TGF-β increases retinal endothelial cell permeability by increasing MMP-9: Possible role of glial cells in endothelial barrier function

Investigative Ophthalmology and Visual Science

Volumn 42, Issue 3, 2001, Pages 853-859

  Behzadian, M A ^a   Wang, X L ^a   Windsor, L J ^a   Ghaly, N ^a   Caldwell, R B ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE B; OCCLUDIN; TRANSFORMING GROWTH FACTOR BETA;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; BLOOD RETINA BARRIER; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME SYNTHESIS; GLIA CELL; HYPOXIA; IMMUNOCYTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA DISEASE; WESTERN BLOTTING; ZYMOGRAPHY;

ANIMALS; BLOOD-RETINAL BARRIER; BLOTTING, WESTERN; CATTLE; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; COCULTURE TECHNIQUES; ENDOTHELIUM, VASCULAR; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; MATRIX METALLOPROTEINASE 9; MEMBRANE PROTEINS; NEUROGLIA; RATS; RETINAL VESSELS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0035097495     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Metastatic potential correlates with enzymatic degradation of basement membrane collagen
2. Genes for extracellular-matrix-degrading metalloproteinases and their inhibitor, TIMP, are expressed during early mammalian development
3. Metalloproteinases and their inhibitors in matrix remodeling
4. Disruption of cadherin-related junctions triggers autocrine expression of vascular endothelial growth factor in bovine aortic endothelial cells. Effects on cell proliferation and death resistance
5. Activation of the 92-kDa gelatinase by stromelysin and 4-aminophenylmercuric acetate
6. Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion
7. Complete structure of the human gene for 92-kDa type IV collagenase. Divergent regulation of expression for the 97- and 72-kilodalton enzyme genes in HT-1080 cells
8. Gelatinase B in proliferative vitreoretinal disorders
9. Characterization of an endogenous metalloproteinase in human vitreous
10. Matrix metallo-proteinase expression in human retinal microvascular cells
11. Matrix metalloproteinases and metalloproteinase inhibitors in choroidal neovascular membranes
12. Increase in interphotoreceptor matrix gelatinase A (MMP-2) associated with age-related macular degeneration
13. Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation
14. Inhibition of angiogenesis by tissue inhibitor of metalloproteinase
15. In vitro angiogenesis on the human amniotic membrane: Requirement for basic fibroblast growth factor-induced proteinases
16. Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells
17. Vascular endothelial growth factor increases release of gelatinase A and decreases release of tissue inhibitor of metalloproteinases by microvascular endothelial cells in vitro
18. Astrocytes modulate retinal vasculogenesis, effects on fibronectin expression
19. Astrocytes modulate retinal vasculogenesis: Effects on endothelial cell differentiation
20. Astrocytes induce neural microvascular endothelial cells to form capillary-like structures in vitro
21. Astroglial-induced in vitro angiogenesis: Requirements for RNA and protein synthesis
22. Angiostatic role of astrocytes: Suppression of vascular endothelial cell growth by TGF-β and other inhibitory factors
23. Effects of hypoxia on glial cell expression of angiogenesis regulating factors VEGF and TGF-β
24. Inhibition of endothelial cell movement by pericytes and smooth muscle cells: Activation of a latent transforming growth factor-β 1-like molecule by plasmin during co-culture
25. An activated form of transforming growth factor beta is produced by co-culture of endothelial cells and pericytes
26. VEGF-induced permeability increase is mediated by caveolae
27. Cultured Müller cells have high levels of epidermal growth factor receptors
28. Prostaglandins increase matrix metalloproteinase release from human ciliary smooth muscle cells
29. Multiple modes of activation of latent human fibroblast collagenase: Evidence for the role of a Cys73 active-site zinc complex in latency and a cysteine switch mechanism for activation
30. Tissue inhibitor of metalloproteinase (TIMP-2) a new member of the metalloproteinase inhibitor family
31. Mosaic structure of the secreted ECM metalloproteases and interaction of the type IV collagenases with inhibitors
32. Localization of matrix metalloproteinase 3 (stromelysin) in osteoarthritic cartilage and synovium
33. A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases
34. Continuously recording fluorescent assay optimized for five human matrix metalloproteinases
35. r 72.000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines
36. Quantitative zymography: Detection of picogram quantities of gelatinases
37. Purification and characterization of matrix metalloproteinase 9 from U937 monocytic leukaemia and HT1080 fibrosarcoma cells
38. 92K-LG(MMP-9) and 72K-LG(MMP-2) are produced in vivo by human oral squamous cell carci-nomas and can enhance FIB-CL (MMP-1) activity in vitro
39. Catabolism and turnover of collagens: Collagenase 1
40. Monoclonal antibody that immunoreacts with a subclass of human receptors for epidermal growth factor
41. Vascular endothelial growth factor induces rapid phosphorylation of tight junction proteins occludin and zonula occluden1
42. A major advance in the use of growth factors to enhance wound healing
43. Examining the relationship between the gelatinolytic balance and the invasive capacity of endothelial cells
44. SV40-transformed human lung fibroblasts secrete a 92-kDa type-iv collagenase which is identical to that secreted by normal human macrophages
45. Biphasic effect of transforming growth factor-β1 on in vitro angiogenesis
46. Mechanisms of retinal and choroidal neovascularization
47. Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells
48. Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cells
49. Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo
50. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
51. Expression of metalloproteinases and metalloproteinase inhibitors by fetal astrocytes and glioma cells
52. Expressions of matrilysin and stromelysin in human glioma cells
53. r 92.000 gelatinase secreted by normal and malignant human cells: Isolation and characterization of the enzyme from HT1080 tumor cells
54. Activation and novel processing of matrix metalloproteinases by a thiol-proteinase from the oral anaerobe prophyromonas gingivalis
55. Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion