Double strand break repair components are frequent targets of microsatellite instability in endometrial cancer

European Journal of Cancer

Volumn 46, Issue 15, 2010, Pages 2821-2827

  Bilbao, Cristina ^a,b   Ramírez, Raquel ^a,b   Rodríguez, Germán ^a,b   Falcón, Orlando ^a,c   León, Laureano ^a,c   Díaz Chico, Nicolás ^a,b   Perucho, Manuel ^d,e   Díaz Chico, Juan Carlos ^a,b  

^a Madrid Spain   (Spain)

^b UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

^c HOSPITAL UNIVERSITARIO INSULAR DE GRAN CANARIA   (Spain)

^d Sandford Burnham Medical Research Institute   (United States)

^e Institute of Predictive and Personalized Medicine of Cancer IMPPC   (Spain)

Author keywords

Accumulative haploinsufficiency; Double strand break repair; Endometrial cancer; MCPH1; Microsatellite instability

Indexed keywords

ATR PROTEIN; BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; DOUBLE STRANDED DNA; GENOMIC DNA; MRE11 PROTEIN; RAD50 PROTEIN;

AGED; ARTICLE; ASSOCIATION; ATR GENE; BLOOD VESSEL; BRCA 1 GENE; CANCER GRADING; CANCER INVASION; CANCER STAGING; CLINICAL ARTICLE; CTIP GENE; DNA REPAIR; DNAPKCS GENE; DOUBLE STRANDED DNA BREAK; ENDOMETRIUM CANCER; FEMALE; FRAMESHIFT MUTATION; GENE; GENE DELETION; GENE INSERTION; HUMAN; HUMAN TISSUE; MICROCEPHALIN 1 GENE; MICROSATELLITE INSTABILITY; MRE 11 GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAD50 GENE; TUMOR SUPPRESSOR GENE;

AGED; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; ENDOMETRIAL NEOPLASMS; FEMALE; FRAMESHIFT MUTATION; GENES, NEOPLASM; HUMANS; MICROSATELLITE INSTABILITY;

EID: 77957197261     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2010.06.116     Document Type: Article

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