Genotypes and in vivo resistance of Plasmodium falciparum isolates in an endemic region of Iran

Parasitology Research

Volumn 100, Issue 3, 2007, Pages 589-592

  Heidari, Aliehsan ^a,d   Dittrich, Sabine ^b   Jelinek, Tomas ^b   Kheirandish, Azarmidokht ^c   Banihashemi, Kambiz ^d   Keshavarz, Hossein ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b Institute of Tropical Medicine   (Germany)

^c Beheshti University   (Iran)

^d AEROSPACE RESEARCH INSTITUTE   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ARGININE; ASPARAGINE; DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; FANSIDAR; FOLIC ACID ANTAGONIST; MOLECULAR MARKER; PHENYLALANINE;

ADOLESCENT; ADULT; ARTICLE; CHILD; CODON; CONTROLLED STUDY; DRUG EFFICACY; DRUG TREATMENT FAILURE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENE MUTATION; GENOTYPE; HUMAN; IRAN; MAJOR CLINICAL STUDY; MUTATIONAL ANALYSIS; NONHUMAN; OLIGONUCLEOTIDE PROBE; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; ANIMALS; ANTIMALARIALS; CHILD; CHILD, PRESCHOOL; DIHYDROPTEROATE SYNTHASE; DRUG RESISTANCE; GENOTYPE; HUMANS; IRAN; MALARIA, FALCIPARUM; MIDDLE AGED; MUTATION; PARASITEMIA; PLASMODIUM FALCIPARUM; TETRAHYDROFOLATE DEHYDROGENASE;

PLASMODIUM FALCIPARUM;

EID: 33845753891     PISSN: 09320113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00436-006-0291-z     Document Type: Article

References (15)

1. Abdel-Hameed AA (2003) Antimalarial drug resistance in the Eastern Mediterranean region. East Mediterr Health J 9(4):492-508
2. Alifrangis M, Enosse S (2005) A simple, high throughput method to detect Plasmodium falciparum single nucleotide polymorphisms in the dihydrofolate reductase, dihydropteroate syntase, and P. falciparum Chloroquine resistance transporter genes using polymerase chain reaction and Enzyme-linked immunosorbent Assay-based technology. Am J Trop Med Hyg 72(2):155-162
3. Berens N, Schwoebel B (2003) Plasmodium falciparum: correlation of in vivo resistance to chloroquine and antifolates with genetic polymorphisms in isolates from the south of Lao PDR. Trop Med Int Health 8(9):775-782
4. Berzosa PJ, Puente S (2005) Malaria cure with sulphadoxine/pyrimethamine combination in 12 semi-immune adults from West-central Africa with high rates of point mutation in Plasmodiumfalciparum dhfr and dhps genes. Parasitol Res 97 (4):287-289
5. Edrissian GH (1989) Status of the response of Plasmodium falciparum to Chloroquine in Iran. Trop Geogr Med 41(4):297-303
6. Edrissian GH, Afshar A (1993) Assessment of the response in vivo and in vitro of Plasmodium falciparum to sulphadoxine-pyrimethamine in the malarious areas of Iran. J Trop Med Hyg 96(4):237-240
7. Eskandarian AA, Keshavarz H (2002) Do mutations in Plasmodium-falciparum dihydropteroate synthase and dihydrofolate reductase confer resistance to sulfadoxine-pyrimethamine in Iran? Trans R Soc Trop Med Hyg 96(1):96-98
8. Happi CT, Gbotosho GO (2005) Polymorphisms in Plasmodiumfalciparumdhfr and dhps genes and age related in vivo sulfadoxine-pyrimethamine resistance in malaria-infected patients from Nigeria. Acta Trop 95(3):183-193
9. Jelinek T, Ronn AM (1998) Polymorphisms in the dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) genes of Plasmodium falciparum and in vivo resistance to sulphadoxine/pyrimethamine in isolates from Tanzania. Trop Med Int Health 3(8):605-608
10. Khan MA, Smego RA (2004) Emerging drug-resistance and guidelines for treatment of malaria. J Coll Physicians Surg Pak 14 (5):319-324
11. Kublin JG, Witzig RS (1998) Molecular assays for surveillance of antifolate-resistance malaria. Lancet 351:1629-1630
12. Rakhsani F, AnsariMoghadam AR (2003) Knowledge, perceptions and prevention of malaria among women in Sistan va Baluchestan, Islamic Republic of Iran. East Mediterr Health J 9(3):248-256
13. WHO (2005) The work of WHO in the Eastern Mediterranean region. Annual report of regional director. WHO Regional Office for the Eastern Mediterranean, Alexandria
14. WHO-CDS/RBM (2002) Monitoring antimalarial drug resistance - report of a WHO consultation, vol 39. WHO, Geneva
15. Zakeri S, Gil JP (2003) High prevalence of double Plasmodium falciparum dhfr mutation at codons 108 and 59 in the Sistan-Baluchistan province, Iran. J Infect Dis 187(11):1828-1829