메뉴 건너뛰기




Volumn 38, Issue 3, 2003, Pages 130-140

Elevated Levels of Prostate-Specific Antigen (PSA) in Prostate Cancer Cells Expressing Mutant p53 is Associated with Tumor Metastasis

Author keywords

Prostate cancer progression and diagnosis; PSA; Tumor markers; Tumor suppressor genes

Indexed keywords

CISPLATIN; PROSTATE SPECIFIC ANTIGEN; PROTEIN P53; TUMOR MARKER;

EID: 0242490099     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/mc.10154     Document Type: Article
Times cited : (13)

References (44)
  • 1
    • 0033843891 scopus 로고    scopus 로고
    • Evaluation of prostatic specific antigen and digital rectal examination as screening tests for prostate cancer
    • Candas B, Cusan L, Gomez JL, et al. Evaluation of prostatic specific antigen and digital rectal examination as screening tests for prostate cancer. Prostate 2000;45:19-35.
    • (2000) Prostate , vol.45 , pp. 19-35
    • Candas, B.1    Cusan, L.2    Gomez, J.L.3
  • 4
    • 0030974734 scopus 로고    scopus 로고
    • The anti-androgen withdrawal syndrome
    • Wirth MP, Froschermaier SE. The anti-androgen withdrawal syndrome. Urol Res 1997;25(Suppl 2):S67-S71.
    • (1997) Urol Res , vol.25 , Issue.SUPPL. 2
    • Wirth, M.P.1    Froschermaier, S.E.2
  • 5
    • 0033583317 scopus 로고    scopus 로고
    • Androgen-independent induction of prostate specific antigen gene expression via cross-talk between androgen receptor and protein kinase A signal transduction pathways
    • Sadar MD. Androgen-independent induction of prostate specific antigen gene expression via cross-talk between androgen receptor and protein kinase A signal transduction pathways. J Biol Chem 1999;274:7777-7783.
    • (1999) J Biol Chem , vol.274 , pp. 7777-7783
    • Sadar, M.D.1
  • 6
    • 0033385487 scopus 로고    scopus 로고
    • Prostate cancer: Molecular biology of early progression to androgen independence
    • Sadar MD, Hussain M, Bruchovsky N. Prostate cancer: Molecular biology of early progression to androgen independence. Endocr Relat Cancer 1999;6:487-502.
    • (1999) Endocr Relat Cancer , vol.6 , pp. 487-502
    • Sadar, M.D.1    Hussain, M.2    Bruchovsky, N.3
  • 7
    • 0034731463 scopus 로고    scopus 로고
    • Regions of prostate-specific antigen (PSA) promoter confer androgen-independent expression of PSA in prostate cancer cells
    • Yeung F, Li X, Ellett J, Trapman J, Kao C, Chung LW. Regions of prostate-specific antigen (PSA) promoter confer androgen-independent expression of PSA in prostate cancer cells. J Biol Chem 2000;275:40846-40855.
    • (2000) J Biol Chem , vol.275 , pp. 40846-40855
    • Yeung, F.1    Li, X.2    Ellett, J.3    Trapman, J.4    Kao, C.5    Chung, L.W.6
  • 8
    • 0030481099 scopus 로고    scopus 로고
    • The role of the p53 tumor suppressor gene in prostate cancer: A possible biomarker?
    • Heidenberg HB, Bauer JJ, McLeod DG, Moul JW, Srivastava S. The role of the p53 tumor suppressor gene in prostate cancer: A possible biomarker? Urology 1996;48:971-979.
    • (1996) Urology , vol.48 , pp. 971-979
    • Heidenberg, H.B.1    Bauer, J.J.2    McLeod, D.G.3    Moul, J.W.4    Srivastava, S.5
  • 9
    • 0035043332 scopus 로고    scopus 로고
    • Mutations within the tumor suppressor gene p53 are not confined to a late event in prostate cancer progression - A review of the evidence
    • Downing SR, Jackson P, Russell PJ. Mutations within the tumor suppressor gene p53 are not confined to a late event in prostate cancer progression - a review of the evidence. Urol Oncol 2001;6:103-110.
    • (2001) Urol Oncol , vol.6 , pp. 103-110
    • Downing, S.R.1    Jackson, P.2    Russell, P.J.3
  • 10
    • 0028837632 scopus 로고
    • p53 nuclear protein expression is an independent prognostic marker in clinically localised prostate cancer patients undergoing radical prostatectomy
    • Bauer JJ, Sesterhenn IA, Mostofi KF, McLeod DG, Srivastava S, Moul JW. p53 nuclear protein expression is an independent prognostic marker in clinically localised prostate cancer patients undergoing radical prostatectomy. Clin Cancer Res 1995;1:1295-1300.
    • (1995) Clin Cancer Res , vol.1 , pp. 1295-1300
    • Bauer, J.J.1    Sesterhenn, I.A.2    Mostofi, K.F.3    McLeod, D.G.4    Srivastava, S.5    Moul, J.W.6
  • 11
    • 0029818270 scopus 로고    scopus 로고
    • Molecular therapy with recombinant p53 adenovirus in an androgen-independent, metastatic human prostate cancer model
    • Ko S, Gotoh A, Thalmann GN, et al. Molecular therapy with recombinant p53 adenovirus in an androgen-independent, metastatic human prostate cancer model. Hum Gene Ther 1996;7:1683-1691.
    • (1996) Hum Gene Ther , vol.7 , pp. 1683-1691
    • Ko, S.1    Gotoh, A.2    Thalmann, G.N.3
  • 12
    • 0037011989 scopus 로고    scopus 로고
    • Expression of prostate specific antigen is negatively regulated by p53
    • Gurova KV, Roklin OW, Krivokrysenko VI, et al. Expression of prostate specific antigen is negatively regulated by p53. Oncogene 2002;21:153-157.
    • (2002) Oncogene , vol.21 , pp. 153-157
    • Gurova, K.V.1    Roklin, O.W.2    Krivokrysenko, V.I.3
  • 13
    • 0035914313 scopus 로고    scopus 로고
    • p53 represses androgen-induced transactivation of prostate-specific antigen by disrupting hAR amino- to carboxyl-terminal interaction
    • Shenk JL, Fisher CJ, Chen S, Zhou X, Tillman K, Shemshedini L. p53 represses androgen-induced transactivation of prostate-specific antigen by disrupting hAR amino- to carboxyl-terminal interaction. J Biol Chem 2001;276:38472-38479.
    • (2001) J Biol Chem , vol.276 , pp. 38472-38479
    • Shenk, J.L.1    Fisher, C.J.2    Chen, S.3    Zhou, X.4    Tillman, K.5    Shemshedini, L.6
  • 14
    • 0024357799 scopus 로고
    • A simple method for the site-directed mutagenesis using the polymerase chain reaction
    • Hemsley AA. A simple method for the site-directed mutagenesis using the polymerase chain reaction. Nucl Acids Res 1989;17:6545-6551.
    • (1989) Nucl Acids Res , vol.17 , pp. 6545-6551
    • Hemsley, A.A.1
  • 15
    • 0029888978 scopus 로고    scopus 로고
    • Suramin-induced decrease in prostate-specific antigen expression with no effect on tumor growth in the LNCaP model of human prostate cancer
    • Thalmann GN, Sikes RA, Chang SM, Johnston DA, von Eschenbach AC, Chung LWK. Suramin-induced decrease in prostate-specific antigen expression with no effect on tumor growth in the LNCaP model of human prostate cancer. J Natl Cancer Inst 1996;88:794-801.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 794-801
    • Thalmann, G.N.1    Sikes, R.A.2    Chang, S.M.3    Johnston, D.A.4    Von Eschenbach, A.C.5    Chung, L.W.K.6
  • 16
    • 0032479367 scopus 로고    scopus 로고
    • Individual promoter and intron p53-binding motifs from the rat Cyclin G1 promoter region support transcriptional activation by p53, but do not show co-operative activation
    • Yardley G, Zauberman A, Oren M, Jackson P. Individual promoter and intron p53-binding motifs from the rat Cyclin G1 promoter region support transcriptional activation by p53, but do not show co-operative activation. FEBS Lett 1998;430:171-175.
    • (1998) FEBS Lett , vol.430 , pp. 171-175
    • Yardley, G.1    Zauberman, A.2    Oren, M.3    Jackson, P.4
  • 17
    • 0034285094 scopus 로고    scopus 로고
    • Methylation of a CpG island within the promoter region of the KAI1 metastasis suppressor gene is not responsible for down-regulation of KAI1 expression in invasive cancers or cancer cell lines
    • Jackson P, Millar D, Kingsley E, et al. Methylation of a CpG island within the promoter region of the KAI1 metastasis suppressor gene is not responsible for down-regulation of KAI1 expression in invasive cancers or cancer cell lines. Cancer Lett 1998;157:169-176.
    • (1998) Cancer Lett , vol.157 , pp. 169-176
    • Jackson, P.1    Millar, D.2    Kingsley, E.3
  • 18
    • 0028047976 scopus 로고
    • A microtiter plate assay for the characterisation of serine proteases by their esterase activity
    • Whittaker RG, Manthey MK, Le Broque DD, Hayes PJ. A microtiter plate assay for the characterisation of serine proteases by their esterase activity. Anal Biochem 1994;220:238-243.
    • (1994) Anal Biochem , vol.220 , pp. 238-243
    • Whittaker, R.G.1    Manthey, M.K.2    Le Broque, D.D.3    Hayes, P.J.4
  • 19
    • 0036080550 scopus 로고    scopus 로고
    • Gene therapy for prostate cancer delivered by ovine adenovirus and mediated by purine nucleoside phosphorylase and fludarabine in mouse models
    • Voeks D, Martiniello-Wilks R, Madden V, et al. Gene therapy for prostate cancer delivered by ovine adenovirus and mediated by purine nucleoside phosphorylase and fludarabine in mouse models. Gene Ther 2002;9:759-768.
    • (2002) Gene Ther , vol.9 , pp. 759-768
    • Voeks, D.1    Martiniello-Wilks, R.2    Madden, V.3
  • 20
    • 0022619991 scopus 로고
    • Bladder cancer xenografts: A model of tumor cell heterogeneity
    • Russell PJ, Raghavan D, Gregory P, et al. Bladder cancer xenografts: A model of tumor cell heterogeneity. Cancer Res 1986;46:2035-2040.
    • (1986) Cancer Res , vol.46 , pp. 2035-2040
    • Russell, P.J.1    Raghavan, D.2    Gregory, P.3
  • 21
    • 0033597213 scopus 로고    scopus 로고
    • p53 down-regulates human matrix metalloproteinase-1 (collagenase-1) gene expression
    • Sun YB, Sun Y, Wenger L, Rutter JL, Brinckerhoff CE, Cheung HS. p53 down-regulates human matrix metalloproteinase-1 (collagenase-1) gene expression. J Biol Chem 1999;274:11535-11540.
    • (1999) J Biol Chem , vol.274 , pp. 11535-11540
    • Sun, Y.B.1    Sun, Y.2    Wenger, L.3    Rutter, J.L.4    Brinckerhoff, C.E.5    Cheung, H.S.6
  • 22
    • 0032530579 scopus 로고    scopus 로고
    • The expression of the KAI1 gene, a metastasis suppressor, is directly activated by p53
    • Mashimo T, Watabe M, Hirota S, et al. The expression of the KAI1 gene, a metastasis suppressor, is directly activated by p53. Proc Natl Acad Sci USA 1998;95:11307-11311.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11307-11311
    • Mashimo, T.1    Watabe, M.2    Hirota, S.3
  • 23
    • 0027413629 scopus 로고
    • Growth of an androgen-sensitive human prostate cancer cell line, LNCaP, in nude mice
    • Lim DJ, Liu X, Sutkowski DM, Braun EJ, Lee C, Kozlowski JM. Growth of an androgen-sensitive human prostate cancer cell line, LNCaP, in nude mice. Prostate 1993;22:109-118.
    • (1993) Prostate , vol.22 , pp. 109-118
    • Lim, D.J.1    Liu, X.2    Sutkowski, D.M.3    Braun, E.J.4    Lee, C.5    Kozlowski, J.M.6
  • 24
    • 0035920197 scopus 로고    scopus 로고
    • Transcriptional repression by p53 through direct binding to a novel DNA element
    • Johnson RA, Ince TA, Scotto KW. Transcriptional repression by p53 through direct binding to a novel DNA element. J Biol Chem 2001;276:27716-27720.
    • (2001) J Biol Chem , vol.276 , pp. 27716-27720
    • Johnson, R.A.1    Ince, T.A.2    Scotto, K.W.3
  • 25
    • 0032853774 scopus 로고    scopus 로고
    • Mutant p53: Gain-of-function oncoproteins and wild-type p53 inactivators
    • Roemer K. Mutant p53: Gain-of-function oncoproteins and wild-type p53 inactivators. Biol Che Hoppe-Seyler 1999;380:879-887.
    • (1999) Biol Che Hoppe-Seyler , vol.380 , pp. 879-887
    • Roemer, K.1
  • 26
    • 0029824890 scopus 로고    scopus 로고
    • Transcriptional activation of the human epidermal growth factor receptor promoter by human p53
    • Ludes-Meyers JH, Subler MA, Shivakumar CV, et al. Transcriptional activation of the human epidermal growth factor receptor promoter by human p53. Mol Cell Biol 1996;16:6009-6019.
    • (1996) Mol Cell Biol , vol.16 , pp. 6009-6019
    • Ludes-Meyers, J.H.1    Subler, M.A.2    Shivakumar, C.V.3
  • 27
    • 0037063173 scopus 로고    scopus 로고
    • Novel gain of function activity of p53 mutants: Activation of the dUTPase gene expression leading to resistance to 5-fluorouracil
    • Pugacheva EN, Ivanov AV, Kravchenko JE, Kopnin BP, Levine AJ, Chumakov PM. Novel gain of function activity of p53 mutants: Activation of the dUTPase gene expression leading to resistance to 5-fluorouracil. Oncogene 2002;21:4595-4600.
    • (2002) Oncogene , vol.21 , pp. 4595-4600
    • Pugacheva, E.N.1    Ivanov, A.V.2    Kravchenko, J.E.3    Kopnin, B.P.4    Levine, A.J.5    Chumakov, P.M.6
  • 28
    • 0036569942 scopus 로고    scopus 로고
    • Expression of mitotic spindle checkpoint protein hsMAD1 correlates with cellular proliferation and is activated by gain-of-function p53 mutant
    • Iwanaga Y, Jiang KT. Expression of mitotic spindle checkpoint protein hsMAD1 correlates with cellular proliferation and is activated by gain-of-function p53 mutant. Cancer Res 2002;62:2618-2624.
    • (2002) Cancer Res , vol.62 , pp. 2618-2624
    • Iwanaga, Y.1    Jiang, K.T.2
  • 29
    • 0032543718 scopus 로고    scopus 로고
    • 'Gain of function' phenotype of tumor-derived mutant p53 requires the oligomerization/non-sequence-specific nucleic acid-binding domain
    • Lanyi A, Deb D, Seymour RC, Ludes-Meyers JH, Subler MA, Deb S. 'Gain of function' phenotype of tumor-derived mutant p53 requires the oligomerization/non-sequence-specific nucleic acid-binding domain. Oncogene 1998;16:3169-3176.
    • (1998) Oncogene , vol.16 , pp. 3169-3176
    • Lanyi, A.1    Deb, D.2    Seymour, R.C.3    Ludes-Meyers, J.H.4    Subler, M.A.5    Deb, S.6
  • 30
    • 0025887476 scopus 로고
    • Wild-type p53 can down-modulate the activity of various promoters
    • Ginsberg D, Mechta F, Yaniv M, Oren M. Wild-type p53 can down-modulate the activity of various promoters. Proc Natl Acad Sci USA 1991;88:9979-9983.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 9979-9983
    • Ginsberg, D.1    Mechta, F.2    Yaniv, M.3    Oren, M.4
  • 31
    • 0030852711 scopus 로고    scopus 로고
    • Androgen receptor-associated protein complex binds upstream of the androgen-responsive elements in the promoters of human prostate-specific antigen and kallikrein 2 genes
    • Sun Z, Pan J, Balk SP. Androgen receptor-associated protein complex binds upstream of the androgen-responsive elements in the promoters of human prostate-specific antigen and kallikrein 2 genes. Nucl Acids Res 1997;25:3318-3325.
    • (1997) Nucl Acids Res , vol.25 , pp. 3318-3325
    • Sun, Z.1    Pan, J.2    Balk, S.P.3
  • 33
    • 0032935293 scopus 로고    scopus 로고
    • Amplification of the androgen receptor gene is associated with p53 mutation in hormone-refractory recurrent prostate cancer
    • Koivisto PA, Rantala I. Amplification of the androgen receptor gene is associated with p53 mutation in hormone-refractory recurrent prostate cancer. J Pathol 1999;187:237-241.
    • (1999) J Pathol , vol.187 , pp. 237-241
    • Koivisto, P.A.1    Rantala, I.2
  • 34
    • 0029966627 scopus 로고    scopus 로고
    • Clustered p53 immunostaining-a novel pattern associated with prostate cancer progression
    • Yang G, Stapleton AMF, Wheeler TM, et al. Clustered p53 immunostaining-a novel pattern associated with prostate cancer progression. Clin Cancer Res 1996;2:399-401.
    • (1996) Clin Cancer Res , vol.2 , pp. 399-401
    • Yang, G.1    Stapleton, A.M.F.2    Wheeler, T.M.3
  • 35
    • 17044460982 scopus 로고    scopus 로고
    • Prognostic significance of p53 nuclear accumulation in localised prostate cancer treated with radical prostatectomy
    • Quinn DI, Henshall SM, Head DR, et al. Prognostic significance of p53 nuclear accumulation in localised prostate cancer treated with radical prostatectomy. Cancer Res 2000;60:1585-1594.
    • (2000) Cancer Res , vol.60 , pp. 1585-1594
    • Quinn, D.I.1    Henshall, S.M.2    Head, D.R.3
  • 36
    • 0030754058 scopus 로고    scopus 로고
    • Primary human prostate cancer cells harboring p53 mutations are clonally expanded in metastases
    • Stapleton AMF, Timme TL, Gousse AE, et al. Primary human prostate cancer cells harboring p53 mutations are clonally expanded in metastases. Clin Cancer Res 1997;3:1389-1397.
    • (1997) Clin Cancer Res , vol.3 , pp. 1389-1397
    • Stapleton, A.M.F.1    Timme, T.L.2    Gousse, A.E.3
  • 38
    • 0027331484 scopus 로고
    • p53 protein accumulation and gene mutation in the progression of human prostate carcinoma
    • Navone NM, Troncoso P, Pisters LL, et al. p53 protein accumulation and gene mutation in the progression of human prostate carcinoma. J Natl Cancer Inst 1993;85:1657-1669.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1657-1669
    • Navone, N.M.1    Troncoso, P.2    Pisters, L.L.3
  • 39
    • 0028060380 scopus 로고
    • Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
    • Dameron KM, Volpert OV, Tainsky MA, Bouck N. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 1994;265:1582-1584.
    • (1994) Science , vol.265 , pp. 1582-1584
    • Dameron, K.M.1    Volpert, O.V.2    Tainsky, M.A.3    Bouck, N.4
  • 40
    • 18744423089 scopus 로고    scopus 로고
    • Thrombospondin-1 expression in bladder cancer-association with p53 alterations, tumor angiogenesis, and tumor progression
    • Grossveld GD, Ginsberg DA, Stein JP, et al. Thrombospondin-1 expression in bladder cancer-association with p53 alterations, tumor angiogenesis, and tumor progression. J Natl Cancer Inst 1997;89:219-227.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 219-227
    • Grossveld, G.D.1    Ginsberg, D.A.2    Stein, J.P.3
  • 41
    • 0032101647 scopus 로고    scopus 로고
    • Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancer
    • Bouvet M, Ellis LM, Nishizaki M, et al. Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancer. Cancer Res 1996;58:2288-2292.
    • (1996) Cancer Res , vol.58 , pp. 2288-2292
    • Bouvet, M.1    Ellis, L.M.2    Nishizaki, M.3
  • 42
    • 0027958348 scopus 로고
    • Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression
    • Kieser A, Weich HA, Brandner G, Marme D, Kolch W. Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression. Oncogene 1994;9:963-969.
    • (1994) Oncogene , vol.9 , pp. 963-969
    • Kieser, A.1    Weich, H.A.2    Brandner, G.3    Marme, D.4    Kolch, W.5
  • 43
    • 0034096190 scopus 로고    scopus 로고
    • p53 regulates expression of the tumor suppressor gene maspin
    • Zou Z, Gao C, Nagaich AK, et al. p53 regulates expression of the tumor suppressor gene maspin. J Biol Chem 2000;275:6051-6054.
    • (2000) J Biol Chem , vol.275 , pp. 6051-6054
    • Zou, Z.1    Gao, C.2    Nagaich, A.K.3
  • 44
    • 0034646643 scopus 로고    scopus 로고
    • Wild type and mutant p53 differentially regulate the gene expression of human collagenase-3 (hMMP-13)
    • Sun Y, Cheung JM, Martel-Pelletier J, et al. Wild type and mutant p53 differentially regulate the gene expression of human collagenase-3 (hMMP-13). J Biol Chem 2000;275:11327-11332.
    • (2000) J Biol Chem , vol.275 , pp. 11327-11332
    • Sun, Y.1    Cheung, J.M.2    Martel-Pelletier, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.