Echinacea sanguinea and echinacea pallida extracts stimulate glucuronidation and basolateral transfer of bauer alkamides 8 and 10 and ketone 24 and inhibit p-glycoprotein transporter in caco-2 cells

Planta Medica

Volumn 79, Issue 3-4, 2013, Pages 266-274

  Qiang, Zhiyi ^a   Hauck, Cathy ^a   McCoy, Joe Ann ^a   Widrlechner, Mark P ^a   Reddy, Manju B ^a   Murphy, Patricia A ^a   Hendrich, Suzanne ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

alkamides; Caco 2 cells; Echinacea (Asteraceae); ketones; P glycoprotein; permeability

Indexed keywords

ALCOHOL; AMIDE; CALCEIN; CARRIER PROTEIN; ECHINACEA PALLIDA EXTRACT; ECHINACEA SANGUINEA EXTRACT; GLUCURONIDE; KETONE; P GLYCOPROTEIN TRANSPORTER; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DIFFUSION; DRUG GLUCURONIDATION; DRUG METABOLISM; DRUG PENETRATION; ECHINACEA PALLIDA; ECHINACEA SANGUINEA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROPHILICITY; INTESTINE EPITHELIUM CELL; MEDICINAL PLANT;

ALKYNES; CACO-2 CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; ECHINACEA; FLUORESCEINS; GLUCURONIDES; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; P-GLYCOPROTEIN; PERMEABILITY; PLANT EXTRACTS; PLANTS, MEDICINAL; POLYUNSATURATED ALKAMIDES;

ASTERACEAE; ECHINACEA (ASTERACEAE); ECHINACEA PALLIDA; ECHINACEA SANGUINEA;

EID: 84874938188     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0032-1328198     Document Type: Article

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