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Volumn 31, Issue 19, 2003, Pages 5469-5482

RNA structure of trinucleotide repeats associated with human neurological diseases

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CYTOSINE; GUANINE; RNA; MESSENGER RNA;

EID: 0142009656     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg766     Document Type: Article
Times cited : (185)

References (54)
  • 1
    • 0033858199 scopus 로고    scopus 로고
    • Microsatellites in different eukaryotic genomes: Survey and analysis
    • Toth,G., Gaspari,Z. and Jurka,J. (2000) Microsatellites in different eukaryotic genomes: survey and analysis. Genome Res., 10, 967-981.
    • (2000) Genome Res. , vol.10 , pp. 967-981
    • Toth, G.1    Gaspari, Z.2    Jurka, J.3
  • 2
    • 0036072745 scopus 로고    scopus 로고
    • Tandem repeats in protein coding regions of primate genes
    • Borstnik,B. and Pumpernik,D. (2002) Tandem repeats in protein coding regions of primate genes. Genome Res., 12, 909-915.
    • (2002) Genome Res. , vol.12 , pp. 909-915
    • Borstnik, B.1    Pumpernik, D.2
  • 3
    • 0031081111 scopus 로고    scopus 로고
    • Simple sequence repeats as a source of quantitative genetic variation
    • Kashi,Y., King,D. and Soller,M. (1997) Simple sequence repeats as a source of quantitative genetic variation. Trends Genet., 13, 74-78.
    • (1997) Trends Genet. , vol.13 , pp. 74-78
    • Kashi, Y.1    King, D.2    Soller, M.3
  • 6
    • 0029762012 scopus 로고    scopus 로고
    • CAG trinucleotide RNA repeats interact with RNA-binding proteins
    • McLaughlin,B.A., Spencer,C. and Eberwine,J. (1996) CAG trinucleotide RNA repeats interact with RNA-binding proteins. Am. J. Hum. Genet., 59, 561-569.
    • (1996) Am. J. Hum. Genet. , vol.59 , pp. 561-569
    • McLaughlin, B.A.1    Spencer, C.2    Eberwine, J.3
  • 7
    • 0030043709 scopus 로고    scopus 로고
    • Novel proteins with binding specificity for DNA CTG repeats and RNA CUG repeats: Implications for myotonic dystrophy
    • Timchenko,L.T., Timchenko,N.A., Caskey,C.T. and Roberts,R. (1996) Novel proteins with binding specificity for DNA CTG repeats and RNA CUG repeats: implications for myotonic dystrophy. Hum. Mol. Genet., 5, 115-121.
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 115-121
    • Timchenko, L.T.1    Timchenko, N.A.2    Caskey, C.T.3    Roberts, R.4
  • 8
    • 0033198739 scopus 로고    scopus 로고
    • Visualization of double-stranded RNAs from the myotonic dystrophy protein kinase gene and interactions with CUG-binding protein
    • Michalowski,S., Miller,J.W., Urbinati,C.R., Paliouras,M., Swanson,M.S. and Griffith,J. (1999) Visualization of double-stranded RNAs from the myotonic dystrophy protein kinase gene and interactions with CUG-binding protein. Nucleic Acids Res., 27, 3534-3542.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 3534-3542
    • Michalowski, S.1    Miller, J.W.2    Urbinati, C.R.3    Paliouras, M.4    Swanson, M.S.5    Griffith, J.6
  • 9
    • 0033983537 scopus 로고    scopus 로고
    • Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR
    • Tian,B., White,R.J., Xia,T., Welle,S., Turner,D.H., Mathews,M.B. and Thornton,C.A. (2000) Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR. RNA, 6, 79-87.
    • (2000) RNA , vol.6 , pp. 79-87
    • Tian, B.1    White, R.J.2    Xia, T.3    Welle, S.4    Turner, D.H.5    Mathews, M.B.6    Thornton, C.A.7
  • 10
    • 0035878553 scopus 로고    scopus 로고
    • Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue
    • Peel,L., Rao,R.V., Cottrell,B.A., Hayden,M.R., Ellerby,L.M. and Bredesen,D.E. (2001) Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue. Hum. Mol. Genet., 10, 1531-1538.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1531-1538
    • Peel, L.1    Rao, R.V.2    Cottrell, B.A.3    Hayden, M.R.4    Ellerby, L.M.5    Bredesen, D.E.6
  • 11
    • 0033073594 scopus 로고    scopus 로고
    • Myotonic dystrophy: The role of RNA CUG triplet repeats
    • Timchenko,L.T. (1999) Myotonic dystrophy: the role of RNA CUG triplet repeats. Am. J. Hum. Genet., 64, 360-364.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 360-364
    • Timchenko, L.T.1
  • 12
    • 0036347525 scopus 로고    scopus 로고
    • Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy
    • Mankodi,A., Takahashi,M.P., Jiang,H., Beck,C.L., Bowers,W.J., Moxley,R.T., Cannon,S.C. and Thoruton,C.A. (2002) Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy. Mol. Cell, 10, 35-44.
    • (2002) Mol. Cell , vol.10 , pp. 35-44
    • Mankodi, A.1    Takahashi, M.P.2    Jiang, H.3    Beck, C.L.4    Bowers, W.J.5    Moxley, R.T.6    Cannon, S.C.7    Thoruton, C.A.8
  • 13
    • 0032906538 scopus 로고    scopus 로고
    • Cardiac elav-type RNA-binding protein (ETR-3) binds to RNA CUG repeats expanded in myotonic dystrophy
    • Lu,X., Timchenko,N.A. and Timchenko,L.T. (1999) Cardiac elav-type RNA-binding protein (ETR-3) binds to RNA CUG repeats expanded in myotonic dystrophy. Hum. Mol. Genet., 8, 53-60.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 53-60
    • Lu, X.1    Timchenko, N.A.2    Timchenko, L.T.3
  • 14
    • 0032076126 scopus 로고    scopus 로고
    • Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy
    • Philips,A.V., Timchenko,L.T. and Cooper,T.A. (1998) Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy. Science, 280, 737-741.
    • (1998) Science , vol.280 , pp. 737-741
    • Philips, A.V.1    Timchenko, L.T.2    Cooper, T.A.3
  • 15
    • 0035800470 scopus 로고    scopus 로고
    • Biomedicine. Reconstructing myotonic dystrophy
    • Tapscott,S.J. and Thornton,C.A. (2001) Biomedicine. Reconstructing myotonic dystrophy. Science, 293, 816-817.
    • (2001) Science , vol.293 , pp. 816-817
    • Tapscott, S.J.1    Thornton, C.A.2
  • 16
    • 0036347927 scopus 로고    scopus 로고
    • Loss of the muscle-specific chloride channel in type 1 myotonic dystrophy due to misregulated alternative splicing
    • Charlet,B.N., Savkur,R.S., Singh,G., Philips,A.V., Grice,E.A. and Cooper,T.A. (2002) Loss of the muscle-specific chloride channel in type 1 myotonic dystrophy due to misregulated alternative splicing. Mol. Cell, 10, 45-53.
    • (2002) Mol. Cell , vol.10 , pp. 45-53
    • Charlet, B.N.1    Savkur, R.S.2    Singh, G.3    Philips, A.V.4    Grice, E.A.5    Cooper, T.A.6
  • 17
    • 0035445656 scopus 로고    scopus 로고
    • The myotonic dystrophy expanded CUG repeat tract is necessary but not sufficient to disrupt C2C12 myoblast differentiation
    • Amack,J.D. and Mahadevan,M.S. (2001) The myotonic dystrophy expanded CUG repeat tract is necessary but not sufficient to disrupt C2C12 myoblast differentiation. Hum. Mol. Genet., 10, 1879-1887.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1879-1887
    • Amack, J.D.1    Mahadevan, M.S.2
  • 18
    • 0037064571 scopus 로고    scopus 로고
    • Mutant DMPK 3′-UTR transcripts disrupt C2C12 myogenic differentiation by compromising MyoD
    • Amack,J.D., Reagan,S.R. and Mahadevan,M.S. (2002) Mutant DMPK 3′-UTR transcripts disrupt C2C12 myogenic differentiation by compromising MyoD. J. Cell Biol., 159, 419-429.
    • (2002) J. Cell Biol. , vol.159 , pp. 419-429
    • Amack, J.D.1    Reagan, S.R.2    Mahadevan, M.S.3
  • 19
    • 0034873099 scopus 로고    scopus 로고
    • Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy
    • Savkur,R.S., Philips,A.V. and Cooper,T.A. (2001) Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy. Nature Genet., 29, 40-47.
    • (2001) Nature Genet. , vol.29 , pp. 40-47
    • Savkur, R.S.1    Philips, A.V.2    Cooper, T.A.3
  • 20
    • 0033570899 scopus 로고    scopus 로고
    • CUG repeat binding protein (CUGBP1) interacts with the 5′ region of C/EBPbeta mRNA and regulates translation of C/EBPbeta isoforms
    • Timchenko,N.A., Welm,A.L., Lu,X. and Timchenko,L.T. (1999B) CUG repeat binding protein (CUGBP1) interacts with the 5′ region of C/EBPbeta mRNA and regulates translation of C/EBPbeta isoforms. Nucleic Acids Res., 27, 4517-4525.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 4517-4525
    • Timchenko, N.A.1    Welm, A.L.2    Lu, X.3    Timchenko, L.T.4
  • 24
    • 0036591663 scopus 로고    scopus 로고
    • Dominantly inherited, non-coding microsatellite expansion disorders
    • Ranum,L.P. and Day,J.W. (2002) Dominantly inherited, non-coding microsatellite expansion disorders. Curr. Opin. Genet. Dev., 12, 266-271.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 266-271
    • Ranum, L.P.1    Day, J.W.2
  • 25
    • 0030664357 scopus 로고    scopus 로고
    • Dynamic mutation: Possible mechanisms and significance in human disease
    • Richards,R.I. and Sutherland,G.R. (1997) Dynamic mutation: possible mechanisms and significance in human disease. Trends Biochem. Sci., 22, 432-436.
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 432-436
    • Richards, R.I.1    Sutherland, G.R.2
  • 26
    • 0034640011 scopus 로고    scopus 로고
    • Fourteen and counting: Unraveling trinucleotide repeat diseases
    • Cummings,C.J. and Zoghbi,H.Y. (2000) Fourteen and counting: unraveling trinucleotide repeat diseases. Hum. Mol. Genet., 9, 909-916.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 909-916
    • Cummings, C.J.1    Zoghbi, H.Y.2
  • 27
    • 0035201633 scopus 로고    scopus 로고
    • The intrinsically unstable life of DNA triplet repeats associated with human hereditary disorders
    • Bowater,R.P. and Wells,R.D. (2001) The intrinsically unstable life of DNA triplet repeats associated with human hereditary disorders. Prog. Nucleic Acid Res. Mol. Biol., 66, 159-202.
    • (2001) Prog. Nucleic Acid Res. Mol. Biol. , vol.66 , pp. 159-202
    • Bowater, R.P.1    Wells, R.D.2
  • 28
    • 0035859024 scopus 로고    scopus 로고
    • Neurodegenerative diseases. Origins of instability
    • Sinden,R.R. (2001) Neurodegenerative diseases. Origins of instability. Nature, 411, 757-758.
    • (2001) Nature , vol.411 , pp. 757-758
    • Sinden, R.R.1
  • 29
    • 1842406027 scopus 로고    scopus 로고
    • CUG repeats present in myotonin kinase RNA form metastable 'slippery' hairpins
    • Napierala,M. and Krzyzosiak,W.J. (1997) CUG repeats present in myotonin kinase RNA form metastable 'slippery' hairpins. J. Biol. Chem., 272, 31079-31085.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31079-31085
    • Napierala, M.1    Krzyzosiak, W.J.2
  • 31
    • 0010216317 scopus 로고    scopus 로고
    • RNA structure modules with trinucleotide repeat motifs
    • Barciszewski,J. and Clark,B.F.C. (eds), Kluwer, Dordrecht, The Netherlands
    • Krzyzosiak,W.J., Napierala,M. and Drozdz,M. (1999) RNA structure modules with trinucleotide repeat motifs. In Barciszewski,J. and Clark,B.F.C. (eds), RNA Biochemistry and Biotechnology. Kluwer, Dordrecht, The Netherlands, pp. 303-314.
    • (1999) RNA Biochemistry and Biotechnology , pp. 303-314
    • Krzyzosiak, W.J.1    Napierala, M.2    Drozdz, M.3
  • 32
    • 0002287019 scopus 로고    scopus 로고
    • Algorithms and thermodynamics for RNA secondary structure prediction: A practical guide
    • Barciszewski,J. and Clark,B.F.C. (eds), Kluwer, Dordrecht, The Netherlands
    • Zuker,M., Mathews,D.H. and Turner,D.H. (1999) Algorithms and thermodynamics for RNA secondary structure prediction: a practical guide. In Barciszewski,J. and Clark,B.F.C. (eds), RNA Biochemistry and Biotechnology. Kluwer, Dordrecht, The Netherlands, pp. 11-43.
    • (1999) RNA Biochemistry and Biotechnology , pp. 11-43
    • Zuker, M.1    Mathews, D.H.2    Turner, D.H.3
  • 33
    • 0033591465 scopus 로고    scopus 로고
    • Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
    • Mathews,D.H., Sabina,J., Zuker,M. and Turner,D.H. (1999) Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J. Mol. Biol., 288, 911-940.
    • (1999) J. Mol. Biol. , vol.288 , pp. 911-940
    • Mathews, D.H.1    Sabina, J.2    Zuker, M.3    Turner, D.H.4
  • 35
    • 0344320243 scopus 로고    scopus 로고
    • Classical and novel chemical tools for RNA structure probing
    • Sool,D., Nishimura,S. and Moor,P.B. (eds), Pergamon, Amsterdam, The Netherlands
    • Giege,R., Helm,M. and Florentz,C. (2001) Classical and novel chemical tools for RNA structure probing. In Sool,D., Nishimura,S. and Moor,P.B. (eds), RNA. Pergamon, Amsterdam, The Netherlands, pp. 71-90.
    • (2001) RNA , pp. 71-90
    • Giege, R.1    Helm, M.2    Florentz, C.3
  • 36
    • 0024297759 scopus 로고
    • Characterization of the lead(II)-induced cleavages in tRNAs in solution and effect of the Y-base removal in yeast tRNAPhe
    • Krzyzosiak,W.J., Marciniec,T., Wiewiorowski,M., Romby,P., Ebel,J.P. and Giege,R. (1988) Characterization of the lead(II)-induced cleavages in tRNAs in solution and effect of the Y-base removal in yeast tRNAPhe. Biochemistry, 27, 5771-5777.
    • (1988) Biochemistry , vol.27 , pp. 5771-5777
    • Krzyzosiak, W.J.1    Marciniec, T.2    Wiewiorowski, M.3    Romby, P.4    Ebel, J.P.5    Giege, R.6
  • 38
    • 0022433369 scopus 로고
    • Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA
    • Brown,R.S., Dewan,J.C. and Klug,A. (1985) Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA. Biochemistry, 24, 4785-4801.
    • (1985) Biochemistry , vol.24 , pp. 4785-4801
    • Brown, R.S.1    Dewan, J.C.2    Klug, A.3
  • 40
    • 0034666143 scopus 로고    scopus 로고
    • A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator
    • Good,P.J., Chen,Q., Warner,S.J. and Herring,D.C. (2000) A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator. J. Biol. Chem., 275, 28583-28592.
    • (2000) J. Biol. Chem. , vol.275 , pp. 28583-28592
    • Good, P.J.1    Chen, Q.2    Warner, S.J.3    Herring, D.C.4
  • 41
    • 0035146628 scopus 로고    scopus 로고
    • The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing
    • Ladd,A.N., Charlet,N. and Cooper,T.A. (2001) The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing. Mol. Cell. Biol., 21, 1285-1296.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1285-1296
    • Ladd, A.N.1    Charlet, N.2    Cooper, T.A.3
  • 42
    • 0036193474 scopus 로고    scopus 로고
    • Regulation of alternative splicing of alpha-actinin transcript by Bruno-like proteins
    • Suzuki,H., Jin,Y., Otani,H., Yasuda,K. and Inoue,K. (2002) Regulation of alternative splicing of alpha-actinin transcript by Bruno-like proteins. Genes Cells, 7, 133-141.
    • (2002) Genes Cells , vol.7 , pp. 133-141
    • Suzuki, H.1    Jin, Y.2    Otani, H.3    Yasuda, K.4    Inoue, K.5
  • 45
    • 0035394801 scopus 로고    scopus 로고
    • In vivo co-localisation of MBNL protein with DMPK expanded-repeat transcripts
    • Fardaei,M., Larkin,K., Brook,J.D. and Hamshere,M.G. (2001) In vivo co-localisation of MBNL protein with DMPK expanded-repeat transcripts. Nucleic Acids Res., 29, 2766-2771.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 2766-2771
    • Fardaei, M.1    Larkin, K.2    Brook, J.D.3    Hamshere, M.G.4
  • 47
    • 0036537492 scopus 로고    scopus 로고
    • Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells
    • Fardaei,M., Rogers,M.T., Thorpe,H.M., Larkin,K., Hamshere,M.G., Harper,P.S. and Brook,J.D. (2002) Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells. Hum. Mol. Genet., 11, 805-814.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 805-814
    • Fardaei, M.1    Rogers, M.T.2    Thorpe, H.M.3    Larkin, K.4    Hamshere, M.G.5    Harper, P.S.6    Brook, J.D.7
  • 49
    • 0031941447 scopus 로고    scopus 로고
    • The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure
    • Bidichandani,S.I., Ashizawa,T. and Patel,P.I. (1998) The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure. Am. J. Hum. Genet., 62, 111-121.
    • (1998) Am. J. Hum. Genet. , vol.62 , pp. 111-121
    • Bidichandani, S.I.1    Ashizawa, T.2    Patel, P.I.3
  • 51
    • 0035920101 scopus 로고    scopus 로고
    • Sticky DNA, a self-associated complex formed at long GAA*TTC repeats in intron 1 of the frataxin gene, inhibits transcription
    • Sakamoto,N., Ohshima,K., Montermini,L., Pandolfo,M. and Wells,R.D. (2001) Sticky DNA, a self-associated complex formed at long GAA*TTC repeats in intron 1 of the frataxin gene, inhibits transcription. J. Biol. Chem., 276, 27171-27177.
    • (2001) J. Biol. Chem. , vol.276 , pp. 27171-27177
    • Sakamoto, N.1    Ohshima, K.2    Montermini, L.3    Pandolfo, M.4    Wells, R.D.5
  • 52
    • 0034612992 scopus 로고    scopus 로고
    • Unexpected formation of parallel duplex in GAA and TTC trinucleotide repeats of Friedreich's ataxia
    • LeProust,E.M., Pearson,C.E., Sinden,R.R. and Gao,X. (2000) Unexpected formation of parallel duplex in GAA and TTC trinucleotide repeats of Friedreich's ataxia. J. Mol. Biol., 302, 1063-1080.
    • (2000) J. Mol. Biol. , vol.302 , pp. 1063-1080
    • LeProust, E.M.1    Pearson, C.E.2    Sinden, R.R.3    Gao, X.4
  • 53
    • 0037462828 scopus 로고    scopus 로고
    • Hairpin formation in Friedreich's ataxia triplet repeat expansion
    • Heidenfelder,B.L., Makhov,A.M. and Topal,M.D. (2003) Hairpin formation in Friedreich's ataxia triplet repeat expansion. J. Biol. Chem., 278, 2425-2431.
    • (2003) J. Biol. Chem. , vol.278 , pp. 2425-2431
    • Heidenfelder, B.L.1    Makhov, A.M.2    Topal, M.D.3
  • 54
    • 0032478506 scopus 로고    scopus 로고
    • Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing
    • Tacke,R., Tohyama,M., Ogawa,S. and Manley,J.L. (1998) Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing. Cell, 93, 139-148.
    • (1998) Cell , vol.93 , pp. 139-148
    • Tacke, R.1    Tohyama, M.2    Ogawa, S.3    Manley, J.L.4


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