Hierarchical accumulation of RyR post-translational modifications drives disease progression in dystrophic cardiomyopathy

Cardiovascular Research

Volumn 97, Issue 4, 2013, Pages 666-675

  Kyrychenko, Sergii ^a   Poláková, Eva ^a,c   Kang, Chifei ^a   Pocsai, Krisztina ^a   Ullrich, Nina D ^b   Niggli, Ernst ^b   Shirokova, Natalia ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF BERN   (Switzerland)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Ca2+ signals; Dystrophic cardiomyopathy; Excitation contraction coupling; Ryanodine receptor

Indexed keywords

ANTIOXIDANT; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II INHIBITOR; CALCIUM CHANNEL; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; OXIDOREDUCTASE INHIBITOR; PROTEIN SERINE THREONINE KINASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE INHIBITOR; RYANODINE RECEPTOR; UNCLASSIFIED DRUG;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM SIGNALING; CARDIOMYOPATHY; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DISEASE COURSE; DUCHENNE MUSCULAR DYSTROPHY; DYSTROPHIC CARDIOMYOPATHY; EXCITATION CONTRACTION COUPLING; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART PERFORMANCE; HYPERSENSITIVITY; MECHANICAL STRESS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN SECRETION; SARCOPLASMIC RETICULUM;

ANIMALS; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CARDIOMYOPATHIES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DISEASE PROGRESSION; DYSTROPHIN; MICE; MICE, INBRED C57BL; MICE, INBRED MDX; MUSCULAR DYSTROPHY, DUCHENNE; MYOCARDIUM; MYOCYTES, CARDIAC; NADPH OXIDASE; OXIDATION-REDUCTION; PROTEIN PROCESSING, POST-TRANSLATIONAL; REACTIVE OXYGEN SPECIES; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL;

EID: 84874735635     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs425     Document Type: Article

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