Mitochondria-mediated cardioprotection by trimetazidine in rabbit heart failure

Journal of Molecular and Cellular Cardiology

Volumn 59, Issue , 2013, Pages 41-54

  Dedkova, Elena N ^a   Seidlmayer, Lea K ^a   Blatter, Lothar A ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Heart failure; Mitochondrial complex II mediated ROS generation; Mitochondrial nitric oxide synthase; Permeability transition pore; adrenergic signaling; Trimetazidine

Indexed keywords

4 BROMOTIGLIC ACID; ACYLTRANSFERASE INHIBITOR; CALCIUM; ISOPRENALINE; MITOCHONDRIAL NITRIC OXIDE SYNTHASE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; NITRIC OXIDE SYNTHASE; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); TRIMETAZIDINE; UNCLASSIFIED DRUG; ACETYL COENZYME A ACYLTRANSFERASE; CARRIER PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM SIGNALING; CARDIAC MUSCLE CELL; CYTOSOL; DRUG MECHANISM; ELECTROSTIMULATION; FATTY ACID OXIDATION; HEART FAILURE; HEART MITOCHONDRION; HEART PROTECTION; HEART VENTRICLE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; RABBIT MODEL; RESPIRATORY CHAIN; ANIMAL; DRUG EFFECT; ELECTRON TRANSPORT; METABOLISM; RABBIT;

ACETYL-COA C-ACYLTRANSFERASE; ANIMALS; CALCIUM; ELECTRON TRANSPORT; HEART FAILURE; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; NITRIC OXIDE SYNTHASE; RABBITS; REACTIVE OXYGEN SPECIES; TRIMETAZIDINE;

EID: 84874935310     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.01.016     Document Type: Article

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