Effects of TGF-β1 on alternative splicing of Superficial Zone Protein in articular cartilage cultures

Osteoarthritis and Cartilage

Volumn 19, Issue 1, 2011, Pages 103-110

  DuRaine, G D ^a   Chan, S M T ^a   Reddi, A H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alternative splicing; Articular cartilage; Superficial Zone Protein (SZP); TGF

Indexed keywords

HEPARIN; PROTEIN; RECOMBINANT PROTEIN; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; RNA; SMAD3 PROTEIN; SUPERFICIAL ZONE PROTEIN; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CATTLE; CELL CULTURE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMUR CONDYLE; KNEE; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALTERNATIVE SPLICING; ANIMALS; CARTILAGE, ARTICULAR; CATTLE; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXONS; GLYCOPROTEINS; IMMUNOBLOTTING; KNEE JOINT; MEMBRANE PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA1; WEIGHT-BEARING;

EID: 78650308613     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2010.10.008     Document Type: Article

References (31)

1. Flannery C.R., Hughes C.E., Schumacher B.L., Tudor D., Aydelotte M.B., Kuettner K.E., et al. Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and Is a multifunctional proteoglycan with potential growth-promoting, cytoprotective, and lubricating properties in cartilage metabolism. Biochem Biophys Res Commun 1999, 254(3):535-541.
2. Ikegawa S., Sano M., Koshizuka Y., Nakamura Y. Isolation, characterization and mapping of the mouse and human PRG4 (proteoglycan 4) genes. Cytogenet Cell Genet 2000, 90(3-4):291-297.
3. Jay G.D., Tantravahi U., Britt D.E., Barrach H.J., Cha C.J. Homology of lubricin and superficial zone protein (SZP): products of megakaryocyte stimulating factor (MSF) gene expression by human synovial fibroblasts and articular chondrocytes localized to chromosome 1q25. J Orthop Res 2001, 19(4):677-687.
4. Liu Y.J., Lu S.H., Xu B., Yang R.C., Ren Q., Liu B., et al. Hemangiopoietin, a novel human growth factor for the primitive cells of both hematopoietic and endothelial cell lineages. Blood 2004, 103(12):4449-4456.
5. Swann D.A., Hendren R.B., Radin E.L., Sotman S.L., Duda E.A. The lubricating activity of synovial fluid glycoproteins. Arthritis Rheum 1981, 24(1):22-30.
6. Jay G.D., Torres J.R., Warman M.L., Laderer M.C., Breuer K.S. The role of lubricin in the mechanical behavior of synovial fluid. Proc Natl Acad Sci U S A 2007, 104(15):6194-6199.
7. Jay G.D., Britt D.E., Cha C.J. Lubricin is a product of megakaryocyte stimulating factor gene expression by human synovial fibroblasts. J Rheumatol 2000, 27(3):594-600.
8. Rhee D.K., Marcelino J., Baker M., Gong Y., Smits P., Lefebvre V., et al. The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth. J Clin Invest 2005, 115(3):622-631.
9. Jay G.D., Harris D.A., Cha C.J. Boundary lubrication by lubricin is mediated by O-linked beta(1-3)Gal-GalNAc oligosaccharides. Glycoconj J 2001, 18(10):807-815.
10. Neu C.P., Khalafi A., Komvopoulos K., Schmid T.M., Reddi A.H. Mechanotransduction of articular cartilage superficial zone protein by TGF-β signaling. Arthritis Rheum 2007, 56(11):3706-3714.
11. Duraine G., Neu C.P., Chan S.M., Komvopoulos K., June R.K., Reddi A.H. Regulation of the friction coefficient of articular cartilage by TGF-beta1 and IL-1beta. J Orthop Res 2008, 27:249-256.
12. Zappone B., Ruths M., Greene G.W., Jay G.D., Israelachvili J.N. Adsorption, lubrication, and wear of lubricin on model surfaces: polymer brush-like behavior of a glycoprotein. Biophys J 2007, 92(5):1693-1708.
13. Niikura T., Reddi A.H. Differential regulation of lubricin/superficial zone protein by transforming growth factor beta/bone morphogenetic protein superfamily members in articular chondrocytes and synoviocytes. Arthritis Rheum 2007, 56(7):2312-2321.
14. Fisher J.P., Jo S., Mikos A.G., Reddi A.H. Thermoreversible hydrogel scaffolds for articular cartilage engineering. J Biomed Mater Res A 2004, 71(2):268-274.
15. Bubner B., Gase K., Baldwin I.T. Two-fold differences are the detection limit for determining transgene copy numbers in plants by real-time PCR. BMC Biotechnol 2004, 4:14.
16. Han F., Gilbert J.R., Harrison G., Adams C.S., Freeman T., Tao Z., et al. Transforming growth factor-beta1 regulates fibronectin isoform expression and splicing factor SRp40 expression during ATDC5 chondrogenic maturation. Exp Cell Res 2007, 313(8):1518-1532.
17. Schumacher B.L., Block J.A., Schmid T.M., Aydelotte M.B., Kuettner K.E. A novel proteoglycan synthesized and secreted by chondrocytes of the superficial zone of articular cartilage. Arch Biochem Biophys 1994, 311(1):144-152.
18. Su J.L., Schumacher B.L., Lindley K.M., Soloveychik V., Burkhart W., Triantafillou J.A., et al. Detection of superficial zone protein in human and animal body fluids by cross-species monoclonal antibodies specific to superficial zone protein. Hybridoma 2001, 20(3):149-157.
19. Tojo M., Hamashima Y., Hanyu A., Kajimoto T., Saitoh M., Miyazono K., et al. The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta. Cancer Sci 2005, 96(11):791-800.
20. Qureshi H.Y., Ricci G., Zafarullah M. Smad signaling pathway is a pivotal component of tissue inhibitor of metalloproteinases-3 regulation by transforming growth factor beta in human chondrocytes. Biochim Biophys Acta 2008, 1783(9):1605-1612.
21. Jones A.R., Gleghorn J.P., Hughes C.E., Fitz L.J., Zollner R., Wainwright S.D., et al. Binding and localization of recombinant lubricin to articular cartilage surfaces. J Orthop Res 2007, 25(3):283-292.
22. Grad S., Lee C.R., Wimmer M.A., Alini M. Chondrocyte gene expression under applied surface motion. Biorheology 2006, 43(3-4):259-269.
23. Sun Y., Berger E.J., Zhao C., Jay G.D., An K.N., Amadio P.C. Expression and mapping of lubricin in canine flexor tendon. J Orthop Res 2006, 24(9):1861-1868.
24. Nugent G.E., Aneloski N.M., Schmidt T.A., Schumacher B.L., Voegtline M.S., Sah R.L. Dynamic shear stimulation of bovine cartilage biosynthesis of proteoglycan 4. Arthritis Rheum 2006, 54(6):1888-1896.
25. Villiger P.M., Lotz M. Differential expression of TGF beta isoforms by human articular chondrocytes in response to growth factors. J Cell Physiol 1992, 151(2):318-325.
26. Kim S.J., Angel P., Lafyatis R., Hattori K., Kim K.Y., Sporn M.B., et al. Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex. Mol Cell Biol 1990, 10(4):1492-1497.
27. Kim S.J., Jeang K.T., Glick A.B., Sporn M.B., Roberts A.B. Promoter sequences of the human transforming growth factor-beta 1 gene responsive to transforming growth factor-beta 1 autoinduction. J Biol Chem 1989, 264(12):7041-7045.
28. Marcelino J., Carpten J.D., Suwairi W.M., Gutierrez O.M., Schwartz S., Robbins C., et al. CACP, encoding a secreted proteoglycan, is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Nat Genet 1999, 23(3):319-322.
29. Zappone B., Greene G.W., Oroudjev E., Jay G.D., Israelachvili J.N. Molecular aspects of boundary lubrication by human lubricin: effect of disulfide bonds and enzymatic digestion. Langmuir 2008, 24(4):1495-1508.
30. Gleghorn J.P., Jones A.R., Flannery C.R., Bonassar L.J. Boundary mode lubrication of articular cartilage by recombinant human lubricin. J Orthop Res 2008, 27:771-777.
31. Stamm S. Regulation of alternative splicing by reversible protein phosphorylation. J Biol Chem 2008, 283(3):1223-1227.