hay SI, Malar J 2011 10 378 10.1186/1475-2875-10-378 22185615
3. WHO, Afghanistan country profile 2011 http://www.who.int/malaria/ publications/country-profiles/profile-afg-en.pdf
4. The first case of Plasmodium falciparum resistant to chloroquine treatment discovered in the Republic of Afghanistan. Delfini LF, Trans R Soc Trop Med Hyg 1989 83 316 10.1016/0035-9203(89)90486-0 2694464 (Pubitemid 19163213)
5. Efficacy of combination therapy with artesunate plus amodiaquine compared to monotherapy with chloroquine, amodiaquine or sulfadoxine-pyrimethamine for treatment of uncomplicated Plasmodium falciparum in Afghanistan. Durrani N, Leslie T, Rahim S, Graham K, Ahmad F, Rowland M, Trop Med Int Health 2005 10 521 529 10.1111/j.1365-3156.2005.01429.x 15941414 (Pubitemid 40806657)
6. Sulfadoxine-pyrimethamine remains efficacious against uncomplicated, Plasmodium falciparum malaria in north-eastern Afghanistan. Ezard N, Nellepalli P, Asha AW, Ann Trop Med Parasitol 2004 98 85 88 10.1179/000349804225003019 15000735 (Pubitemid 38210469)
7. Defining Plasmodium falciparum treatment in South West Asia: a randomized trial comparing artesunate or primaquine combined with chloroquine or SP. Kolaczinski K, Leslie T, Ali I, Durrani N, Lee S, Barends M, Beshir K, Ord R, Hallett R, Rowland M, PLoS One 2012 7 28957 10.1371/journal.pone.0028957 22303437
8. Genotypes and in vivo resistance of Plasmodium falciparum isolates in an endemic region of Iran. Heidari A, Dittrich S, Jelinek T, Kheirandish A, Banihashemi K, Keshavarz H, Parasitol Res 2007 100 589 592 17024359 (Pubitemid 46011271)
9. Mechanisms of resistance of malaria parasites to antifolates. Gregson A, Plowe CV, Pharmacol Rev 2005 57 117 145 10.1124/pr.57.1.4 15734729 (Pubitemid 40283971)
10. Monitoring and deterring drug-resistant malaria in the era of combination therapy. Laufer MK, Djimde AA, Plowe CV, Am J Trop Med Hyg 2007 77 160 169 18165489
11. Plasmodium falciparum: detection of polymorphisms in the dihydrofolate reductase and dihydropteroate synthetase genes by PCR and restriction digestion. Duraisingh MT, Curtis J, Warhurst DC, Exp Parasitol 1998 89 1 8 10.1006/expr.1998.4274 9603482 (Pubitemid 28377366)
12. The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin. Duraisingh MT, Jones P, Sambou I, von Seidlein L, Pinder M, Warhurst DC, Mol Biochem Parasitol 2000 108 13 23 10.1016/S0166-6851(00)00201-2 10802315 (Pubitemid 30236312)
13. Assessment of pfmdr 1 gene copy number by tandem competitive polymerase chain reaction. Price R, Robinson G, Brockman A, Cowman A, Krishna S, Mol Biochem Parasitol 1997 85 161 169 10.1016/S0166-6851(96)02822-8 9106190 (Pubitemid 27170215)
14. Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment. Carrara VI, Zwang J, Ashley EA, Price RN, Stepniewska K, Barends M, Brockman A, Anderson T, McGready R, Phaiphun L, Proux S, van Vugt M, Hutagalung R, Lwin KM, Phyo AP, Preechapornkul P, Imwong M, Pukrittayakamee S, Singhasivanon P, White NJ, Nosten F, PLoS One 2009 4 4551 10.1371/journal.pone.0004551 19234601
15. Origin and evolution of sulfadoxine resistant Plasmodium falciparum. Vinayak S, Alam MT, Mixson-Hayden T, McCollum AM, Sem R, Shah NK, Lim P, Muth S, Rogers WO, Fandeur T, Barnwell JW, Escalante AA, Wongsrichanalai C, Ariey F, Meshnick SR, Udhayakumar V, PLoS Pathog 2010 6 1000830 10.1371/journal.ppat. 1000830 20360965
16. Multiple origins of Plasmodium falciparum dihydropteroate synthetase mutant alleles associated with sulfadoxine resistance in India. Lumb V, Das MK, Singh N, Dev V, Khan W, Sharma YD, Antimicrob Agents Chemother 2011 55 2813 2817 10.1128/AAC.01151-10 21422213
17. Amodiaquine resistance in Plasmodium falciparum malaria in Afghanistan is associated with the pfcrt SVMNT allele at codons 72 to 76. Beshir K, Sutherland CJ, Merinopoulos I, Durrani N, Leslie T, Rowland M, Hallett RL, Antimicrob Agents Chemother 2010 54 3714 3716 10.1128/AAC.00358-10 20547800
18. Prevalence of resistance associated polymorphisms in Plasmodium falciparum field isolates from southern Pakistan. Ghanchi NK, Ursing J, Beg MA, Veiga MI, Jafri S, Martensson A, Malar J 2011 10 18 10.1186/1475-2875-10-18 21272384
19. Prevalence of antimalarial drug resistance mutations in Plasmodium vivax and P. falciparum from a malaria-endemic area of Pakistan. Khatoon L, Baliraine FN, Bonizzoni M, Malik SA, Yan G, Am J Trop Med Hyg 2009 81 525 528 19706926
20. Prevalence of mutations associated with antimalarial drugs in Plasmodium falciparum isolates prior to the introduction of sulphadoxine-pyrimethamine as first-line treatment in Iran. Zakeri S, Afsharpad M, Raeisi A, Djadid ND, Malar J 2007 6 148 10.1186/1475-2875-6-148 17999755 (Pubitemid 351169901)
21. High prevalence of double Plasmodium falciparum dhfr mutations at codons 108 and 59 in the Sistan-Baluchistan province, Iran. Zakeri S, Gil JP, Bereckzy S, Djadid ND, Bjorkman A, J Infect Dis 2003 187 1828 1829 10.1086/375250 12751044 (Pubitemid 36667897)
22. High prevalence of the 437 G mutation associated with sulfadoxine resistance among Plasmodium falciparum clinical isolates from Iran, three years after the introduction of sulfadoxine-pyrimethamine. Zakeri S, Farahani MS, Afsharpad M, Salehi M, Raeisi A, Djadid ND, Int J Infect Dis 2010 14 Suppl 3 123 e128 20399698
23. Molecular monitoring of Plasmodium falciparum resistance to antimalarial drugs after adoption of sulfadoxine-pyrimethamine plus artesunate as the first line treatment in Iran. Afsharpad M, Zakeri S, Pirahmadi S, Djadid ND, Acta Trop 2012 121 13 18 10.1016/j.actatropica.2011.09.010 22001304
24. Molecular survey of Plasmodium falciparum resistance in south-eastern Iran. Jafari S, Le Bras J, Asmar M, Durand R, Ann Trop Med Parasitol 2003 97 119 124 10.1179/000349803235001552 12803866 (Pubitemid 36543232)
25. Novel point mutations in sulfadoxine resistance genes of Plasmodium falciparum from India. Garg S, Saxena V, Kanchan S, Sharma P, Mahajan S, Kochar D, Das A, Acta Trop 2009 110 75 79 10.1016/j.actatropica.2009.01.009 19283899
26. Plasmodium falciparum isolates in India exhibit a progressive increase in mutations associated with sulfadoxine-pyrimethamine resistance. Ahmed A, Bararia D, Vinayak S, Yameen M, Biswas S, Dev V, Kumar A, Ansari MA, Sharma YD, Antimicrob Agents Chemother 2004 48 879 889 10.1128/AAC.48.3.879-889.2004 14982779 (Pubitemid 38280339)
27. Overdiagnosis and mistreatment of malaria among febrile patients at primary healthcare level in Afghanistan: observational study. Leslie T, Mikhail A, Mayan I, Anwar M, Bakhtash S, Nader M, Chandler C, Whitty CJ, Rowland M, BMJ 2012 345 4389 10.1136/bmj.e4389 22833603
28. Effects of artesunate-mefloquine combination on incidence of Plasmodium falciparum malaria and mefloquine resistance in western Thailand: a prospective study. Nosten F, van Vugt M, Price R, Luxemburger C, Thway KL, Brockman A, McGready R, ter Kuile F, Looareesuwan S, White NJ, Lancet 2000 356 297 302 10.1016/S0140-6736(00)02505-8 11071185 (Pubitemid 30459588)
29. Antimalarial drug resistance. White NJ, J Clin Invest 2004 113 1084 1092 15085184 (Pubitemid 38544090)