Fragmentation of peptides in MALDI in-source decay mediated by hydrogen radicals

Analytical Chemistry

Volumn 77, Issue 1, 2005, Pages 172-177

  Köcher, Thomas ^a   Engström, Åke ^a   Zubarev, Roman A ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRON CAPTURE DISSOCIATION (ECD); FRAGMENTATION; HYDROGEN RADICALS; IN-SOURCE DECAY (ISD);

DECAY (ORGANIC); DESORPTION; DISSOCIATION; IONIZATION; MATRIX ALGEBRA;

HYDROGEN;

CARBON; HYDROGEN; HYDROGEN RADICAL; NITROGEN; PEPTIDE; PEPTIDE FRAGMENT; RADICAL; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; DEGRADATION; DEUTERIUM HYDROGEN EXCHANGE; DISSOCIATION; ELECTRON; ELECTRON CAPTURE DISSOCIATION; IN SOURCE DECAY; IONIZATION; MATRIX ASSISTED LASER DESORPTION IONIZATION; PEPTIDE FRAGMENTATION; PHOTOCHEMISTRY; PLUME; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTON TRANSPORT;

ELECTRONS; FREE RADICALS; HYDROGEN; PEPTIDES; PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 11844304974     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac0489115     Document Type: Article

References (38)

1. Fenn, J. B.; Mann, M.; Meng, C. K.; Wong, S. F.; Whitehouse, C. M. Science 1989, 246, 64-71.
2. Karas, M.; Hillenkamp, F. Anal. Chem. 1988, 60, 2299-2301.
3. Gavin, A. C.; Bosche, M.; Krause, R.; Grandi, P.; Marzioch, M.; Bauer, A.; Schulte, J.; Rick, J. M.; Michon, A. M.; Cruciat, C. M.; Remor, M.; Hofert, C.; Schelder, M.; Brajenovic, M.; Ruffner, H.; Merino, A.; Klein, K.; Hudak, M.; Dickson, D.; Rudi, T.; Gnau, V.; Bauch, A.; Bastuck, S.; Huhse, B.; Leutwein, C.; Heurtier, M. A.; Copley, R. R.; Edelmann, A.; Querfurth, E.; Rybin, V.; Drewes, G.; Raida, M.; Bouwmeester, T.; Bork, P.; Seraphin, B.; Kuster, B.; Neubauer, G.; Superti-Furga, G. Nature 2002, 415, 141-147.
4. Mootha, V. K.; Bunkenborg, J.; Olsen, J. V.; Hjerrild, M.; Wisniewski, J. R.; Stahl, E.; Bolouri, M. S.; Ray, H. N.; Sihag, S.; Kamal, M.; Patterson, N.; Lander, E. S.; Mann, M. Cell 2003, 115, 629-640.
5. Schirmer, E. C.; Florens, L.; Guan, T.; Yates, J. R., 3rd; Gerace, L. Science 2003, 301, 1380-1382.
6. Karas, M.; Bachmann, D.; Bahr, U.; Hillenkamp, F. Int. J. Mass Spectrom. Ion Processes 1987, 78, 53-68.
7. Brown, R. S.; Lennon, J. J. Anal. Chem. 1995, 67, 3990-3999.
8. Brown, R. S.; Feng, J.; Reiber, D. C. Int. J. Mass Spectrom. Ion Processes 1997, 169/170, 1-18.
9. Spengler, B.; Kirsch, D.; Kaufmann, R.; Jaeger, E. Rapid Commun. Mass Spectrom. 1992, 6, 105-108.
10. Reiber, D. C.; Grover, T. A.; Brown, R. S. Anal. Chem. 1998, 70, 673-683.
11. Suckau, D.; Resemann, A. Anal. Chem. 2003, 75, 5817-5824.
12. Reid, G. E.; McLuckey, S. A. J. Mass Spectrom. 2002, 37, 663-675.
13. Ge, Y.; Lawhorn, B. G.; El Naggar, M.; Strauss, E.; Park, J. H.; Begley, T. P.; McLafferty, F. W. J. Am. Chem. Soc. 2002, 124, 672-678.
14. Zubarev, R. A.; Kelleher, N. L.; McLafferty, F. W. J. Am. Chem. Soc. 1998, 120, 3265-3266.
15. Zubarev, R. A.; Horn, D. M.; Fridriksson, E. K.; Kelleher, N. L.; Kruger, N. A.; Lewis, M. A.; Carpenter, B. K.; McLafferty, F. W. Anal. Chem. 2000, 72, 563-573.
16. Horn, D. M.; Ge, Y.; McLafferty, F. W. Anal. Chem. 2000, 72, 4778-4784.
17. Katta, V.; Chow, D. T.; Rohde, M. F. Anal. Chem. 1998, 70, 4410-4416.
18. Chaurand P.; Luetzenkirchen F.; Spengler B. J. Am. Soc. Mass Spectrom. 1999, 10, 91-103.
19. Takayama, M. J. Am. Soc. Mass Spectrom. 2001, 12, 420-427.
20. Karas, M.; Kruger, R. Chem. Rev. 2003, 103, 427-440.
21. Karas, M.; Gluckmann, M.; Schafer, J. J. Mass Spectrom. 2000, 35, 1-12.
22. Knochenmuss, R.; Zenobi, R. Chem. Rev. 2003, 103, 441-452.
23. Zubarev, R. A.; Haselmann, K. F.; Budnik, B.; Kjeldsen, F.; Jensen F. Eur. J. Mass Spectrom. 2002, 8, 337-349.
24. Gorshkov, M. V.; Frankevich, V. E.; Zenobi, R. Eur. J. Mass Spectrom. 2002, 8, 67-69.
25. Frankevich, V.; Knochenmuss, R.; Zenobi, R. Int. J. Mass Specrom. 2002, 220, 11-19.
26. Knochenmuss, R. Anal. Chem. 2004, 76, 3179-3184.
27. Patterson, S. D.; Katta, V. Anal. Chem. 1994, 66, 3727-3732.
28. Lennon, J. J.; Walsh, K. A. Protein Sci. 1999, 8, 2487-2493.
29. Takayama, M.; Tsugita, A. Electrophoresis 2000, 21, 1670-1677.
30. Takayama, M. J. Am. Soc. Mass Spectrom. 2001, 12, 1044-1049.
31. Hunt, D. F.; Yates, J. R., 3rd; Shabanowitz, J.; Winston, S.; Hauer, C. R. Proc. Natl. Acad. Sci. U.S.A. 1986, 83, 6233-6237.
32. Roepstorff, P.; Fohlman, J. Biomed. Mass Spectrom. 1984, 11, 601.
33. Kjeldsen, F.; Haselmann, K. F.; Budnik, B. A.; Jensen, F.; Zubarev, R. A. Chem. Phys. Lett. 2002, 356, 201-206.
34. Mormann, M.; Macek, B.; de Peredo, A. G.; Hofsteenge, J.; Peter-Katalinic, J. Int. J. Mass Spectrom. 2004, 234, 11-21.
35. Kleinnijenhuis, A. J.; Duursma, M. C.; Breukink, E.; Heeren, R. M.; Heck, A. J. Anal. Chem. 2003, 75, 3219-3225.
36. Frankevich, V. E.; Zhang, J.; Friess, S. D.; Dashtiev, M.; Zenobi, R. Anal. Chem. 2003, 75, 6063-6067.
37. Frankevich, V.; Zhang, J.; Dashtiev, M.; Zenobi, R. Rapid Commun. Mass Spectrom. 2003, 17, 2343-2348.
38. Beavis, R. C.; Chaudhary, T.; Chait, B. T. Org. Mass Spectrom 1992, 27, 156-158.