-
1
-
-
0027109075
-
Cancer. p53, guardian of the genome
-
PMID:1614522
-
Lane DP. Cancer. p53, guardian of the genome. Nature 1992; 358:15-6; PMID:1614522; http://dx.doi. org/10.1038/358015a0
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
2
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
PMID:9039259
-
Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997; 88:323-31; PMID:9039259; http://dx.doi.org/10.1016/S0092-8674(00)81871-1
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
3
-
-
0036674617
-
Live or let die: The cell's response to p53
-
PMID:12154352
-
Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer 2002; 2:594-604; PMID:12154352; http://dx.doi.org/10.1038/nrc864
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
4
-
-
79955751752
-
Metabolic regulation by p53
-
PMID:21340684
-
Maddocks OD, Vousden KH. Metabolic regulation by p53. J Mol Med (Berl) 2011; 89:237-45; PMID:21340684; http://dx.doi.org/10.1007/s00109-011-0735-5
-
(2011)
J Mol Med (Berl)
, vol.89
, pp. 237-245
-
-
Maddocks, O.D.1
Vousden, K.H.2
-
5
-
-
77953384831
-
Tumor suppressive functions of p53
-
PMID:20066118
-
Zilfou JT, Lowe SW. Tumor suppressive functions of p53. Cold Spring Harb Perspect Biol 2009; 1:a001883; PMID:20066118; http://dx.doi.org/10.1101/ cshperspect. a001883
-
(2009)
Cold Spring Harb Perspect Biol
, vol.1
-
-
Zilfou, J.T.1
Lowe, S.W.2
-
6
-
-
84864040884
-
Dysregulation of glucose transport, glycolysis, TCA cycle and glutaminolysis by oncogenes and tumor suppressors in cancer cells
-
PMID:22750268
-
Chen JQ, Russo J. Dysregulation of glucose transport, glycolysis, TCA cycle and glutaminolysis by oncogenes and tumor suppressors in cancer cells. Biochim Biophys Acta 2012; 1826:370-84; PMID:22750268
-
(2012)
Biochim Biophys Acta
, vol.1826
, pp. 370-384
-
-
Chen, J.Q.1
Russo, J.2
-
7
-
-
33745149291
-
P53 regulates mitochondrial respiration
-
PMID:16728594
-
Matoba S, Kang JG, Patino WD, Wragg A, Boehm M, Gavrilova O, et al. p53 regulates mitochondrial respiration. Science 2006; 312:1650-3; PMID:16728594; http://dx.doi.org/10.1126/science.1126863
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
-
8
-
-
1942506067
-
The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression
-
PMID:15059920
-
Schwartzenberg-Bar-Yoseph F, Armoni M, Karnieli E. The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression. Cancer Res 2004; 64:2627-33; PMID:15059920; http://dx.doi.org/10.1158/0008-5472.CAN-03- 0846
-
(2004)
Cancer Res
, vol.64
, pp. 2627-2633
-
-
Schwartzenberg-Bar-Yoseph, F.1
Armoni, M.2
Karnieli, E.3
-
9
-
-
84855878565
-
P53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
-
PMID:22123926
-
Contractor T, Harris CR. p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2. Cancer Res 2012; 72:560-7; PMID:22123926; http://dx.doi.org/10.1158/0008-5472.CAN-11-1215
-
(2012)
Cancer Res
, vol.72
, pp. 560-567
-
-
Contractor, T.1
Harris, C.R.2
-
10
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
PMID:16839880
-
Bensaad K, Tsuruta A, Selak MA, Vidal MN, Nakano K, Bartrons R, et al. TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 2006; 126:107-20; PMID:16839880; http://dx.doi.org/10.1016/j. cell.2006.05.036
-
(2006)
Cell
, vol.126
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
Vidal, M.N.4
Nakano, K.5
Bartrons, R.6
-
11
-
-
77952212178
-
Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
-
PMID:20378837
-
Hu W, Zhang C, Wu R, Sun Y, Levine A, Feng Z. Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function. Proc Natl Acad Sci U S A 2010; 107:7455-60; PMID:20378837; http://dx.doi.org/10.1073/pnas. 1001006107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 7455-7460
-
-
Hu, W.1
Zhang, C.2
Wu, R.3
Sun, Y.4
Levine, A.5
Feng, Z.6
-
12
-
-
77952227625
-
Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species
-
PMID:20351271
-
Suzuki S, Tanaka T, Poyurovsky MV, Nagano H, Mayama T, Ohkubo S, et al. Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species. Proc Natl Acad Sci U S A 2010; 107:7461-6; PMID:20351271; http://dx.doi.org/10.1073/pnas.1002459107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 7461-7466
-
-
Suzuki, S.1
Tanaka, T.2
Poyurovsky, M.V.3
Nagano, H.4
Mayama, T.5
Ohkubo, S.6
-
13
-
-
20844449238
-
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
-
PMID:15866171
-
Jones RG, Plas DR, Kubek S, Buzzai M, Mu J, Xu Y, et al. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell 2005; 18:283-93; PMID:15866171; http://dx.doi.org/10.1016/j.molcel. 2005.03.027
-
(2005)
Mol Cell
, vol.18
, pp. 283-293
-
-
Jones, R.G.1
Plas, D.R.2
Kubek, S.3
Buzzai, M.4
Mu, J.5
Xu, Y.6
-
14
-
-
42949152052
-
Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress
-
PMID:18056705
-
Okoshi R, Ozaki T, Yamamoto H, Ando K, Koida N, Ono S, et al. Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress. J Biol Chem 2008; 283:3979-87; PMID:18056705; http://dx.doi. org/10.1074/jbc.M705232200
-
(2008)
J Biol Chem
, vol.283
, pp. 3979-3987
-
-
Okoshi, R.1
Ozaki, T.2
Yamamoto, H.3
Ando, K.4
Koida, N.5
Ono, S.6
-
15
-
-
78649833334
-
P53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation
-
PMID:20937856
-
Scherz-Shouval R, Weidberg H, Gonen C, Wilder S, Elazar Z, Oren M. p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation. Proc Natl Acad Sci U S A 2010; 107:18511-6; PMID:20937856; http://dx.doi. org/10.1073/pnas.1006124107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 18511-18516
-
-
Scherz-Shouval, R.1
Weidberg, H.2
Gonen, C.3
Wilder, S.4
Elazar, Z.5
Oren, M.6
-
16
-
-
0020130867
-
Regulation of the biosynthesis of CoA at the level of pantothenate kinase
-
PMID:7084227
-
Halvorsen O, Skrede S. Regulation of the biosynthesis of CoA at the level of pantothenate kinase. Eur J Biochem 1982; 124:211-5; PMID:7084227; http://dx.doi.org/10.1111/j.1432-1033.1982.tb05927.x
-
(1982)
Eur J Biochem
, vol.124
, pp. 211-215
-
-
Halvorsen, O.1
Skrede, S.2
-
17
-
-
0019812065
-
Regulation of coenzyme A biosynthesis
-
PMID:6796563
-
Jackowski S, Rock CO. Regulation of coenzyme A biosynthesis. J Bacteriol 1981; 148:926-32; PMID:6796563
-
(1981)
J Bacteriol
, vol.148
, pp. 926-932
-
-
Jackowski, S.1
Rock, C.O.2
-
19
-
-
0842304656
-
PPARalpha controls the intracellular coenzyme A concentration via regulation of PANK1alpha gene expression
-
PMID:14523052
-
Ramaswamy G, Karim MA, Murti KG, Jackowski S. PPARalpha controls the intracellular coenzyme A concentration via regulation of PANK1alpha gene expression. J Lipid Res 2004; 45:17-31; PMID:14523052; http://dx.doi.org/10. 1194/jlr.M300279-JLR200
-
(2004)
J Lipid Res
, vol.45
, pp. 17-31
-
-
Ramaswamy, G.1
Karim, M.A.2
Murti, K.G.3
Jackowski, S.4
-
20
-
-
77956223798
-
Pantothenate kinase 1 is required to support the metabolic transition from the fed to the fasted state
-
PMID:20559429
-
Leonardi R, Rehg JE, Rock CO, Jackowski S. Pantothenate kinase 1 is required to support the metabolic transition from the fed to the fasted state. PLoS One 2010; 5:e11107; PMID:20559429; http://dx.doi. org/10.1371/journal.pone. 0011107
-
(2010)
PLoS One
, vol.5
-
-
Leonardi, R.1
Rehg, J.E.2
Rock, C.O.3
Jackowski, S.4
-
21
-
-
70449093664
-
GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress
-
PMID:19917247
-
Ide T, Brown-Endres L, Chu K, Ongusaha PP, Ohtsuka T, El-Deiry WS, et al. GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress. Mol Cell 2009; 36:379-92; PMID:19917247; http://dx.doi.org/10.1016/j.molcel. 2009.09.031
-
(2009)
Mol Cell
, vol.36
, pp. 379-392
-
-
Ide, T.1
Brown-Endres, L.2
Chu, K.3
Ongusaha, P.P.4
Ohtsuka, T.5
El-Deiry, W.S.6
-
22
-
-
0038727567
-
Alterations in the DNA binding activity of transcriptional factors activator protein-1, Sp1, and hepatocyte nuclear factor-1 in rat jejunum during starvation and refeeding
-
PMID:12753154
-
Ihara T, Tsujikawa T, Fujiyama Y, Bamba T. Alterations in the DNA binding activity of transcriptional factors activator protein-1, Sp1, and hepatocyte nuclear factor-1 in rat jejunum during starvation and refeeding. J Gastroenterol Hepatol 2003; 18:705-11; PMID:12753154; http://dx.doi.org/10.1046/j.1440-1746. 2003.02924.x
-
(2003)
J Gastroenterol Hepatol
, vol.18
, pp. 705-711
-
-
Ihara, T.1
Tsujikawa, T.2
Fujiyama, Y.3
Bamba, T.4
-
23
-
-
0346435098
-
Downregulation of Sp1 activity through modulation of O-glycosylation by treatment with a low glucose mimetic, 2-deoxyglucose
-
PMID:14532290
-
Kang HT, Ju JW, Cho JW, Hwang ES. Downregulation of Sp1 activity through modulation of O-glycosylation by treatment with a low glucose mimetic, 2-deoxyglucose. J Biol Chem 2003; 278:51223-31; PMID:14532290; http://dx.doi. org/10.1074/jbc.M307332200
-
(2003)
J Biol Chem
, vol.278
, pp. 51223-51231
-
-
Kang, H.T.1
Ju, J.W.2
Cho, J.W.3
Hwang, E.S.4
-
24
-
-
67649866042
-
Thiazolidinediones mimic glucose starvation in facilitating Sp1 degradation through the up-regulation of beta-transducin repeatcontaining protein
-
PMID:19372209
-
Wei S, Chuang HC, Tsai WC, Yang HC, Ho SR, Paterson AJ, et al. Thiazolidinediones mimic glucose starvation in facilitating Sp1 degradation through the up-regulation of beta-transducin repeatcontaining protein. Mol Pharmacol 2009; 76:47-57; PMID:19372209; http://dx.doi.org/10.1124/mol.109. 055376
-
(2009)
Mol Pharmacol
, vol.76
, pp. 47-57
-
-
Wei, S.1
Chuang, H.C.2
Tsai, W.C.3
Yang, H.C.4
Ho, S.R.5
Paterson, A.J.6
-
25
-
-
33845668241
-
Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis
-
PMID:17189186
-
Tang Y, Luo J, Zhang W, Gu W. Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell 2006; 24:827-39; PMID:17189186; http://dx.doi.org/10.1016/j. molcel.2006.11.021
-
(2006)
Mol Cell
, vol.24
, pp. 827-839
-
-
Tang, Y.1
Luo, J.2
Zhang, W.3
Gu, W.4
-
26
-
-
43049163953
-
Acetylation is indispensable for p53 activation
-
PMID:18485870
-
Tang Y, Zhao W, Chen Y, Zhao Y, Gu W. Acetylation is indispensable for p53 activation. Cell 2008; 133:612-26; PMID:18485870; http://dx.doi.org/10.1016/ j. cell.2008.03.025
-
(2008)
Cell
, vol.133
, pp. 612-626
-
-
Tang, Y.1
Zhao, W.2
Chen, Y.3
Zhao, Y.4
Gu, W.5
-
27
-
-
0023664065
-
Regulation of pantothenate kinase by coenzyme A and its thioesters
-
PMID:3029083
-
Vallari DS, Jackowski S, Rock CO. Regulation of pantothenate kinase by coenzyme A and its thioesters. J Biol Chem 1987; 262:2468-71; PMID:3029083
-
(1987)
J Biol Chem
, vol.262
, pp. 2468-2471
-
-
Vallari, D.S.1
Jackowski, S.2
Rock, C.O.3
|