Retinoic acid suppresses the adhesion and migration of human retinal pigment epithelial cells

Experimental Eye Research

Volumn 109, Issue , 2013, Pages 22-30

  Du, Ying Hua ^a   Hirooka, Kazuyuki ^b   Miyamoto, Osamu ^c   Bao, Yong Qin ^a   Zhang, Bin ^a   An, Jian Bin ^a   Ma, Jing Xue ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b KAGAWA UNIVERSITY   (Japan)

^c KAWASAKI MEDICAL SCHOOL   (Japan)

Author keywords

ECM; Migration; PVR; Retina; RPE

Indexed keywords

FIBRONECTIN; FIBRONECTIN 1; GELATINASE A; GELATINASE B; INTEGRIN; INTERSTITIAL COLLAGENASE; LAMININ; MESSENGER RNA; RETINOIC ACID; STROMELYSIN; TENASCIN; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UVOMORULIN;

ARTICLE; CELL ADHESION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA DETACHMENT; UPREGULATION; VITREORETINOPATHY; WOUND HEALING;

ADULT; ANIMALS; ANTINEOPLASTIC AGENTS; CELL ADHESION; CELL ADHESION MOLECULES; CELL MOVEMENT; CELLS, CULTURED; CYTOSKELETON; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RABBITS; RETINAL PIGMENT EPITHELIUM; RNA, MESSENGER; TRETINOIN; VITREORETINOPATHY, PROLIFERATIVE; WOUND HEALING;

EID: 84874749885     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2013.01.006     Document Type: Article

References (48)

1. Albini A., Iwamoto Y., Kleinman H.K., Martin G.R., Aaronson S.A., Kozlowski J.M., McEwan R.N. A rapid in vitro assay for quantitating the invasive potential of tumour cells. Cancer Res. 1987, 47:3239-3245.
2. Axel D.I., Frigge A., Dittmann J., Runge H., Spyridopoulos I., Riessen R., Viebahn R., Karsch K.R. All-trans retinoic acid regulates proliferation, migration, differentiation, and extracellular matrix turnover of human arterial smooth muscle cells. Cardiovasc. Res. 2001, 49:851-862.
3. Behzadian M.A., Wang X.L., Windsor L.J., Ghaly N., Caldwell R.B. TGF-b increases retinal endothelial cell permeability by increasing MMP-9: possible role of glial cells in endothelial barrier function. Invest. Ophthalmol. Vis. Sci. 2001, 42:853-859.
4. Blake S.M., Strasser V., Andrade N., Duit S., Hofbauer R., Schneider W.J., Nimpf J. Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration. EMBO J. 2008, 27(22):3069-3080.
5. Casari G., De Fusco M., Ciarmatori S., Zeviani M., Mora M., Fernandez P., De Michele G., Filla A., Cocozza S., Marconi R., Durr A., Fontaine B., Ballabio A. Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease. Cell. 1998, 93(6):973-983.
6. Chang Y.C., Kao Y.H., Hu D.N., Tsai L.Y., Wu W.C. All-trans retinoic acid remodels ECM and suppresses laminin-enhanced contractility of cultured human retinal pigment epithelial cells. Exp. Eye Res. 2009, 88:900-909.
7. Chung C.Y., Zardi L., Erickson H.P. Binding of tenascin-C to soluble fibronectin and matrix fibril. J. Biol. Chem. 1995, 270(48):29012-29017.
8. Das A., McLamore A., Song W., McGuire P. Retinal neovascularization is suppressed with a MMP inhibitor. Arch. Ophthalmol. 1999, 117:498-503.
9. De La Paz M.A., Itoh Y., Toth C.A., Nagase H. Matrix metalloproteinases and their inhibitors in human vitreous. Invest. Ophthalmol. Vis. Sci. 1998, 39(7):1256-1260.
10. Denko N., Schindler C., Koong A., Laderoute K., Green C., Giaccia A. Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment. Clin. Cancer Res. 2000, 6:480-487.
11. Dong X., Chen N., Xie L., Wang S. Prevention of experimental proliferative vitreoretinopathy with a biodegradable intravitreal drug delivery system of all-trans retinoic acid. Retina 2006, 26(2):210-213.
12. Doyle J.W., Dowgiert R.K., Buzney S.M. Factors modulating the effect of retinoids on cultured retinal pigment epithelial cell proliferation. Curr. Eye Res. 1992, 11:753-765.
13. Fillmore H.L., VanMeter T.E., Broaddus W.C. Membrane-type matrix metalloproteinases (MT-MMPs): expression and function during glioma invasion. J. Neurooncol. 2001, 53:187-202.
14. Giebel S.J., Menicucci G., McGuire P.G., Das A. Matrix metalloproteinases in early diabetic retinopathy and their role in alteration of the blood-retinal barrier. Lab. Invest. 2005, 85:597-607.
15. Hiscott P., Waller H.A., Grierson I., Butler M.G., Scott D. Local production of fibronectin by ectopic human retinal cells. Cell. Tissue Res. 1992, 267:185-192.
16. Hu D.N., McCormick S.A., Ritch R., Pelton-Henrion K. Studies of human uveal melanocytes in vitro: isolation, purification and cultivation of human uveal melanocytes. Invest. Ophthalmol. Vis. Sci. 1993, 34:2210-2219.
17. Hynes R. Integrins: bidirectional, allosteric signaling machines. Cell. 2002, 110(6):673-687.
18. Iyer V.R., Eisen M.B., Ross D.T., Schuler G., Moore T., Lee J.C.F., Trent J.M., Staudt L.M., Hudson J., Boguski M.S., Lashkari D., Shalon D., Botstein D., Brown P.O. The transcriptional program in the response of human fibroblasts to serum. Science (Wash. DC) 1999, 283:83-87.
19. Jin M., He S., Wörpel V., Ryan S.J., Hinton D.R. Promotion of adhesion and migration of RPE cells to provisional extracellular matrices by TNF-alpha. Invest. Ophthalmol. Vis. Sci. 2000, 41(13):4324-4332.
20. Jung S.Y., Kim J.M., Min S.K., Kim O.B., Jang da H., Kang H.K., Min B.M. The potential of laminin-2-biomimetic short peptide to promote cell adhesion, spreading and migration by inducing membrane recruitment and phosphorylation of PKCδ. Biomaterials 2012, 33(15):3967-3979.
21. Kanamori Y., Matsushima M., Minaguchi T., Kobayashi K., Sagae S., Kudo R., Terakawa N., Nakamura Y. Correlation between expression of the matrix metalloproteinase-1 gene in ovarian cancers and an insertion/deletion polymorphism in its promoter region. Cancer Res. 1999, 59:4225-4227.
22. Kishi H., Mishima H., Yamashita U. Effects of retinoic acid and TGF-beta 1 on the proliferation and melanin synthesis in chick retinal pigment epithelial cells in vitro. Curr. Eye Res. 1998, 7:483-486.
23. Luo D., Mari B., Stoll I., Anglard P. Alternative splicing and promoter usage generates an intracellular stromelysin 3 isoform directly translated as an active matrix metalloproteinase. J. Biol. Chem. 2002, 277(28):25527-25536.
24. Margadant C., Monsuur H.N., Norman J.C., Sonnenberg A. Mechanisms of integrin activation and trafficking. Curr. Opin. Cell. Biol. 2011, 23(5):607-614.
25. Menon L.G., Kuttan R., Kuttan G. Anti-metastatic activity of curcumin and catechin. Cancer Lett. 1999, 14:159-165.
26. Morini M., Mottolese M., Ferrari N., Ghiorzo F., Buglioni S., Mortarini R., Noonan D.M., Natali P.G., Albini A. The a 3 b 1 integrin is associated with mammary carcinoma cell metastasis, invasion, and gelatinase B (MMP-9) activity. Int. J. Cancer 2000, 87:336-342.
27. Morino I., Hiscott P.S., McKechnie N., Grierson I. Variation in epiretinal membrane components with clinical duration of the proliferative tissue. Br. J. Ophthalmol. 1990, 74:393-399.
28. Powell W.C., Knox J.D., Navre M., Grogan T.M., Kittelson J., Nagle R.B., Bowden G.T. Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice. Cancer Res. 1993, 53(2):417-422. 15.
29. Ross D.T., Scherf U., Eisen M.B., Perou C.M., Rees C., Spellman P., Iyer V., Jeffrey S.S., Van de Rijn M., Waltham M., Pergamenschikov A., Lee J.C.F., Lashkari D., Shalon D., Myers T.G., Weinstein J.N., Botstein D., Brown P.O. Systematic variation in gene expression patterns in human cancer cell lines. Nat. Genet. 2000, 24:227-235.
30. Salzmann J., Limb G.A., Khaw P.T., Gregor Z.J., Webster L., Chignell A.H., Charteris D.G. Matrix metalloproteinases and their natural inhibitors in fibrovascular membranes of proliferative diabetic retinopathy. Br. J. Ophthalmol. 2000, 84(10):1087-1088.
31. Scott K.A., Wood E.J., Karran E.H. A matrix which prevents fibroblast-2 mediated collagen lattice contraction. FEBS Lett. 1998, 441:137-140.
32. Sheridan C.M., Occleston N.L., Hiscott P., Kon C.H., Khaw P.T., Grierson I. Matrix metalloproteinases: a role in the contraction of vitreo-retinal scar tissue. Am. J. Pathol. 2001, 159(4):1555-1566.
33. Simantov R., Silverstein R.L. CD36: a critical anti-angiogenic receptor. Front. Biosci. 2003, 1(8):s874-882.
34. Solovjov D., Pluskota E., Plow E. Distinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2. J. Biol. Chem. 2005, 280(2):1336-1345.
35. Sreenath T., Matrisian L.M., Stetler-Stevenson W., Gattoni-Celli S., Pozzatti R.O. Expression of matrix metalloproteinase genes in transformed rate cell lines of high and low metastatic potential. Cancer Res. 1992, 52:4942-4947.
36. Tamura K., Chen Y.E., Chen Q., Nyui N., Horiuchi M., Takasaki I., Tamura N., Pratt R.E., Dzau V.J., Umemura S. Expression of rennin-angiotensin system and extracellular matrix genes in cardiovascular cells and its regulation through AT1 receptor. Mol. Cell. Biochem. 2000, 212(1-2):203-209.
37. Taylor M.A., Lee Y.H., Schiemann W.P. Role of TGF-β and the tumor microenvironment during mammary tumorigenesis. Gene Expr. 2011, 15(3):117-132.
38. Uleminckx K., Vackat L., Mareel M., Fiers W., Van Roy F.V. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 1991, 66:107-119.
39. Urbano J.M., Domínguez-Giménez P., Estrada B., Martín-Bermudo M.D. PS integrins and laminins: key regulators of cell migration during Drosophila embryogenesis. PLoS One 2011, 6(9):e23893.
40. Valster A., Tran N.L., Nakada M., Berens M.E., Chan A.Y., Symons M. Cell migration and invasion assays. Methods (San Diego, Calif.) 2005, 37(2):208-215.
41. Wolf K., Friedl P. Extracellular matrix determinants of proteolytic and non-proteolytic cell migration. Trends Cell. Biol. 2011, 21(12):736-744.
42. Wong A.S., Gumbiner B.M. Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin. J. Cell. Biol. 2003, 161(6):1191-1203.
43. Wu W.C., Hu D.N., Mehta S., Chang Y.C. Effects of retinoic acid on retinal pigment epithelium from excised membranes from proliferative vitreoretinopathy. J. Ocul. Pharmacol. Ther. 2005, 21:44-54.
44. Wu W.C., Hu D.N., Roberts J.E. Phototoxicity of indocyanine green on human retinal pigment epithelium in vitro and its reduction by lutein. Photochem. Photobiol. 2005, 81:537-540.
45. Xu H., Quan H.H., Dan H., Lei T., Chang M.G., Hong J.D., Peng Z., Yu S.W., Yan N.H. Mechanical force enhances MMP-2 activation via p38 signaling pathway in human retinal pigment epithelial cells. Graefes Arch. Clin. Exp. Ophthalmol. 2009, 247:1477-1486.
46. Ye S., Eriksson P., Hamsten A., Kurkinen M., Humphries S.E., Henney A.M. Progression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expression. J. Biol. Chem. 1996, 271(22):13055-13060.
47. Yuan Y., Chen H., Ma G., Cao X., Liu Z. Reelin is involved in transforming growth factor-β1-induced cell migration in esophageal carcinoma cells. PLoS One 2012, 7(2):e31802.
48. Zhang L., Li X.X., Zhao M., He P., Yu W., Dong J., Liu G., Li C., Shi X. Antisense oligonucleotide targeting c-fos mRNA limits retinal pigment epithelial cell proliferation; a key step in the progression of proliferative vitreoretinopathy. Exp. Eye Res. 2006, 83:1405-1411.