Why the drosophila shaker K+ channel is not a good model for ligand binding to voltage-gated Kv1 channels

Biochemistry

Volumn 52, Issue 9, 2013, Pages 1631-1640

  Mahdavi, Somayeh ^a   Kuyucak, Serdar ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING FREE ENERGY; BINDING MODES; COMPLEX MODEL; COMPLEX STRUCTURE; CONOTOXINS; HIGH AFFINITY; ION PERMEATION; LIGAND BINDING; MD SIMULATION; MOLECULAR DYNAMICS SIMULATIONS; POTASSIUM CHANNELS; POTENTIAL OF MEAN FORCE; UMBRELLA SAMPLING; VOLTAGE-GATED POTASSIUM CHANNELS;

BINDING ENERGY; BIOPHYSICS; CLONING; MOLECULAR DYNAMICS; POTASSIUM;

LIGANDS;

CONOTOXIN; KAPPA CONOTOXIN PVIIA; SHAKER POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; DROSOPHILA; HUMAN; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MUTAGENESIS; MUTATION; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; CONOTOXINS; DROSOPHILA; DROSOPHILA PROTEINS; KV1.1 POTASSIUM CHANNEL; KV1.2 POTASSIUM CHANNEL; LIGANDS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; RATS; SEQUENCE ALIGNMENT; SHAKER SUPERFAMILY OF POTASSIUM CHANNELS; THERMODYNAMICS;

EID: 84874604503     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi301257p     Document Type: Article

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