Boundary lubrication by lubricin is mediated by O-linked β(1-3)Gal-GalNAc oligosaccharides

Glycoconjugate Journal

Volumn 18, Issue 10, 2001, Pages 807-815

  Jay, Gregory D ^a,b   Harris, Darcy A ^a   Cha, Chung Ja ^a  

^a BROWN UNIVERSITY   (United States)

^b Brown University   (United States)

Author keywords

Lubrication; Lubricin; Megakaryocyte stimulating factor; Synovial fluid

Indexed keywords

ALPHA N ACETYLGALACTOSAMINIDASE; BETA GALACTOSIDASE; GENE PRODUCT; GLYCOPROTEIN; GLYCOSIDASE; LATEX; LUBRICIN; N ACETYLGALACTOSAMINE; OLIGOSACCHARIDE; SIALIDASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CARTILAGE; CATTLE; CONTROLLED STUDY; ELECTROPHORESIS; FRICTION; GLYCOSYLATION; HUMAN; HUMAN TISSUE; LUBRICATION; MEGAKARYOCYTE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROCESSING; SYNOVIAL FLUID;

ACETYLGALACTOSAMINE; ANIMALS; CATTLE; ELECTROPHORESIS; FLUORESCENT DYES; GALACTOSE; GLYCOPROTEINS; GLYCOSYLATION; HEXOSAMINIDASES; HUMANS; LUBRICATION; OLIGOSACCHARIDES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; SYNOVIAL MEMBRANE;

ANIMALIA; BOS TAURUS; BOVINAE; MAMMALIA;

EID: 0035497425     PISSN: 02820080     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021159619373     Document Type: Article

References (29)

1. Swann DA, Sotman S, Dixon M, Brooks C, The isolation and partial characterization of the major glycoprotein (LGP-1) from the articular lubricating fraction from bovine synovial fluid, Biochem J 161, 473-85 (1977).
2. Jay GD, Britt D, Cha CJ, Lubricin is a product of megakaryocyte stimulating factor (MSF) gene expression by synovial fibroblasts, J Rheumatol 27, 594-600 (2000).
3. Flannery CR, Hughes CR, Schumacher BL, Tudor D, Aydelotte MB, Kuettner KE, Caterson B, Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and is a multifunctional proteoglycan with potential growth-promoting, cytoprotective and lubricating properties in cartilage metabolism, Biochem Biophys Res Comm 234, 535-41 (1999).
4. Jay GD, Tantravahi U, Britt D, Barrach HJ, Cha CJ, Homology of lubricin and superficial zone protein (SZP): Products of megakaryocyte stimulating factor (MSF) gene expression by human synovial fibroblasts and articular chondrocytes localized to chromosome 1q25, J Orthop Res 19, 677-87 (2001).
5. Marcelino J, Carpten JD, Suwairi WM, et al., CACP, encoding a secreted proteoglycan, is mutated in camptodactyl-arthropathycoxa vara-pericarditis syndrome, Nature Genet 23, 319-22 (1999).
6. Bahabri SA, Suwairi WM, Laxer RM, Polinkovsky A, Dalaan AA, Warman ML, The camptodactyl-arthropathy-coxa varapericarditis syndrome, Arthritis Rheum 41, 730-5 (1998).
7. Jay GD, Characterization of a bovine synovial fluid lubricating factor. I. Chemical, surface activity and lubricating properties, Conn Tiss Res 28, 71-88 (1992).
8. McCutchen CW, Boundary lubrication by synovial fluid: Demonstration and possible osmotic explanation, Fed Proc Fed Am Soc Exp Biol 25, 1061-8 (1966).
9. Swann DA, Slayter HS, Silver FH, The molecular structure of lubricating glycoprotein-I, the boundary lubricant for articular cartilage, J Biol Chem 256, 5921-5 (1981).
10. Prakobphol A, Levine M, Tabak L, Reddy M, Purification of a low-molecular-weight, mucin-type glycoprotein from human submandibular-sublingual saliva, Carbohydrate Res 108, 111-22 (1982).
11. Swann DA, Personal communication (1988).
12. Starr CM, Masada I, Hague C, Skop E, Lock JC, Fluorophore-assisted carbohydrate electrophoresis the separation, analysis, and sequencing of carbohydrates, J Chromatography A 720, 295-321 (1996).
13. Davis WH, Lee SL, Sokoloff L, A proposed model of boundary lubrication synovial fluid: Structuring of boundary water, J Biomech Eng 101, 185-92 (1979).
14. Wilkins JF, Proteolytic destruction of synovial boundary lubrication, Nature 219, 1050-1 (1968).
15. Reimann I, Stougaard J, Northeved A, Johnsen SJ, Demonstration of boundary lubrication by synovial fluid, Acta Orthop Scand 46, 1-10 (1975).
16. McCutchen CW, The frictional properties of animal joints, Wear 5, 412-5 (1962).
17. Jay GD, Haberstroh K, Cha CJ, Comparison of the boundary lubricating ability of bovine synovial fluid, lubricin and healon, J Biomed Mater Res 40, 414-8 (1998).
18. Umemoto J, Bhavanandan VP, Davidson EA, Purification and properties of an endo-α-N-galactosaminidase from Diploococcus pneumoniae, J Biol Chem 23, 8609-14 (1977).
19. Jay GD, B-S Hong, Characterization of a bovine synovial fluid lubricating factor. II comparison with purified ocular and salivary mucin, Conn Tissue Res 28, 89-98 (1992).
20. Komatso SK, Devries AL, Feeney RE, Studies of the Structure of Freezing Point-depressing Slycoproteins from an Antarctic Fish, 245, 2909-13 (1970).
21. Garg HG, Swann DA, Glasgow LR, The structure of the O-glycosylically-linked oligosaccharide chains of LPG-1, a glycoprotein present in articular lubricating fraction of bovine synovial fluid, Carbohyd Res 78, 79-88 (1979).
22. Merberg DM, Fitz LJ, Temple P, et al., A comparison of vitronectin and megakaryocyte stimulating factor. In Biology of Vitronectins and Their Receptors (Elsevier, Philadelphia, 1992), pp. 45-52.
23. Hansen JE, Lund O, Tolstrup N, Gooley AA, Williams KL, Brunak S, NetOglyc: Prediction of mucin type O-glycosylation sites based on sequence context and surface accessibility, Glycoconjugate J 15, 115-30 (1998).
24. Hills BA, Monds MK, Enzymatic identifications of the load-bearing boundary lubricant in the joint, Br J Rheumatol 37, 137-42 (1998).
25. Jay GD, Cha CJ, The effect of phospholipase digestion upon the boundary lubricating ability of synovial fluid, J Rheumatol 26, 2454-7 (1999).
26. Guerra D, Frizziero L, Losi M, Bacchelli B, Mezzadri G, Pasquali-Ronchetti I, Ultrastructural identification of a membrane-like structure on the surface of normal articular cartilage, J Submicrosc Cytol Pathol 28, 385-93 (1996).
27. Chappuis J, Sherman IA, Neumann AW, Surface tension of animal cartilage as it relates to friction in joints, Ann Biomed Eng 11, 435-49 (1983).
28. Kobayashi M, Toguchida J, Oka M, Study on the lubrication mechanism of natural joints by confocal laser scanning microscopy, J Biomed Mater Res 55, 645-51 (2001).
29. Denny P, Denny P, Hong-Le N, Characterization of asparagine-linked oigosaccharides on a mouse submandibular mucin, Glycobiology 5, 589-97 (1996).