A fast and sensitive HPLC-MS/MS analysis and preliminary pharmacokinetic characterization of ergone in rats

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 1, 2009, Pages 29-33

  Zhao, Ying yong ^a   Cheng, Xian long ^b   Zhang, Yongmin ^c   Chao, Xu ^a   Zhao, Ye ^a   Lin, Rui chao ^a,b   Sun, Wen ji ^a  

^a NORTHWEST UNIVERSITY   (China)

^b NATIONAL INSTITUTE FOR THE CONTROL OF PHARMACEUTICAL AND BIOLOGICAL PRODUCTS   (China)

^c SORBONNE UNIVERSITÉ   (France)

Author keywords

Ergosta 4,6,8(14),22 tetraen 3 one; HPLC APCI MS MS; Pharmacokinetics

Indexed keywords

CHROMATOGRAPHIC SEPARATIONS; CONCENTRATION RANGES; ERGOSTA-4,6,8(14),22-TETRAEN-3-ONE; HPLC-MS/MS; INTERNAL STANDARDS; LIMIT OF DETECTION; MIXED SOLUTION; MOBILE PHASE; PHARMACOKINETIC STUDIES; PLASMA SAMPLES; RAT PLASMA; SUPERNATANTS;

ACETONE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHANOL; ORGANIC ACIDS; PHARMACOKINETICS; RATS;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

ESRGOSTA 4,6,8(14),22 TETRAEN 3 ONE; STEROID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD ANALYSIS; CHEMICAL STRUCTURE; CHROMATOGRAPHY; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; ERGOSTEROL; LEAST-SQUARES ANALYSIS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 71149118225     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.11.013     Document Type: Article

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