Pharmacokinetics, bioavailability, and metabolism of 2,3,5,4′- tetrahydroxystilbene-2-O-β-D-glucoside in rats by ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry and high-performance liquid chromatography-ultraviolet detection

Journal of Liquid Chromatography and Related Technologies

Volumn 36, Issue 6, 2013, Pages 717-730

  Zhao, Ying Yong ^a   Cheng, Xian Long ^b   Wei, Feng ^b   Han, Xiao Qiang ^c   Xiao, Xin Yue ^b   Lin, Rui Chao ^b  

^a NORTHWEST UNIVERSITY   (China)

^b NATIONAL INSTITUTES FOR FOOD AND DRUG CONTROL   (China)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

2,3,5,4 tetrahydroxystilbene 2 O D glucoside; bioavailability; metabolism; pharmacokinetics; Polygoni multiflori; UPLC Q TOF MS

Indexed keywords

ANTI-INFLAMMATORIES; ANTITUMOR PROPERTY; BIOAVAILABILITY; HEPATOPROTECTIVE; HPLC-UV; LIQUID CHROMATOGRAPHY-QUADRUPOLE TIME-OF-FLIGHT MASS SPECTROMETRIES; MEDICAL HERBS; NATURAL PRODUCTS; ORAL ADMINISTRATION; PHARMACOLOGICAL ACTIVITY; POLYGONI MULTIFLORI; RAT PLASMA; TOTAL RECOVERY; ULTRA VIOLET DETECTION; UPLC-Q-TOF/MS;

BIOCHEMISTRY; BODY FLUIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLISM; PHARMACOKINETICS; PHYSIOLOGY; RATS;

CHROMATOGRAPHY;

2,3,5,4' TETRAHYDROXYSTILBENE 2 O BETA D GLUCOSIDE; CHINESE DRUG; GLUCOSIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DRUG ABSORPTION; DRUG BILE LEVEL; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG FECES LEVEL; DRUG METABOLISM; DRUG STRUCTURE; DRUG URINE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; RAT; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 84874637430     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826076.2012.673209     Document Type: Article

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