메뉴 건너뛰기




Volumn 19, Issue 7-8, 2013, Pages 1015-1022

Dedifferentiation and redifferentiation of articular chondrocytes from surface and middle zones: Changes in MicroRNAs-221/-222, -140, and -143/145 expression

Author keywords

[No Author keywords available]

Indexed keywords

BIOMECHANICS; BODY FLUIDS; CELL CULTURE; GENE EXPRESSION; GROWTH KINETICS; RNA; THREE DIMENSIONAL COMPUTER GRAPHICS; TISSUE; TISSUE HOMEOSTASIS;

EID: 84874688328     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2012.0055     Document Type: Article
Times cited : (42)

References (57)
  • 1
    • 0031194440 scopus 로고    scopus 로고
    • Depth-dependent confined compression modulus of fullthickness bovine articular cartilage
    • Schinagl, R.M., Gurskis, D., Chen, A.C., and Sah, R.L. Depth-dependent confined compression modulus of fullthickness bovine articular cartilage. J Orthop Res 15, 499, 1997.
    • (1997) J Orthop Res , vol.15 , pp. 499
    • Schinagl, R.M.1    Gurskis, D.2    Chen, A.C.3    Sah, R.L.4
  • 2
    • 0031279438 scopus 로고    scopus 로고
    • Finite deformation biphasic material properties of bovine articular cartilage from confined compression experiments
    • Ateshian, G.A., Warden, W.H., Kim, J.J., Grelsamer, R.P., and Mow, V.C. Finite deformation biphasic material properties of bovine articular cartilage from confined compression experiments. J Biomech 30, 1157, 1997.
    • (1997) J Biomech , vol.30 , pp. 1157
    • Ateshian, G.A.1    Warden, W.H.2    Kim, J.J.3    Grelsamer, R.P.4    Mow, V.C.5
  • 3
    • 27744606356 scopus 로고    scopus 로고
    • Polymer scaffolds fabricated with pore-size gradients as a model for studying the zonal organization within tissue-engineered cartilage constructs
    • Woodfield, T.B., Van Blitterswijk, C.A., De Wijn, J., Sims, T.J., Hollander, A.P., and Riesle, J. Polymer scaffolds fabricated with pore-size gradients as a model for studying the zonal organization within tissue-engineered cartilage constructs. Tissue Eng 11, 1297, 2005.
    • (2005) Tissue Eng , vol.11 , pp. 1297
    • Woodfield, T.B.1    Van Blitterswijk, C.A.2    De Wijn, J.3    Sims, T.J.4    Hollander, A.P.5    Riesle, J.6
  • 5
    • 70349954683 scopus 로고    scopus 로고
    • Tissue engineering of articular cartilage with biomimetic zones
    • Klein, T.J., Malda, J., Sah, R.L., and Hutmacher, D.W. Tissue engineering of articular cartilage with biomimetic zones. Tissue Eng Part B Rev 15, 143, 2009.
    • (2009) Tissue Eng Part B Rev , vol.15 , pp. 143
    • Klein, T.J.1    Malda, J.2    Sah, R.L.3    Hutmacher, D.W.4
  • 9
    • 0037258317 scopus 로고    scopus 로고
    • The use of specific chondrocyte populations to modulate the properties of tissue-engineered cartilage
    • Waldman, S.D., Grynpas, M.D., Pilliar, R.M., and Kandel, R.A. The use of specific chondrocyte populations to modulate the properties of tissue-engineered cartilage. J Orthop Res 21, 132, 2003.
    • (2003) J Orthop Res , vol.21 , pp. 132
    • Waldman, S.D.1    Grynpas, M.D.2    Pilliar, R.M.3    Kandel, R.A.4
  • 10
    • 77649266099 scopus 로고    scopus 로고
    • Localization of the potential zonal marker clusterin in native cartilage and in tissue-engineered constructs
    • Malda, J., ten Hoope, W., Schuurman, W., van Osch, G.J., van Weeren, P.R., and Dhert, W.J. Localization of the potential zonal marker clusterin in native cartilage and in tissue-engineered constructs. Tissue Eng Part A 16, 897, 2010.
    • (2010) Tissue Eng Part A , vol.16 , pp. 897
    • Malda, J.1    Ten Hoope, W.2    Schuurman, W.3    Van Osch, G.J.4    Van Weeren, P.R.5    Dhert, W.J.6
  • 12
    • 78649760574 scopus 로고    scopus 로고
    • Unique biomaterial compositions direct bone marrow stem cells into specific chondrocytic phenotypes corresponding to the various zones of articular cartilage
    • Nguyen, L.H., Kudva, A.K., Guckert, N.L., Linse, K.D., and Roy, K. Unique biomaterial compositions direct bone marrow stem cells into specific chondrocytic phenotypes corresponding to the various zones of articular cartilage. Biomaterials 32, 1327, 2011.
    • (2011) Biomaterials , vol.32 , pp. 1327
    • Nguyen, L.H.1    Kudva, A.K.2    Guckert, N.L.3    Linse, K.D.4    Roy, K.5
  • 13
    • 79960836277 scopus 로고    scopus 로고
    • Engineering articular cartilage with spatially-varying matrix composition and mechanical properties from a single stem cell population using a multi-layered hydrogel
    • Nguyen, L.H., Kudva, A.K., Saxena, N.S., and Roy, K. Engineering articular cartilage with spatially-varying matrix composition and mechanical properties from a single stem cell population using a multi-layered hydrogel. Biomaterials 32, 6946, 2011.
    • (2011) Biomaterials , vol.32 , pp. 6946
    • Nguyen, L.H.1    Kudva, A.K.2    Saxena, N.S.3    Roy, K.4
  • 14
    • 79551630799 scopus 로고    scopus 로고
    • Autologous chondrocyte implantation: An overview of technique and outcomes
    • Batty, L., Dance, S., Bajaj, S., and Cole, B.J. Autologous chondrocyte implantation: an overview of technique and outcomes. ANZ J Surg 81, 18, 2011.
    • (2011) ANZ J Surg , vol.81 , pp. 18
    • Batty, L.1    Dance, S.2    Bajaj, S.3    Cole, B.J.4
  • 15
    • 0032029962 scopus 로고    scopus 로고
    • Expression of a stable articular cartilage phenotype without evidence of hypertrophy by adult human articular chondrocytes in vitro
    • Binette, F., McQuaid, D.P., Haudenschild, D.R., Yaeger, P.C., McPherson, J.M., and Tubo, R. Expression of a stable articular cartilage phenotype without evidence of hypertrophy by adult human articular chondrocytes in vitro. J Orthop Res 16, 207, 1998.
    • (1998) J Orthop Res , vol.16 , pp. 207
    • Binette, F.1    McQuaid, D.P.2    Haudenschild, D.R.3    Yaeger, P.C.4    McPherson, J.M.5    Tubo, R.6
  • 16
    • 1642285785 scopus 로고    scopus 로고
    • Changes in the ratio of type-I and type-II collagen expression during monolayer culture of human chondrocytes
    • Marlovits, S., Hombauer, M., Truppe, M., Vecsei, V., and Schlegel, W. Changes in the ratio of type-I and type-II collagen expression during monolayer culture of human chondrocytes. J Bone Joint Surg Br 86, 286, 2004.
    • (2004) J Bone Joint Surg Br , vol.86 , pp. 286
    • Marlovits, S.1    Hombauer, M.2    Truppe, M.3    Vecsei, V.4    Schlegel, W.5
  • 17
    • 46449139072 scopus 로고    scopus 로고
    • Quantitative analysis of gene expression in human articular chondrocytes assigned for autologous implantation
    • Barlic, A., Drobnic, M., Malicev, E., and Kregar-Velikonja, N. Quantitative analysis of gene expression in human articular chondrocytes assigned for autologous implantation. J Orthop Res 26, 847, 2008.
    • (2008) J Orthop Res , vol.26 , pp. 847
    • Barlic, A.1    Drobnic, M.2    Malicev, E.3    Kregar-Velikonja, N.4
  • 19
    • 49449100628 scopus 로고    scopus 로고
    • Nuclear deformation and expression change of cartilaginous genes during in vitro expansion of chondrocytes
    • Hoshiba, T., Yamada, T., Lu, H., Kawazoe, N., Tateishi, T., and Chen, G. Nuclear deformation and expression change of cartilaginous genes during in vitro expansion of chondrocytes. Biochem Biophys Res Commun 374, 688, 2008.
    • (2008) Biochem Biophys Res Commun , vol.374 , pp. 688
    • Hoshiba, T.1    Yamada, T.2    Lu, H.3    Kawazoe, N.4    Tateishi, T.5    Chen, G.6
  • 20
    • 70349484846 scopus 로고    scopus 로고
    • Mechanical properties and gene expression of chondrocytes on micropatterned substrates following dedifferentiation in monolayer
    • Darling, E.M., Pritchett, P.E., Evans, B.A., Superfine, R., Zauscher, S., and Guilak, F. Mechanical properties and gene expression of chondrocytes on micropatterned substrates following dedifferentiation in monolayer. Cell Mol Bioeng 2, 395, 2009.
    • (2009) Cell Mol Bioeng , vol.2 , pp. 395
    • Darling, E.M.1    Pritchett, P.E.2    Evans, B.A.3    Superfine, R.4    Zauscher, S.5    Guilak, F.6
  • 21
    • 14244270059 scopus 로고    scopus 로고
    • Rapid phenotypic changes in passaged articular chondrocyte subpopulations
    • Darling, E.M., and Athanasiou, K.A. Rapid phenotypic changes in passaged articular chondrocyte subpopulations. J Orthop Res 23, 425, 2005.
    • (2005) J Orthop Res , vol.23 , pp. 425
    • Darling, E.M.1    Athanasiou, K.A.2
  • 23
    • 0020369710 scopus 로고
    • Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels
    • Benya, P.D., and Shaffer, J.D. Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels. Cell 30, 215, 1982.
    • (1982) Cell , vol.30 , pp. 215
    • Benya, P.D.1    Shaffer, J.D.2
  • 24
    • 0022880391 scopus 로고
    • Clonal analysis of the population of chondrocytes from the Swarm rat chondrosarcoma in agarose culture
    • Sun, D., Aydelotte, M.B., Maldonado, B., Kuettner, K.E., and Kimura, J.H. Clonal analysis of the population of chondrocytes from the Swarm rat chondrosarcoma in agarose culture. J Orthop Res 4, 427, 1986.
    • (1986) J Orthop Res , vol.4 , pp. 427
    • Sun, D.1    Aydelotte, M.B.2    Maldonado, B.3    Kuettner, K.E.4    Kimura, J.H.5
  • 25
    • 0028276648 scopus 로고
    • Reexpression of cartilage-specific genes by dedifferentiated human articular chondrocytes cultured in alginate beads
    • Bonaventure, J., Kadhom, N., Cohen-Solal, L., Ng, K.H., Bourguignon, J., Lasselin, C., and Freisinger, P. Reexpression of cartilage-specific genes by dedifferentiated human articular chondrocytes cultured in alginate beads. Exp Cell Res 212, 97, 1994.
    • (1994) Exp Cell Res , vol.212 , pp. 97
    • Bonaventure, J.1    Kadhom, N.2    Cohen-Solal, L.3    Ng, K.H.4    Bourguignon, J.5    Lasselin, C.6    Freisinger, P.7
  • 26
    • 0026580553 scopus 로고
    • Differential effect of transforming growth factor beta on freshly isolated and cultured articular chondrocytes
    • van der Kraan, P., Vitters, E., and van den Berg, W. Differential effect of transforming growth factor beta on freshly isolated and cultured articular chondrocytes. J Rheumatol 19, 140, 1992.
    • (1992) J Rheumatol , vol.19 , pp. 140
    • Van Der Kraan, P.1    Vitters, E.2    Van Den Berg, W.3
  • 27
    • 0029757428 scopus 로고    scopus 로고
    • Effect of growth factors on matrix synthesis by human nasal chondrocytes cultured in monolayer and in agar
    • Bujia, J., Pitzke, P., Kastenbauer, E., Wilmes, E., and Hammer, C. Effect of growth factors on matrix synthesis by human nasal chondrocytes cultured in monolayer and in agar. Eur Arch Otorhinolaryngol 253, 336, 1996.
    • (1996) Eur Arch Otorhinolaryngol , vol.253 , pp. 336
    • Bujia, J.1    Pitzke, P.2    Kastenbauer, E.3    Wilmes, E.4    Hammer, C.5
  • 28
    • 46449116986 scopus 로고    scopus 로고
    • Effects of exogenous IGF-1 delivery on the early expression of IGF-1 signaling molecules by alginate embedded chondrocytes
    • Yoon, D.M., and Fisher, J.P. Effects of exogenous IGF-1 delivery on the early expression of IGF-1 signaling molecules by alginate embedded chondrocytes. Tissue Eng Part A 14, 1263, 2008.
    • (2008) Tissue Eng Part A , vol.14 , pp. 1263
    • Yoon, D.M.1    Fisher, J.P.2
  • 31
    • 73649139221 scopus 로고    scopus 로고
    • Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes
    • Tardif, G., Hum, D., Pelletier, J.P., Duval, N., and Martel-Pelletier, J. Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes. BMC Musculoskelet Disord 10, 148, 2009.
    • (2009) BMC Musculoskelet Disord , vol.10 , pp. 148
    • Tardif, G.1    Hum, D.2    Pelletier, J.P.3    Duval, N.4    Martel-Pelletier, J.5
  • 32
    • 56649084972 scopus 로고    scopus 로고
    • Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks
    • Iliopoulos, D., Malizos, K.N., Oikonomou, P., and Tsezou, A. Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks. PLoS One 3, e3740, 2008.
    • (2008) PLoS One , vol.3
    • Iliopoulos, D.1    Malizos, K.N.2    Oikonomou, P.3    Tsezou, A.4
  • 34
    • 79960365689 scopus 로고    scopus 로고
    • Chondrocyte-specific microRNA-140 regulates endochondral bone development and targets Dnpep to modulate bone morphogenetic protein signaling
    • Nakamura, Y., Inloes, J.B., Katagiri, T., and Kobayashi, T. Chondrocyte-specific microRNA-140 regulates endochondral bone development and targets Dnpep to modulate bone morphogenetic protein signaling. Mol Cell Biol 31, 3019, 2011.
    • (2011) Mol Cell Biol , vol.31 , pp. 3019
    • Nakamura, Y.1    Inloes, J.B.2    Katagiri, T.3    Kobayashi, T.4
  • 35
    • 80051503652 scopus 로고    scopus 로고
    • Assessment of the profiling microRNA expression of differentiated and dedifferentiated human adult articular chondrocytes
    • Lin, L., Shen, Q., Zhang, C., Chen, L., and Yu, C. Assessment of the profiling microRNA expression of differentiated and dedifferentiated human adult articular chondrocytes. J Orthop Res 29, 1578, 2011.
    • (2011) J Orthop Res , vol.29 , pp. 1578
    • Lin, L.1    Shen, Q.2    Zhang, C.3    Chen, L.4    Yu, C.5
  • 36
    • 79551505437 scopus 로고    scopus 로고
    • Human primary articular chondrocytes, chondroblasts-like cells, and dedifferentiated chondrocytes: Differences in gene, micro-RNA, and protein expression and phenotype
    • Karlsen, T.A., Shahdadfar, A., and Brinchmann, J.E. Human primary articular chondrocytes, chondroblasts-like cells, and dedifferentiated chondrocytes: differences in gene, micro-RNA, and protein expression and phenotype. Tissue Eng Part C Methods 17, 219, 2011.
    • (2011) Tissue Eng Part C Methods , vol.17 , pp. 219
    • Karlsen, T.A.1    Shahdadfar, A.2    Brinchmann, J.E.3
  • 37
    • 68049096186 scopus 로고    scopus 로고
    • Profiling micro-RNA expression in bovine articular cartilage and implications for mechanotransduction
    • Dunn, W., DuRaine, G., and Reddi, A.H. Profiling micro-RNA expression in bovine articular cartilage and implications for mechanotransduction. Arthritis Rheum 60, 2333, 2009.
    • (2009) Arthritis Rheum , vol.60 , pp. 2333
    • Dunn, W.1    Duraine, G.2    Reddi, A.H.3
  • 38
    • 34547454347 scopus 로고    scopus 로고
    • Differential regulation of lubricin/ superficial zone protein by transforming growth factor beta/bone morphogenetic protein superfamily members in articular chondrocytes and synoviocytes
    • Niikura, T., and Reddi, A.H. Differential regulation of lubricin/ superficial zone protein by transforming growth factor beta/bone morphogenetic protein superfamily members in articular chondrocytes and synoviocytes. Arthritis Rheum 56, 2312, 2007.
    • (2007) Arthritis Rheum , vol.56 , pp. 2312
    • Niikura, T.1    Reddi, A.H.2
  • 39
    • 66749129094 scopus 로고    scopus 로고
    • Investigating conversion of mechanical force into biochemical signaling in three-dimensional chondrocyte cultures
    • Bougault, C., Paumier, A., Aubert-Foucher, E., and Mallein-Gerin, F. Investigating conversion of mechanical force into biochemical signaling in three-dimensional chondrocyte cultures. Nat Protoc 4, 928, 2009.
    • (2009) Nat Protoc , vol.4 , pp. 928
    • Bougault, C.1    Paumier, A.2    Aubert-Foucher, E.3    Mallein-Gerin, F.4
  • 40
    • 18744418183 scopus 로고
    • Effect of seeding density on stability of the differentiated phenotype of pig articular chondrocytes in culture
    • Watt, F.M. Effect of seeding density on stability of the differentiated phenotype of pig articular chondrocytes in culture. J Cell Sci 89 (Pt 3), 373, 1988.
    • (1988) J Cell Sci , vol.89 , Issue.PART 3 , pp. 373
    • Watt, F.M.1
  • 41
    • 0035497425 scopus 로고    scopus 로고
    • Boundary lubrication by lubricin is mediated by O-linked beta(1-3)Gal-GalNAc oligosaccharides
    • Jay, G.D., Harris, D.A., and Cha, C.J. Boundary lubrication by lubricin is mediated by O-linked beta(1-3)Gal-GalNAc oligosaccharides. Glycoconj J 18, 807, 2001.
    • (2001) Glycoconj J , vol.18 , pp. 807
    • Jay, G.D.1    Harris, D.A.2    Cha, C.J.3
  • 43
    • 67650738583 scopus 로고    scopus 로고
    • Activation and dedifferentiation of chondrocytes: Implications in cartilage injury and repair
    • Schulze-Tanzil, G. Activation and dedifferentiation of chondrocytes: implications in cartilage injury and repair. Ann Anat 191, 325, 2009.
    • (2009) Ann Anat , vol.191 , pp. 325
    • Schulze-Tanzil, G.1
  • 44
    • 70350493796 scopus 로고    scopus 로고
    • Zonal chondrocytes seeded in a layered agarose hydrogel create engineered cartilage with depth-dependent cellular and mechanical inhomogeneity
    • Ng, K.W., Ateshian, G.A., and Hung, C.T. Zonal chondrocytes seeded in a layered agarose hydrogel create engineered cartilage with depth-dependent cellular and mechanical inhomogeneity. Tissue Eng Part A 15, 2315, 2009.
    • (2009) Tissue Eng Part A , vol.15 , pp. 2315
    • Ng, K.W.1    Ateshian, G.A.2    Hung, C.T.3
  • 45
    • 0035674325 scopus 로고    scopus 로고
    • Effect of oxygen tension and alginate encapsulation on restoration of the differentiated phenotype of passaged chondrocytes
    • Murphy, C.L., and Sambanis, A. Effect of oxygen tension and alginate encapsulation on restoration of the differentiated phenotype of passaged chondrocytes. Tissue Eng 7, 791, 2001.
    • (2001) Tissue Eng , vol.7 , pp. 791
    • Murphy, C.L.1    Sambanis, A.2
  • 46
    • 2542554971 scopus 로고    scopus 로고
    • Loss of chondrogenic potential in dedifferentiated chondrocytes correlates with deficient Shc-Erk interaction and apoptosis
    • Schulze-Tanzil, G., Mobasheri, A., de Souza, P., John, T., and Shakibaei, M. Loss of chondrogenic potential in dedifferentiated chondrocytes correlates with deficient Shc-Erk interaction and apoptosis. Osteoarthritis Cartilage 12, 448, 2004.
    • (2004) Osteoarthritis Cartilage , vol.12 , pp. 448
    • Schulze-Tanzil, G.1    Mobasheri, A.2    De Souza, P.3    John, T.4    Shakibaei, M.5
  • 48
    • 77956882362 scopus 로고    scopus 로고
    • Oxygen tension differentially regulates the functional properties of cartilaginous tissues engineered from infrapatellar fat pad derived MSCs and articular chondrocytes
    • Buckley, C.T., Vinardell, T., and Kelly, D.J. Oxygen tension differentially regulates the functional properties of cartilaginous tissues engineered from infrapatellar fat pad derived MSCs and articular chondrocytes. Osteoarthritis Cartilage 18, 1345, 2010.
    • (2010) Osteoarthritis Cartilage , vol.18 , pp. 1345
    • Buckley, C.T.1    Vinardell, T.2    Kelly, D.J.3
  • 49
    • 49149126749 scopus 로고    scopus 로고
    • Tensile properties of engineered cartilage formed from chondrocyte-and MSC-laden hydrogels
    • Huang, A.H., Yeger-McKeever, M., Stein, A., and Mauck, R.L. Tensile properties of engineered cartilage formed from chondrocyte-and MSC-laden hydrogels. Osteoarthritis Cartilage 16, 1074, 2008.
    • (2008) Osteoarthritis Cartilage , vol.16 , pp. 1074
    • Huang, A.H.1    Yeger-Mckeever, M.2    Stein, A.3    Mauck, R.L.4
  • 50
    • 73649122403 scopus 로고    scopus 로고
    • Gelatin hydrogel prepared by photo-initiated polymerization and loaded with TGF-beta1 for cartilage tissue engineering
    • Hu, X., Ma, L., Wang, C., and Gao, C. Gelatin hydrogel prepared by photo-initiated polymerization and loaded with TGF-beta1 for cartilage tissue engineering. Macromol Biosci 9, 1194, 2009.
    • (2009) Macromol Biosci , vol.9 , pp. 1194
    • Hu, X.1    Ma, L.2    Wang, C.3    Gao, C.4
  • 51
    • 78650308613 scopus 로고    scopus 로고
    • Effects of TGFbeta1 on alternative splicing of superficial zone protein in articular cartilage cultures
    • DuRaine, G.D., Chan, S.M., and Reddi, A.H. Effects of TGFbeta1 on alternative splicing of superficial zone protein in articular cartilage cultures. Osteoarthritis Cartilage 19, 103, 2011.
    • (2011) Osteoarthritis Cartilage , vol.19 , pp. 103
    • Duraine, G.D.1    Chan, S.M.2    Reddi, A.H.3
  • 53
    • 0141750631 scopus 로고    scopus 로고
    • Cyclic tensile strain and cyclic hydrostatic pressure differentially regulate expression of hypertrophic markers in primary chondrocytes
    • Wong, M., Siegrist, M., and Goodwin, K. Cyclic tensile strain and cyclic hydrostatic pressure differentially regulate expression of hypertrophic markers in primary chondrocytes. Bone 33, 685, 2003.
    • (2003) Bone , vol.33 , pp. 685
    • Wong, M.1    Siegrist, M.2    Goodwin, K.3
  • 55
    • 34248144804 scopus 로고    scopus 로고
    • Identification of superficial zone articular chondrocyte stem/progenitor cells
    • Hattori, S., Oxford, C., and Reddi, A.H. Identification of superficial zone articular chondrocyte stem/progenitor cells. Biochem Biophys Res Commun 358, 99, 2007.
    • (2007) Biochem Biophys Res Commun , vol.358 , pp. 99
    • Hattori, S.1    Oxford, C.2    Reddi, A.H.3
  • 56
    • 77956239114 scopus 로고    scopus 로고
    • MicroRNA-221 regulates chondrogenic differentiation through promoting proteosomal degradation of slug by targeting Mdm2
    • Kim, D., Song, J., and Jin, E.J. MicroRNA-221 regulates chondrogenic differentiation through promoting proteosomal degradation of slug by targeting Mdm2. J Biol Chem 285, 26900, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 26900
    • Kim, D.1    Song, J.2    Jin, E.J.3
  • 57
    • 79751474246 scopus 로고    scopus 로고
    • The microRNA expression profiles of mouse mesenchymal stem cell during chondrogenic differentiation
    • Yang, B., Guo, H., Zhang, Y., Dong, S., and Ying, D. The microRNA expression profiles of mouse mesenchymal stem cell during chondrogenic differentiation. BMB Rep 44, 28, 2011
    • (2011) BMB Rep , vol.44 , pp. 28
    • Yang, B.1    Guo, H.2    Zhang, Y.3    Dong, S.4    Ying, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.