-
1
-
-
78149471570
-
Autophagy in neurodegenerative disorders: Pathogenic roles and therapeutic implications
-
CrossRef Medline
-
Banerjee R, Beal MF, Thomas B (2010) Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications. Trends Neurosci 33:541-549. CrossRef Medline
-
(2010)
Trends Neurosci
, vol.33
, pp. 541-549
-
-
Banerjee, R.1
Beal, M.F.2
Thomas, B.3
-
2
-
-
0027433553
-
Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid
-
Medline
-
Beal MF, Brouillet E, Jenkins BG, Ferrante RJ, Kowall NW, Miller JM, Storey E, Srivastava R, Rosen BR, Hyman BT (1993) Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid. J Neurosci 13:4181-4192. Medline
-
(1993)
J Neurosci
, vol.13
, pp. 4181-4192
-
-
Beal, M.F.1
Brouillet, E.2
Jenkins, B.G.3
Ferrante, R.J.4
Kowall, N.W.5
Miller, J.M.6
Storey, E.7
Srivastava, R.8
Rosen, B.R.9
Hyman, B.T.10
-
3
-
-
0038113064
-
A dual role of adenosine A2A receptors in 3-nitropropionic acidinduced striatal lesions: Implications for the neuroprotective potential of A2A antagonists
-
Medline
-
Blum D, Galas MC, Pintor A, Brouillet E, Ledent C, Muller CE, Bantubungi K, Galluzzo M, Gall D, Cuvelier L, Rolland AS, Popoli P, Schiffmann SN (2003) A dual role of adenosine A2A receptors in 3-nitropropionic acidinduced striatal lesions: implications for the neuroprotective potential of A2A antagonists. J Neurosci 23:5361-5369. Medline
-
(2003)
J Neurosci
, vol.23
, pp. 5361-5369
-
-
Blum, D.1
Galas, M.C.2
Pintor, A.3
Brouillet, E.4
Ledent, C.5
Muller, C.E.6
Bantubungi, K.7
Galluzzo, M.8
Gall, D.9
Cuvelier, L.10
Rolland, A.S.11
Popoli, P.12
Schiffmann, S.N.13
-
4
-
-
0031914584
-
Partial inhibition of brain succinate dehydrogenase by 3-nitropropionic acid is sufficient to initiate striatal degeneration in rat
-
Medline
-
Brouillet E, Guyot MC, Mittoux V, Altairac S, Condé F, Palfi S, Hantraye P (1998) Partial inhibition of brain succinate dehydrogenase by 3-nitropropionic acid is sufficient to initiate striatal degeneration in rat. J Neurochem 70:794-805. Medline
-
(1998)
J Neurochem
, vol.70
, pp. 794-805
-
-
Brouillet, E.1
Guyot, M.C.2
Mittoux, V.3
Altairac, S.4
Condé, F.5
Palfi, S.6
Hantraye, P.7
-
5
-
-
29144468251
-
3-Nitropropionic acid: A mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease
-
CrossRef Medline
-
Brouillet E, Jacquard C, Bizat N, Blum D (2005) 3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease. J Neurochem 95: 1521-1540. CrossRef Medline
-
(2005)
J Neurochem
, vol.95
, pp. 1521-1540
-
-
Brouillet, E.1
Jacquard, C.2
Bizat, N.3
Blum, D.4
-
6
-
-
79551655290
-
Huntington's disease: Can mice lead the way to treatment?
-
CrossRef Medline
-
Crook ZR, Housman D (2011) Huntington's disease: can mice lead the way to treatment? Neuron 69:423-435. CrossRef Medline
-
(2011)
Neuron
, vol.69
, pp. 423-435
-
-
Crook, Z.R.1
Housman, D.2
-
7
-
-
80053573543
-
Small changes, big impact: Posttranslational modifications and function of huntingtin in Huntington disease
-
CrossRef Medline
-
Ehrnhoefer DE, Sutton L, Hayden MR (2011) Small changes, big impact: posttranslational modifications and function of huntingtin in Huntington disease. Neuroscientist 17:475-492. CrossRef Medline
-
(2011)
Neuroscientist
, vol.17
, pp. 475-492
-
-
Ehrnhoefer, D.E.1
Sutton, L.2
Hayden, M.R.3
-
8
-
-
38649098428
-
The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons
-
CrossRef Medline
-
Errico F, Santini E, Migliarini S, Borgkvist A, Centonze D, Nasti V, Carta M, De Chiara V, Prosperetti C, Spano D, Herve D, Pasqualetti M, Di Lauro R, Fisone G, Usiello A (2008) The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons. Mol Cell Neurosci 37:333-345. CrossRef Medline
-
(2008)
Mol Cell Neurosci
, vol.37
, pp. 333-345
-
-
Errico, F.1
Santini, E.2
Migliarini, S.3
Borgkvist, A.4
Centonze, D.5
Nasti, V.6
Carta, M.7
de Chiara, V.8
Prosperetti, C.9
Spano, D.10
Herve, D.11
Pasqualetti, M.12
Di Lauro, R.13
Fisone, G.14
Usiello, A.15
-
9
-
-
0033568070
-
Rhes: A striatal-specific Ras homolog related to Dexras1
-
CrossRef Medline
-
Falk JD, Vargiu P, Foye PE, Usui H, Perez J, Danielson PE, Lerner DL, Bernal J, Sutcliffe JG (1999) Rhes: A striatal-specific Ras homolog related to Dexras1. J Neurosci Res 57:782-788. CrossRef Medline
-
(1999)
J Neurosci Res
, vol.57
, pp. 782-788
-
-
Falk, J.D.1
Vargiu, P.2
Foye, P.E.3
Usui, H.4
Perez, J.5
Danielson, P.E.6
Lerner, D.L.7
Bernal, J.8
Sutcliffe, J.G.9
-
10
-
-
84857058225
-
Control of autophagy as a therapy for neurodegenerative disease
-
CrossRef Medline
-
Harris H, Rubinsztein DC (2012) Control of autophagy as a therapy for neurodegenerative disease. Nat Rev Neurol 8:108-117. CrossRef Medline
-
(2012)
Nat Rev Neurol
, vol.8
, pp. 108-117
-
-
Harris, H.1
Rubinsztein, D.C.2
-
12
-
-
84862663712
-
Sustained therapeutic reversal of Huntington's disease by transient repression of Huntingtin synthesis
-
CrossRef Medline
-
Kordasiewicz HB, Stanek LM, Wancewicz EV, Mazur C, McAlonis MM, Pytel KA, Artates JW, Weiss A, Cheng SH, Shihabuddin LS, Hung G, Bennett CF, Cleveland DW (2012) Sustained therapeutic reversal of Huntington's disease by transient repression of Huntingtin synthesis. Neuron 74:1031-1044. CrossRef Medline
-
(2012)
Neuron
, vol.74
, pp. 1031-1044
-
-
Kordasiewicz, H.B.1
Stanek, L.M.2
Wancewicz, E.V.3
Mazur, C.4
McAlonis, M.M.5
Pytel, K.A.6
Artates, J.W.7
Weiss, A.8
Cheng, S.H.9
Shihabuddin, L.S.10
Hung, G.11
Bennett, C.F.12
Cleveland, D.W.13
-
13
-
-
77951665859
-
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
-
CrossRef Medline
-
Martinez-Vicente M, Talloczy Z, Wong E, Tang G, Koga H, Kaushik S, de Vries R, Arias E, Harris S, Sulzer D, Cuervo AM (2010) Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease. Nat Neurosci 13:567-576. CrossRef Medline
-
(2010)
Nat Neurosci
, vol.13
, pp. 567-576
-
-
Martinez-Vicente, M.1
Talloczy, Z.2
Wong, E.3
Tang, G.4
Koga, H.5
Kaushik, S.6
de Vries, R.7
Arias, E.8
Harris, S.9
Sulzer, D.10
Cuervo, A.M.11
-
14
-
-
84874641856
-
Rhes is a striatal-enriched protein with pathophysiologic relevance
-
Mealer RG, Snyder SH (2012) Rhes is a striatal-enriched protein with pathophysiologic relevance. Eur J Neurodegen Dis 1:89-100.
-
(2012)
Eur J Neurodegen Dis
, vol.1
, pp. 89-100
-
-
Mealer, R.G.1
Snyder, S.H.2
-
15
-
-
84856200717
-
Exploration of sex differences in Rhes effects in dopamine mediated behaviors
-
CrossRef Medline
-
Quintero GC, Spano D (2011) Exploration of sex differences in Rhes effects in dopamine mediated behaviors. Neuropsychiatr Dis Treat 7:697-706. CrossRef Medline
-
(2011)
Neuropsychiatr Dis Treat
, vol.7
, pp. 697-706
-
-
Quintero, G.C.1
Spano, D.2
-
16
-
-
2642586352
-
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
-
CrossRef Medline
-
Ravikumar B, Vacher C, Berger Z, Davies JE, Luo S, Oroz LG, Scaravilli F, Easton DF, Duden R, O'Kane CJ, Rubinsztein DC (2004) Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. Nat Genet 36:585-595. CrossRef Medline
-
(2004)
Nat Genet
, vol.36
, pp. 585-595
-
-
Ravikumar, B.1
Vacher, C.2
Berger, Z.3
Davies, J.E.4
Luo, S.5
Oroz, L.G.6
Scaravilli, F.7
Easton, D.F.8
Duden, R.9
O'Kane, C.J.10
Rubinsztein, D.C.11
-
17
-
-
78650031174
-
Huntington's disease: From molecular pathogenesis to clinical treatment
-
CrossRef Medline
-
Ross CA, Tabrizi SJ (2011) Huntington's disease: from molecular pathogenesis to clinical treatment. Lancet Neurol 10:83-98. CrossRef Medline
-
(2011)
Lancet Neurol
, vol.10
, pp. 83-98
-
-
Ross, C.A.1
Tabrizi, S.J.2
-
18
-
-
79551530731
-
Oligonucleotide therapeutic approaches for Huntington disease
-
CrossRef Medline
-
Sah DW, Aronin N (2011) Oligonucleotide therapeutic approaches for Huntington disease. J Clin Invest 121:500-507. CrossRef Medline
-
(2011)
J Clin Invest
, vol.121
, pp. 500-507
-
-
Sah, D.W.1
Aronin, N.2
-
19
-
-
79960322940
-
Decreased striatal RGS2 expression is neuroprotective in Huntington's disease (HD) and exemplifies a compensatory aspect of HD-induced gene regulation
-
CrossRef Medline
-
Seredenina T, Gokce O, Luthi-Carter R (2011) Decreased striatal RGS2 expression is neuroprotective in Huntington's disease (HD) and exemplifies a compensatory aspect of HD-induced gene regulation. PLoS One 6:e22231. CrossRef Medline
-
(2011)
PLoS One
, vol.6
-
-
Seredenina, T.1
Gokce, O.2
Luthi-Carter, R.3
-
20
-
-
2942753949
-
Rhes is involved in striatal function
-
CrossRef Medline
-
Spano D, Branchi I, Rosica A, Pirro MT, Riccio A, Mithbaokar P, Affuso A, Arra C, Campolongo P, Terracciano D, Macchia V, Bernal J, Alleva E, Di Lauro R (2004) Rhes is involved in striatal function. Mol Cell Biol 24: 5788-5796. CrossRef Medline
-
(2004)
Mol Cell Biol
, vol.24
, pp. 5788-5796
-
-
Spano, D.1
Branchi, I.2
Rosica, A.3
Pirro, M.T.4
Riccio, A.5
Mithbaokar, P.6
Affuso, A.7
Arra, C.8
Campolongo, P.9
Terracciano, D.10
Macchia, V.11
Bernal, J.12
Alleva, E.13
Di Lauro, R.14
-
21
-
-
77956408419
-
Does Huntingtin play a role in selective macroautophagy?
-
CrossRef Medline
-
Steffan JS (2010) Does Huntingtin play a role in selective macroautophagy? Cell Cycle 9:3401-3413. CrossRef Medline
-
(2010)
Cell Cycle
, vol.9
, pp. 3401-3413
-
-
Steffan, J.S.1
-
22
-
-
11144353613
-
SUMO modification of Huntingtin and Huntington's disease pathology
-
CrossRef Medline
-
Steffan JS, Agrawal N, Pallos J, Rockabrand E, Trotman LC, Slepko N, Illes K, Lukacsovich T, Zhu YZ, Cattaneo E, Pandolfi PP, Thompson LM, Marsh JL (2004) SUMO modification of Huntingtin and Huntington's disease pathology. Science 304:100-104. CrossRef Medline
-
(2004)
Science
, vol.304
, pp. 100-104
-
-
Steffan, J.S.1
Agrawal, N.2
Pallos, J.3
Rockabrand, E.4
Trotman, L.C.5
Slepko, N.6
Illes, K.7
Lukacsovich, T.8
Zhu, Y.Z.9
Cattaneo, E.10
Pandolfi, P.P.11
Thompson, L.M.12
Marsh, J.L.13
-
23
-
-
66749167799
-
Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity
-
CrossRef Medline
-
Subramaniam S, Sixt KM, Barrow R, Snyder SH (2009) Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity. Science 324:1327-1330. CrossRef Medline
-
(2009)
Science
, vol.324
, pp. 1327-1330
-
-
Subramaniam, S.1
Sixt, K.M.2
Barrow, R.3
Snyder, S.H.4
-
24
-
-
84856281757
-
Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia
-
CrossRef Medline
-
Subramaniam S, Napolitano F, Mealer RG, Kim S, Errico F, Barrow R, Shahani N, Tyagi R, Snyder SH, Usiello A (2011) Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia. Nat Neurosci 15:191-193. CrossRef Medline
-
(2011)
Nat Neurosci
, vol.15
, pp. 191-193
-
-
Subramaniam, S.1
Napolitano, F.2
Mealer, R.G.3
Kim, S.4
Errico, F.5
Barrow, R.6
Shahani, N.7
Tyagi, R.8
Snyder, S.H.9
Usiello, A.10
-
25
-
-
78049231804
-
A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model
-
CrossRef Medline
-
Tsvetkov AS, Miller J, Arrasate M, Wong JS, Pleiss MA, Finkbeiner S (2010) A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model. Proc Natl Acad Sci U S A 107:16982-16987. CrossRef Medline
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 16982-16987
-
-
Tsvetkov, A.S.1
Miller, J.2
Arrasate, M.3
Wong, J.S.4
Pleiss, M.A.5
Finkbeiner, S.6
-
26
-
-
0842286707
-
The small GTP-binding protein, Rhes, regulates signal transduction from G protein-coupled receptors
-
CrossRef Medline
-
Vargiu P, De Abajo R, Garcia-Ranea JA, Valencia A, Santisteban P, Crespo P, Bernal J (2004) The small GTP-binding protein, Rhes, regulates signal transduction from G protein-coupled receptors. Oncogene 23: 559-568. CrossRef Medline
-
(2004)
Oncogene
, vol.23
, pp. 559-568
-
-
Vargiu, P.1
de Abajo, R.2
Garcia-Ranea, J.A.3
Valencia, A.4
Santisteban, P.5
Crespo, P.6
Bernal, J.7
-
27
-
-
77649219699
-
Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice
-
CrossRef Medline
-
Zheng S, Clabough EB, Sarkar S, Futter M, Rubinsztein DC, Zeitlin SO (2010) Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice. PLoS Genet 6:e1000838. CrossRef Medline
-
(2010)
PLoS Genet
, vol.6
-
-
Zheng, S.1
Clabough, E.B.2
Sarkar, S.3
Futter, M.4
Rubinsztein, D.C.5
Zeitlin, S.O.6
|