Related F-box proteins control cell death in caenorhabditis elegans and human lymphoma

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 10, 2013, Pages 3943-3948

  Chiorazzi, Michael ^a   Rui, Lixin ^b   Yang, Yandan ^b   Ceribelli, Michele ^b   Tishbi, Nima ^a   Maurer, Carine W ^a   Ranuncolo, Stella M ^b   Zhao, Hong ^b   Xu, Weihong ^b   Chan, Wing Chung C ^c   Jaffe, Elaine S ^b   Gascoyne, Randy D ^d   Campo, Elias ^e   Rosenwald, Andreas ^f   Ott, German ^g   Delabie, Jan ^h   Rimsza, Lisa M ^i,j   Shaham, Shai ^a   Staudt, Louis M ^b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

^d BRITISH COLUMBIA CANCER AGENCY   (Canada)

^e UNIVERSITY OF BARCELONA   (Spain)

^f UNIVERSITY OF WÜRZBURG   (Germany)

^g DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^h OSLO UNIVERSITY HOSPITAL   (Norway)

ⁱ UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^j Southwest Oncology Group   (United States)

more..

Author keywords

Cancer; Ubiquitin

Indexed keywords

CASPASE; DRE 1 PROTEIN; F BOX PROTEIN; MESSENGER RNA; PROTEIN BCL 2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CELL DEATH; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; IN VIVO STUDY; LARGE CELL LYMPHOMA; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CASPASES; CELL LINE, TUMOR; ENZYME ACTIVATION; F-BOX PROTEINS; HEK293 CELLS; HUMANS; LYMPHOMA; LYMPHOMA, LARGE B-CELL, DIFFUSE; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PROTO-ONCOGENE PROTEINS C-BCL-2; REPRESSOR PROTEINS; RNA, MESSENGER; RNA, NEOPLASM; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84874641177     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1217271110     Document Type: Article

References (34)

1. Dawson TM, Ko HS, Dawson VL (2010) Genetic animal models of Parkinson's disease. Neuron 66(5):646-661.
2. Heintz N, Zoghbi HY (2000) Insights from mouse models into the molecular basis of neurodegeneration. Annu Rev Physiol 62:779-802.
3. Davies SW, et al. (1997) Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell 90(3):537-548.
4. Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100(1):57-70.
5. Strasser A, Harris AW, Cory S (1991) bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 67(5):889-899.
6. Vaux DL, Cory S, Adams JM (1988) Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335(6189):440-442.
7. Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz HR (1993) The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell 75(4):641-652.
8. Liu X, Kim CN, Yang J, Jemmerson R, Wang X (1996) Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c. Cell 86(1):147-157.
9. Abraham MC, Shaham S (2004) Death without caspases, caspases without death. Trends Cell Biol 14(4):184-193.
10. Maurer CW, Chiorazzi M, Shaham S (2007) Timing of the onset of a developmental cell death is controlled by transcriptional induction of the C. elegans ced-3 caspaseencoding gene. Development 134(7):1357-1368.
11. Conradt B (2009) Genetic control of programmed cell death during animal development. Annu Rev Genet 43:493-523.
12. Sulston JE, Schierenberg E, White JG, Thomson JN (1983) The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev Biol 100(1):64-119.
13. Fielenbach N, et al. (2007) DRE-1: An evolutionarily conserved F box protein that regulates C. elegans developmental age. Dev Cell 12(3):443-455.
14. Hsu DR, Chuang PT, Meyer BJ (1995) DPY-30, a nuclear protein essential early in embryogenesis for Caenorhabditis elegans dosage compensation. Development 121(10):3323-3334.
15. Ellis RE, Horvitz HR (1991) Two C. elegans genes control the programmed deaths of specific cells in the pharynx. Development 112(2):591-603.
16. Ellis RE, Jacobson DM, Horvitz HR(1991) Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans. Genetics 129(1):79-94.
17. Li S, et al. (2004) A map of the interactome network of the metazoan C. elegans. Science 303(5657):540-543.
18. Killian DJ, et al. (2008) SKR-1, a homolog of Skp1 and a member of the SCF(SEL-10) complex, regulates sex-determination and LIN-12/Notch signaling in C. elegans. Dev Biol 322(2):322-331.
19. Shaffer AL, Young RM, Staudt LM (2012) Pathogenesis of human B cell lymphomas. Annu Rev Immunol 30:565-610.
20. Duan S, et al. (2012) FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas. Nature 481(7379):90-93.
21. Ci W, et al. (2009) The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL. Blood 113(22):5536-5548.
22. Saito M, et al. (2009) BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma. Proc Natl Acad Sci USA 106(27):11294-11299.
23. Alizadeh AA, et al. (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403(6769):503-511.
24. Abecasis GR, et al.; 1000 Genomes Project Consortium (2010) A map of human genome variation from population-scale sequencing. Nature 467(7319):1061-1073.
25. Tennessen JA, et al.; Broad GO; Seattle GO; NHLBI Exome Sequencing Project (2012) Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science 337(6090):64-69.
26. Akiyama T, et al. (2003) Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim. EMBO J 22(24):6653-6664.
27. Ley R, Balmanno K, Hadfield K, Weston C, Cook SJ (2003) Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. J Biol Chem 278(21):18811-18816.
28. Tait SW, et al. (2007) Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment. J Cell Biol 179(7):1453-1466.
29. Zhong Q, Gao W, Du F, Wang X (2005) Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. Cell 121(7):1085- 1095.
30. Basu A, Haldar S (2002) Signal-induced site specific phosphorylation targets Bcl2 to the proteasome pathway. Int J Oncol 21(3):597-601.
31. Breitschopf K, Haendeler J, Malchow P, Zeiher AM, Dimmeler S (2000) Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: Molecular characterization of the involved signaling pathway. Mol Cell Biol 20(5): 1886-1896.
32. Dimmeler S, Breitschopf K, Haendeler J, Zeiher AM (1999) Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: A link between the apoptosome and the proteasome pathway. J Exp Med 189(11):1815-1822.
33. Lin SS, et al. (2006) PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum. J Biol Chem 281(32):23003-23012.
34. Chleq-Deschamps CM, et al. (1993) Topographical dissociation of BCL-2 messenger RNA and protein expression in human lymphoid tissues. Blood 81(2):293-298.