Discrimination of isobaric Leu/Ile residues by MALDI in-source decay mass spectrometry

Journal of the American Society for Mass Spectrometry

Volumn 24, Issue 2, 2013, Pages 297-300

  Asakawa, Daiki ^a,b   Smargiasso, Nicolas ^a   De Pauw, Edwin ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

1,5 Diaminonapthalene; Initial velocity; Negative ion mode; Side chain loss; Top down sequencing

Indexed keywords

1,5-DIAMINONAPTHALENE; INITIAL VELOCITIES; NEGATIVE-ION MODE; SIDE-CHAINS; TOPDOWN;

AMINO ACIDS; DISSOCIATION; MASS SPECTROMETRY;

PROTEINS;

1,5 DIAMINONAPHTHALENE; ISOLEUCINE; LEUCINE; NAPHTHALENE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; HYDROGEN BOND; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION IN SOURCE MASS SPECTROMETRY; PROTEIN CLEAVAGE; REACTION ANALYSIS; SEQUENCE ANALYSIS;

2-NAPHTHYLAMINE; GENTISATES; ISOLEUCINE; LEUCINE; MODELS, MOLECULAR; MYOGLOBIN; ORTHO-AMINOBENZOATES; SEQUENCE ANALYSIS, PROTEIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84874612107     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-012-0523-7     Document Type: Article

References (19)

1. Paizs, B.; Suhai, S.: Fragmentation pathways of protonated peptides. Mass Spectrom. Rev. 24, 508-548 (2005)
2. Johnson, R.S.; Martin, S.A.; Biemann, K.; Stults, J.T.; Watson, J.T.: Novel fragmentation process of peptides by collision-induced decomposition in a tandem mass spectrometer: differentiation of leucine and isoleucine. Anal. Chem. 59, 2621-2625 (1987)
3. Zubarev, R.A.: Reactions of polypeptide ions with electrons in the gas phase. Mass Spectrom. Rev. 22, 57-77 (2003)
4. Syka, J.E.; Coon, J.J.; Schroeder, M.J.; Shabanovitz, J.; Hunt, D.F.: Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry. Proc. Natl. Acad. Sci. U.S.A. 101, 9528-9533 (2004)
5. Kjeldsen, F.; Haselmann, K.F.; Sørensen, E.S.; Zubarev, R.A.: Distinguishing of Ile/Leu amino acid residues in the pp 3 protein by (hot) electron capture dissociation in fourier transform ion cyclotron resonance mass spectrometry. Anal. Chem. 75, 1267-1274 (2003)
6. Han, H.; Xia, Y.; McLuckey, S.A.: Ion trap collisional activation of c and z• Ions Formed via Gas-Phase Ion/Ion Electron-Transfer Dissociation. J. Proteome Res. 6, 3062-3069 (2007)
7. Chung, T.W.; Tureček, F.: Backbone and side-chain specific dissociations of z ions from non-tryptic peptides. J. Am. Soc. Mass Spectrom. 21, 1279-1295 (2010)
8. α bond cleavage of the peptide backbone via hydrogen abstraction. J. Am. Soc. Mass Spectrom. 12, 1044-1049 (2001)
9. Köcher, T.; Engström, Å.; Zubarev, R.A.: Fragmentation of peptides in MALDI in-source decay mediated by hydrogen radicals. Anal. Chem. 77, 172-177 (2005)
10. Hardouin, J.: Protein sequence information by matrix-assisted laser desorption/ionization in-source decay mass spectrometry. Mass Spectrom. Rev. 26, 672-682 (2007)
11. Sellami, L.; Belgacem, O.; Villard, C.; Openshaw, M.E.; Barbier, P.; Lafitte, D.: In-source decay and pseudo tandem mass spectrometry fragmentation processes of entire high mass proteins on a hybrid vacuum matrix-assisted laser desorption ionization-quadrupole ion-trap time-of-flight mass spectrometer. Anal. Chem. 84, 5180-5185 (2012)
12. Soltwisch, J.; Dreisewerd, K.: Discrimination of isobaric leucine and isoleucine residues and analysis of post-translational modifications in peptides by MALDI in-source decay mass spectrometry combined with collisional cooling. Anal. Chem. 82, 5628-5635 (2010)
13. Demeure, K.; Quinton, L.; Gabelica, V.; De Pauw, E.: Rational selection of the optimum MALDI matrix for top-down proteomics by in-source decay. Anal. Chem. 79, 8678-8685 (2007)
14. Smargiasso, N.; Quinton, L.; De Pauw, E.: 2-Aminobenzamide and 2-aminobenzoic acid as new MALDI matrices inducing radical mediated in-source decay of peptides and proteins. J. Am. Soc. Mass Spectrom. 23, 469-474 (2012)
15. Demeure, K.; Gabelica, V.; De Pauw, E.: New advances in the understanding of the in-source decay fragmentation of peptides in MALDI-TOF-MS. J. Am. Soc. Mass Spectrom. 21, 1906-1917 (2010)
16. Spengler, B.; Kirsch, D.: On the formation of initial ion velocities in matrix-assisted laser desorption ionization: Virtual desorption time as an additional parameter describing ion ejection dynamics. Int. J. Mass Spectrom. 226, 71-83 (2003)
17. Juhasz, P.; Vestal, M.L.; Martin, S.A.: On the initial velocity of ions generated by matrix-assisted laser desorption ionization and its effect on the calibration of delayed extraction time-of-flight mass spectra. J. Am. Soc. Mass Spectrom. 8, 209-217 (1997)
18. α-C bond cleavage of the peptide backbone in MALDI in-source decay using salicylic acid derivative matrices. J. Am. Soc. Mass Spectrom. 22, 1224-1233 (2011)
19. Asakawa, D.; Takayama, M.: Fragmentation processes of hydrogen-deficient peptide radicals in matrix-assisted laser desorption/ionization in-source decay mass spectrometry. J. Phys. Chem. B 116, 4016-4023 (2012)