Intestinal perfusion with mesenteric blood sampling in wild-type and knockout mice: Evaluation of a novel tool in biopharmaceutical drug profiling

Drug Metabolism and Disposition

Volumn 37, Issue 6, 2009, Pages 1334-1337

  Mols, Raf ^a   Brouwers, Joachim ^a   Schinkel, Alfred H ^b   Annaert, Pieter ^a   Augustijns, Patrick ^a  

^a DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ATENOLOL; GLYCOPROTEIN P; METOPROLOL; TALINOLOL; VERAPAMIL;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; INTESTINE ABSORPTION; INTESTINE MUCOSA PERMEABILITY; INTESTINE PERFUSION; KNOCKOUT MOUSE; MALE; MESENTERIC VEIN; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE; WILD TYPE;

ANIMALS; ANTIHYPERTENSIVE AGENTS; ATENOLOL; CACO-2 CELLS; HUMANS; INTESTINES; MALE; MESENTERY; METOPROLOL; MICE; MICE, KNOCKOUT; P-GLYCOPROTEIN; PERFUSION; PROPANOLAMINES;

MUS; RATTUS;

EID: 66649103351     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.109.026591     Document Type: Article

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