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Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 21, 2011, Pages 1945-1953

Pharmacokinetics of ergosterol in rats using rapid resolution liquid chromatography-atmospheric pressure chemical ionization multi-stage tandem mass spectrometry and rapid resolution liquid chromatography/tandem mass spectrometry

(9) Zhao, Ying Yong a Cheng, Xian Long b Liu, Rui b Ho, Charlene C c Wei, Feng b Yan, Sui Hong a Lin, Rui Chao a,b Zhang, Yongmin d Sun, Wen Ji a

a NORTHWEST UNIVERSITY (China)

b NATIONAL INSTITUTE FOR THE CONTROL OF PHARMACEUTICAL AND BIOLOGICAL PRODUCTS (China)

c UNIVERSITY OF CALIFORNIA (United States)

d SORBONNE UNIVERSITÉ (France)

Author keywords

Elimination pathway; Ergosterol; Metabolite; Pharmacokinetics; RRLC APCI MS MS; RRLC DAD APCI MSn

Indexed keywords

AGILENT; ATMOSPHERIC PRESSURE CHEMICAL IONIZATION MASS SPECTROMETRY; CHEMICAL IONIZATION; CONCENTRATION RANGES; ELIMINATION PATHWAY; ERGOSTEROL; LINEAR CALIBRATION CURVE; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; MOBILE PHASE; MULTI-STAGE; MULTI-STAGE MASS SPECTROMETRY; MULTIPLE REACTION MONITORING; PHARMACOKINETIC PROPERTIES; POSITIVE ION MODE; RAPID RESOLUTION; RAT PLASMA; RRLC-APCI-MS/MS; RRLC-DAD-APCI-MSN; TANDEM MASS SPECTROMETRY;

ATMOSPHERIC CHEMISTRY; ATMOSPHERIC IONIZATION; ATMOSPHERIC PRESSURE; BIOMOLECULES; BODY FLUIDS; CHEMICAL DETECTION; FORMIC ACID; IONIZATION OF LIQUIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METABOLITES; METHANOL; PHARMACOKINETICS; RATS;

LIQUIDS;

DRUG METABOLITE; ERGOSTEROL; FORMIC ACID; METHANOL; WATER;

ANIMAL EXPERIMENT; ARTICLE; ATMOSPHERIC PRESSURE; IONIZATION; LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY;

ANIMALS; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; ERGOSTEROL; FECES; LEAST-SQUARES ANALYSIS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 79959326346 PISSN: 15700232 EISSN: 1873376X Source Type: Journal
DOI: 10.1016/j.jchromb.2011.05.025 Document Type: Article

Times cited : (29)

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