Exploring food effects on indinavir absorption with human intestinal fluids in the mouse intestine

European Journal of Pharmaceutical Sciences

Volumn 49, Issue 1, 2013, Pages 27-32

  Holmstock, Nico ^a   Bruyn, Tom De ^a   Bevernage, Jan ^a   Annaert, Pieter ^a   Mols, Raf ^a   Tack, Jan ^b   Augustijns, Patrick ^a  

^a DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Food effects; Human intestinal fluids; in situ intestinal perfusion; Indinavir; Mouse

Indexed keywords

BILE SALT; INDINAVIR; PHOSPHATIDYLCHOLINE; RITONAVIR; TAUROURSODEOXYCHOLIC ACID; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITOR;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG ABSORPTION; DRUG PENETRATION; DRUG SOLUBILITY; FOOD DRUG INTERACTION; INTESTINE ABSORPTION; INTESTINE FLUID; INTESTINE PERFUSION; MALE; MOUSE; NONHUMAN; OSMOLALITY; PRIORITY JOURNAL; THERMODYNAMICS; VISCOSITY; ANIMAL; BODY FLUID; CACO 2 CELL LINE; CHEMISTRY; DRUG EFFECTS; FOOD; HUMAN; INTESTINE; METABOLISM; SOLUBILITY;

ANIMALS; BODY FLUIDS; CACO-2 CELLS; FOOD; FOOD-DRUG INTERACTIONS; HIV PROTEASE INHIBITORS; HUMANS; INDINAVIR; INTESTINAL ABSORPTION; INTESTINES; MALE; MICE; SOLUBILITY;

EID: 84874936574     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2013.01.012     Document Type: Article

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