Permeability of rosmarinic acid in Prunella vulgaris and ursolic acid in Salvia officinalis extracts across Caco-2 cell monolayers

Journal of Ethnopharmacology

Volumn 137, Issue 3, 2011, Pages 1107-1112

  Qiang, Zhiyi ^a   Ye, Zhong ^b   Hauck, Cathy ^a   Murphy, Patricia A ^a   McCoy, Joe Ann ^c   Widrlechner, Mark P ^a,d   Reddy, Manju B ^a   Hendrich, Suzanne ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c North Carolina Arboretum   (United States)

^d AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

Caco 2; Permeability; Prunella vulgaris; Rosmarinic acid; Salvia officinalis; Ursolic acid

Indexed keywords

PRUNELLA VULGARIS EXTRACT; ROSMARINIC ACID; SALVIA OFFICINALIS EXTRACT; URSOLIC ACID;

ARTICLE; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DETERMINATION; DRUG PENETRATION; HUMAN; HUMAN CELL; LIMIT OF DETECTION;

BIOLOGICAL AVAILABILITY; BIOTRANSFORMATION; CACO-2 CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CINNAMATES; DEPSIDES; GASTROINTESTINAL AGENTS; GLUCURONIDASE; GLUCURONIDES; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; PERMEABILITY; PLANT EXTRACTS; PLANTS, MEDICINAL; PRUNELLA; SALVIA OFFICINALIS; SULFATASES; SULFURIC ACID ESTERS; TIME FACTORS; TRITERPENES;

PRUNELLA VULGARIS; SALVIA OFFICINALIS;

EID: 80054948721     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.07.037     Document Type: Article

References (32)

1. S. Baba, N. Osakabe, M. Natsume, and J. Terao Orally administered rosmarinic acid is present as the conjugated and/or methylated forms in plasma, and is degraded and metabolized to conjugated forms of caffeic acid, ferulic acid and m-coumaric acid Life Sciences 75 2004 165 178
2. S. Baba, N. Osakabe, M. Natsume, A. Yasuda, Y. Muto, K. Hiyoshi, H. Takano, T. Yoshikawa, and J. Terao Absorption, metabolism, degradation and urinary excretion of rosmarinic acid after intake of Perilla frutescens extract in humans European Journal of Nutrition 44 2005 1 9
3. C. Bérangre, N. Caussarieu, P. Morin, L. Morin-Allory, and M. Lafosse Rapid analysis of triterpenic acids by liquid chromatography using porous graphitic carbon and evaporative light scattering detection Journal of Separation Science 27 2004 964 970
4. G. Chen, E. Banoglu, and M.W. Duffel Influence of substrate structure on the catalytic efficiency of hydroxysteroid sulfotransferase STa in the sulfation of alcohols Chemical Research in Toxicology 9 1996 67 74
5. H.Y. Cheung, and Q.F. Zhang Enhanced analysis of triterpenes, flavonoids and phenolic compounds in Prunella vulgaris L. by capillary zone electrophoresis with the addition of running buffer modifiers Journal of Chromatography A 1213 2008 231 238
6. T. Ebner, and B. Burchell Substrate specificities of two stably expressed human liver UDP-glucuronosyltransferases of the UGT1 gene family Drug Metabolism and Disposition 21 1993 50 55
7. S. Gao, W. Jiang, T. Yin, and M. Hu Highly variable contents of phenolics in St. John's Wort products affect their transport in the human intestinal Caco-2 cell model: pharmaceutical and biopharmaceutical rationale for product standardization Journal of Agricultural and Food Chemistry 58 2010 6650 6659
8. I. Hubatsch, E.G. Ragnarsson, and P. Artursson Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers Nature Protocols 2 2007 2111 2119
9. S.M. Kern, R.N. Bennett, P.W. Needs, F.A. Mellon, P.A. Kroon, and M.T. Garcia-Conesa Characterization of metabolites of hydroxycinnamates in the in vitro model of human small intestinal epithelium caco-2 cells Journal of Agricultural and Food Chemistry 51 2003 7884 7891
10. Y. Konishi, and S. Kobayashi Transepithelial transport of chlorogenic acid, caffeic acid, and their colonic metabolites in intestinal caco-2 cell monolayers Journal of Agricultural and Food Chemistry 52 2004 2518 2526
11. Y. Konishi, Y. Hitomi, M. Yoshida, and E. Yoshioka Pharmacokinetic study of caffeic and rosmarinic acids in rats after oral administration Journal of Agricultural and Food Chemistry 53 2005 4740 4746
12. Y. Konishi, and S. Kobayashi Transepithelial transport of rosmarinic acid in intestinal Caco-2 cell monolayers Bioscience, Biotechnology, and Biochemistry 69 2005 583 591
13. Q. Liao, W. Yang, Y. Jia, X. Chen, Q. Gao, and K. Bi LC-MS determination and pharmacokinetic studies of ursolic acid in rat plasma after administration of the traditional Chinese medicinal preparation Lu-Ying extract Yakugaku Zasshi 125 2005 509 515
14. J. Liu Pharmacology of oleanolic acid and ursolic acid Journal of Ethnopharmacology 49 1995 57 68
15. M.R. Loizzo, A.M. Saab, R. Tundis, G.A. Statti, F. Menichini, I. Lampronti, R. Gambari, J. Cinatl, and H.W. Doerr Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species Chemistry and Biodiversity 5 2008 461 470
16. Y. Lu, and L.Y. Foo Flavonoid and phenolic glycosides from Salvia officinalis Phytochemistry 55 2000 263 267
17. T. Lu, J. Yang, X. Gao, P. Chen, F. Du, Y. Sun, F. Wang, F. Xu, H. Shang, Y. Huang, Y. Wang, R. Wan, C. Liu, B. Zhang, and C. Li Plasma and urinary tanshinol from Salvia miltiorrhiza (Danshen) can be used as pharmacokinetic markers for cardiotonic pills, a cardiovascular herbal medicine Drug Metabolism and Disposition 36 2008 1578 1586
18. C. Manach, A. Scalbert, C. Morand, C. Remesy, and L. Jimenez Polyphenols: food sources and bioavailability The American Journal of Clinical Nutrition 79 2004 727 747
19. J.T. Mukinda, J.A. Syce, D. Fisher, and M. Meyer Effect of the plant matrix on the uptake of luteolin derivatives-containing Artemisia afra aqueous-extract in Caco-2 cells Journal of Ethnopharmacology 130 2010 439 449
20. N. Nakagawa, M. Katoh, Y. Yoshioka, M. Nakajima, and T. Yokoi Inhibitory effects of Kampo medicine on human UGT2B7 activity Drug Metabolism and Pharmacokinetics 24 2009 490 499
21. B. Nasser, K. Moustaid, S. Moukha, T.A. Mobio, A. Essamadi, and E.E. Creppy Evaluation of the cytotoxicity and genotoxicity of extracts of mussels originating from Moroccan Atlantic coast, in human colonic epithelial cells Caco-2 Environmental Toxicology 23 2008 539 547
22. A.P. Neilson, J.C. George, E.M. Janle, R.D. Mattes, R. Rudolph, N.V. Matusheski, and M.G. Ferruzzi Influence of chocolate matrix composition on cocoa flavan-3-ol bioaccessibility in vitro and bioavailability in humans Journal of Agricultural and Food Chemistry 57 2009 9418 9426
23. A. Ohashi, M. Fukumuro, K. Sawabe, K. Mamada, Y. Sugawara, H. Matsuoka, and H. Hasegawa Transcellular relocation of tetrahydrobiopterin across Caco-2 cells: a model study of tetrahydrobiopterin absorption through epithelial cells of intestinal mucosa Journal of Inherited Metabolic Disease 32 2009 73 78
24. N. Osakabe, A. Yasuda, M. Natsume, C. Sanbongi, Y. Kato, T. Osawa, and T. Yoshikawa Rosmarinic acid, a major polyphenolic component of Perilla frutescens, reduces lipopolysaccharide (LPS)-induced liver injury in d-galactosamine (d-GalN)-sensitized mice Free Radical Biology and Medicine 33 2002 798 806
25. K.C. Peng, F. Cluzeaud, M. Bens, J.P. Duong Van Huyen, M.A. Wioland, R. Lacave, and A. Vandewalle Tissue and cell distribution of the multidrug resistance-associated protein (MRP) in mouse intestine and kidney Journal of Histochemistry and Cytochemistry 47 1999 757 768
26. J. Psotová, M. Kolár, J. Sousek, Z. Svagera, J. Vicar, and J. Ulrichová Biological activities of Prunella vulgaris extract Phytotherapy Research 17 2003 1082 1087
27. R. Rasool, B.A. Ganai, S. Akbar, A.N. Kamili, and A. Masood Phytochemical screening of Prunella vulgaris L. - an important medicinal plant of Kashmir Pakistan Journal of Pharmaceutical Sciences 23 2010 399 402
28. V. Swarup, J. Ghosh, S. Ghosh, A. Saxena, and A. Basu Antiviral and anti-inflammatory effects of rosmarinic acid in an experimental murine model of Japanese encephalitis Antimicrobial Agents and Chemotherapy 51 2007 3367 3370
29. T. Song, K. Barua, G. Buseman, and P.A. Murphy Soy isoflavone analysis: quality control and new internal standard The American Journal of Clinical Nutrition 68 1998 1474 1479
30. R.A. Walgren, U.K. Walle, and T. Walle Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells Biochemical Pharmacology 55 1998 1721 1727
31. H.S. Young, H.Y. Chung, C.K. Lee, K.Y. Park, T. Yokozawa, and H. Oura Ursolic acid inhibits aflatoxin B1-induced mutagenicity in a Salmonella assay system Biological and Pharmaceutical Bulletin 17 1994 990 992
32. A. Zdarilová, A. Svobodová, V. Simánek, and J. Ulrichová Prunella vulgaris extract and rosmarinic acid suppress lipopolysaccharide-induced alteration in human gingival fibroblasts Toxicology In Vitro 23 2009 386 392