Mechanical force enhances MMP-2 activation via p38 signaling pathway in human retinal pigment epithelial cells

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 247, Issue 11, 2009, Pages 1477-1486

  Hou, Xu ^a   Han, Quan Hong ^b   Hu, Dan ^a   Tian, Lei ^a   Guo, Chang Mei ^a   Du, Hong Jun ^a   Zhang, Peng ^a   Wang, Yu Sheng ^a   Hui, Yan Nian ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b TIANJIN EYE HOSPITAL   (China)

Author keywords

Matrix metalloproteinase; Mechanical force; Mitogen activated protein kinase; Retinal pigment epithelial cell

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; FIBRONECTIN; GELATINASE A; GELATINASE B; MAGNETITE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ADULT; ARTICLE; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME IMMUNOASSAY; ENZYME RELEASE; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; MAGNETIC FIELD; MECHANICAL STRESS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ZYMOGRAPHY;

ADULT; BLOTTING, WESTERN; CELL LINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; MAP KINASE KINASE 4; MATRIX METALLOPROTEINASE 2; MICROSCOPY, ELECTRON, SCANNING; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; STRESS, MECHANICAL;

EID: 70349864993     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-009-1135-1     Document Type: Article

References (48)

1. Hollyfield JG, Varner HH, Rayborn ME, Osterfeld AM (1989) Retinal attachment to the pigment epithelium: Linkage through an extracellular sheath surrounding cone photoreceptors. Retina. 9:59-68
2. Kalnins VI, Sandig M, Hergott GJ, Nagai H (1995) Microfilament organization and wound repair in retinal pigment epithelium. Biochem Cell Biol. 73:709-722
3. Seko Y, Seko Y, Fujikura H, Pang J, Tokoro T, Shimokawa H (1999) Induction of vascular endothelial growth factor after application of mechanical stress to retinal pigment epithelium of the rat in vitro. Invest Ophthalmol Vis Sci. 40(13):3287-3291
4. Plantner JJ, Smine A, Quinn TA (1998) Matrix metalloproteinases and metalloproteinase inhibitors in human interphotoreceptor matrix and vitreous. Curr Eye Res. 17(2):132-140
5. De La Paz MA, Itoh Y, Toth CA, Nagase H (1998) Matrix metalloproteinases and their inhibitors in human vitreous. Invest Ophthalmol Vis Sci. 39(7):1256-1260
6. Plantner JJ, Jiang C, Smine A (1998) Increase in interphotoreceptor matrix gelatinase A (MMP-2) associated with age-related macular degeneration. Exp Eye Res. 67:637-645
7. Steen B, Sejersen S, Berglin L, Seregard S, Kvanta A (1998) Matrix metalloproteinases and metalloproteinase inhibitors in choroidal neovascular membranes. Invest Ophthalmol Vis Sci. 39:2194-2200
8. Sheridan CM, Occleston NL, Hiscott P, Kon CH, Khaw PT, Grierson I (2001) Matrix metalloproteinases: A role in the contraction of vitreo-retinal scar tissue. Am J Pathol. 159(4):1555-1566
9. Murphy G, Gavrilovich J (1999) Proteolysis and cell migration: Creating a path? Curr Opin Cell Biol. 1:614-621
10. Alexander JP, Bradley JM, Gabourel JD, Acott TS (1990) Expression of matrix metalloproteinases and inhibitor by human retinal pigment epithelium. Invest Ophthalmol Vis Sci. 31(12):2520-2528
11. Weinreb RN, Kashiwagi K, Kashiwagi F, Tsukahara S, Lindsey JD (1997) Prostaglandins increase matrix metalloproteinase release from human ciliary smooth muscle cells. Invest Ophthalmol Vis Sci. 38(13):2772-2780
12. Hunt RC, Fox A, al Pakalnis V, Sigel MM, Kosnosky W, Choudhury P, Black EP (1993) Cytokines cause cultured retinal pigment epithelial cells to secrete metalloproteinases and to contract collagen gels. Invest Ophthalmol Vis Sci. 34(11):3179-3186
13. Salzmann J, Limb GA, Khaw PT, Gregor ZJ, Webster L, Chignell AH, Charteris DG (2000) Matrix metalloproteinases and their natural inhibitors in fibrovascular membranes of proliferative diabetic retinopathy. Br J Ophthalmol. 84(10):1087-1088
14. Goto T, Mikami KI, Miura K, Ohshima S, Yoneyama K, Nakane K, Watanabe D, Otaka M, Watanabe S (2004) Mechanical stretch induces matrix metalloproteinase 1 production in human hepatic stellate cells. Pathophysiology. 11(3):153-158
15. Wang TL, Yang YH, Chang H, Hung CR (2004) Angiotensin II signals mechanical stretch-induced cardiac matrix metalloproteinase expression via JAK-STAT pathway. J Mol Cell Cardiol. 37(3):785-794
16. Brown MD, Hudlicka O (2003) Modulation of physiological angiogenesis in skeletal muscle by mechanical forces: Involvement of VEGF and metalloproteinases. Angiogenesis. 6(1):1-14
17. Wang BW, Chang H, Lin S, Kuan P, Shyu KG (2003) Induction of matrix metalloproteinases-14 and -2 by cyclical mechanical stretch is mediated by tumor necrosis factor-alpha in cultured human umbilical vein endothelial cells. Cardiovasc Res. 59(2):460-469
18. Grote K, Flach I, Luchtefeld M, Akin E, Holland SM, Drexler H, Schieffer B (2003) Mechanical stretch enhances mRNA expression and proenzyme release of matrix metalloproteinase-2 (MMP-2) via NAD(P)H oxidase-derived reactive oxygen species. Circ Res. 13;92(11):e80-86
19. Han QH, Hui YN, Du HJ, Zhang WJ, Ma JX, Wang SY (2001) Migration of retinal pigment epithelial cells in vitro modulated by monocyte chemotactic protein-1: Enhancement and inhibition. Graefes Arch Clin Exp Ophthalmol. 239(7):531-538
20. Glogauer M, Ferrier J (1998) A new method for application of force to cells via ferric oxide beads. Pflugers Arch. 435(2):320-327
21. D'Addario M, Ahmad A, Xu JW, Menezes J (1999) Epstein-Barr virus envelope glycoprotein gp350 induces NF-kappaB activation and IL-1beta synthesis in human monocytes-macrophages involving PKC and PI3-K. FASEB J. 13(15):2203-2213
22. Zhang X, Sakamoto T, Hata Y, Kubota T, Hisatomi T, Murata T, Ishibashi T, Inomata H (2002) Expression of matrix metalloproteinases and their inhibitors in experimental retinal ischemia-reperfusion injury in rats. Exp Eye Res. 74(5):577-584
23. Zhang XG, Hui YN, Han QH, Hou X, Huang XF, Ma JX (2006) Cytoskeleton changes of cultured human retinal pigment epithelial cells in a mechanical stress model. Zhonghua Yan Ke Za Zhi. 42(2):121-126
24. Zhang XG, Hui YN, Han QH, Hou X, Chen LJ, Ma JX (2005) Effects of mechanical stress on expressions of monocyte chemoattractant protein-1 and interleukin-8 of cultured human retinal pigment epithelial cells. Zhonghua Yi Xue Za Zhi. 85(32):2264-2268
25. Webster L, Chignell AH, Limb GA (1999) Predominance of MMP-1 and MMP-2 in epiretinal and subretinal membranes of proliferative vitreoretinopathy. Exp Eye Res. 68:91-98
26. Hiscott P, Sheridan C, Magee RM, Grierson I (1999) Matrix and the retinal pigment epithelium in proliferative retinal disease. Prog Retinal Eye Res. 18:167-190
27. Brown D, Hamdi H, Bahri S, Kenney MC (1994) Characterization of an endogenous metalloproteinase in human vitreous. Curr Eye Res. 13(9):639-647
28. Brown DJ, Bishop P, Hamdi H, Kenney MC (1996) Cleavage of structural components of mammalian vitreous by endogenous matrix metalloproteinase-2. Curr Eye Res. 15(4):439-445
29. Kon CH, Occleston NL, Charteris D, Daniels J, Aylward GW, Khaw PT (1998) A prospective study of matrix metalloproteinases in proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci. 39(8):1524-1529
30. Immonen I, Konttinen YT, Sorsa T, Tommila P, Siren V (1996) Proteinases in subretinal fluid. Graefes Arch Clin Exp Ophthalmol. 234(2):105-109
31. Noda K, Ishida S, Inoue M, Obata K, Oguchi Y, Okada Y, Ikeda E (2003) Production and activation of matrix metalloproteinase-2 in proliferative diabetic retinopathy. Invest Ophthalmol Vis Sci. 44(5):2163-2170
32. Amin S, Chong NH, Bailey TA, Zhang J, Knupp C, Cheetham ME, Greenwood J, Luthert PJ (2004) Modulation of Sub-RPE deposits in vitro: A potential model for age-related macular degeneration. Invest Ophthalmol Vis Sci. 45(5):1281-1288
33. Cousins SW, Marin-Castano ME, Espinosa-Heidmann DG, Alexandridou A, Striker L, Elliot S (2003) Female gender, estrogen loss, and Sub-RPE deposit formation in aged mice. Invest Ophthalmol Vis Sci. 44(3):1221-1229
34. Marin-Castano ME, Elliot SJ, Potier M, Karl M, Striker LJ, Striker GE, Csaky KG, Cousins SW (2003) Regulation of estrogen receptors and MMP-2 expression by estrogens in human retinal pigment epithelium. Invest Ophthalmol Vis Sci. 44(1):50-59
35. Padgett LC, Lui GM, Werb Z, LaVail MM (1997) Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in the retinal pigment epithelium and interphotoreceptor matrix: Vectorial secretion and regulation. Exp Eye Res. 64(6):927-938
36. Eichler W, Friedrichs U, Thies A, Tratz C, Wiedemann P (2002) Modulation of matrix metalloproteinase and TIMP-1 expression by cytokines in human RPE cells. Invest Ophthalmol Vis Sci. 43(8):2767-2773
37. Tamura K, Chen YE, Chen Q, Nyui N, Horiuchi M, Takasaki I, Tamura N, Pratt RE, Dzau VJ, Umemura S (2000) Expression of renin-angiotensin system and extracellular matrix genes in cardiovascular cells and its regulation through AT1 receptor. Mol Cell Biochem. 212(1-2):203-209
38. Ishida T, Haneda M, Maeda S, Koya D, Kikkawa R (1999) Stretch-induced overproduction of fibronectin in mesangial cells is mediated by the activation of mitogen-activated protein kinase. Diabetes. 48(3):595-602
39. Silver FH, Siperko LM (2003) Mechanosensing and mechanochemical transduction: How is mechanical energy sensed and converted into chemical energy in an extracellular matrix? Crit Rev Biomed Eng. 31(4):255-331
40. Ruwhof C, van der Laarse A (2000) Mechanical stress-induced cardiac hypertrophy: Mechanisms and signal transduction pathways. Cardiovasc Res. 47(1):23-37
41. Raingeaud J, Gupta S, Rogers J, Dickens M, Han J, Ulevitch RJ, Davis RJ (1995) Pro-inflammatory cytokines and environmental stress cause p38 MAP kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 270:7420-7426
42. Han J, Lee JD, Bibbs L, Ulevitch RJ (1994) A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265:808-811
43. Liang F, Gardner DG (1999) Mechanical strain activates BNP gene transcription through a p38/NF-kappaB-dependent mechanism. J Clin Invest. 104(11):1603-1612
44. Wang J, Seth A, McCulloch CA (2000) Force regulates smooth muscle actin in cardiac fibroblasts. Am J Physiol Heart Circ Physiol. 279(6):H2776-H2785
45. D'Addario M, Arora PD, Ellen RP, McCulloch CA (2002) Interaction of p38 and Sp1 in a mechanical force-induced, beta 1 integrin-mediated transcriptional circuit that regulates the actin-binding protein filamin-A. J Biol Chem. 277(49):47541-47550
46. von Offenberg Sweeney N, Cummins PM, Birney YA, Cullen JP, Redmond EM, Cahill PA (2004) Cyclic strain-mediated regulation of endothelial matrix metalloproteinase-2 expression and activity. Cardiovasc Res. 63(4):625-634
47. Wang J, Seth A, McCulloch CA (2000) Force regulates smooth muscle actin in cardiac fibroblasts. Am J Physiol Heart Circ Physiol. 279(6):H2776-H2785
48. Gruden G, Zonca S, Hayward A, Thomas S, Maestrini S, Gnudi L, Viberti GC (2000) Mechanical stretch-induced fibronectin and transforming growth factor-beta1 production in human mesangial cells is p38 mitogen-activated protein kinase-dependent. Diabetes. 49(4):655-661