메뉴 건너뛰기




Volumn 26, Issue 11, 2012, Pages

Targeted therapy: Its status and promise in selected solid tumors part II

Author keywords

[No Author keywords available]

Indexed keywords

AFLIBERCEPT; ANTINEOPLASTIC AGENT; AROMATASE INHIBITOR; BEVACIZUMAB; CARBOPLATIN; CETUXIMAB; CISPLATIN; CRIZOTINIB; DOCETAXEL; DOXORUBICIN; ERLOTINIB; EVEROLIMUS; FLUOROURACIL; FOLINIC ACID; GEFITINIB; GEMCITABINE; IPILIMUMAB; IRINOTECAN; LAPATINIB; OXALIPLATIN; PACLITAXEL; PANITUMUMAB; PERTUZUMAB; PLACEBO; PROTEIN TYROSINE KINASE INHIBITOR; REGORAFENIB; TOPOTECAN; TRASTUZUMAB; TRASTUZUMAB EMTANSINE;

EID: 84874589478     PISSN: 08909091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (9)

References (59)
  • 1
    • 79957443342 scopus 로고    scopus 로고
    • Abiraterone and increased survival in metastatic prostate cancer
    • de Bono JS, Logothetis CJ, Molina A, et al. Abiraterone and increased survival in metastatic prostate cancer. N Engl J Med. 2011;364:1995-2005.
    • (2011) N Engl J Med. , vol.364 , pp. 1995-2005
    • de Bono, J.S.1    Logothetis, C.J.2    Molina, A.3
  • 2
    • 77952105685 scopus 로고    scopus 로고
    • Antitumour activity of MDV3100 in castration-resistant prostate cancer: A phase 1-2 study
    • Scher HI, Beer TM, Higano CS, et al. Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study. Lancet. 2010;375:1437-46.
    • (2010) Lancet , vol.375 , pp. 1437-1446
    • Scher, H.I.1    Beer, T.M.2    Higano, C.S.3
  • 3
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • Kantoff PW, Higano CS, Shore ND, et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med. 2010;363:411-22.
    • (2010) N Engl J Med. , vol.363 , pp. 411-422
    • Kantoff, P.W.1    Higano, C.S.2    Shore, N.D.3
  • 4
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
    • Bang YJ, Van Cutsem E, Feyereislova A, et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet. 2010;376:687-97.
    • (2010) Lancet , vol.376 , pp. 687-697
    • Bang, Y.J.1    van Cutsem, E.2    Feyereislova, A.3
  • 5
    • 79951671750 scopus 로고
    • Estrogen-binding substances of target tissue
    • Jensen EV, Desombre ER, Kawashima T, et al. Estrogen-binding substances of target tissue. Science. 1967;158:529-30.
    • (1967) Science , vol.158 , pp. 529-530
    • Jensen, E.V.1    Desombre, E.R.2    Kawashima, T.3
  • 6
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature. 2000;406:747-52.
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 7
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science. 1987;235:177-82.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 8
    • 84861516765 scopus 로고    scopus 로고
    • Intrinsic and acquired resistance to HER2-targeted therapies in HER2 gene-amplified breast cancer: Mechanisms and clinical implications
    • Rexer BN, Arteaga CL. Intrinsic and acquired resistance to HER2-targeted therapies in HER2 gene-amplified breast cancer: mechanisms and clinical implications. Crit Rev Oncog. 2012;17:1-16.
    • (2012) Crit Rev Oncog. , vol.17 , pp. 1-16
    • Rexer, B.N.1    Arteaga, C.L.2
  • 9
    • 84863078767 scopus 로고    scopus 로고
    • Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer
    • Baselga J, Campone M, Piccart M, et al. Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer. N Engl J Med. 2012;366:520-9.
    • (2012) N Engl J Med. , vol.366 , pp. 520-529
    • Baselga, J.1    Campone, M.2    Piccart, M.3
  • 10
    • 26844457534 scopus 로고    scopus 로고
    • The distinctive nature of HER2-positive breast cancers
    • Burstein HJ. The distinctive nature of HER2-positive breast cancers. N Engl J Med. 2005;353:1652-4.
    • (2005) N Engl J Med. , vol.353 , pp. 1652-1654
    • Burstein, H.J.1
  • 11
    • 84862914692 scopus 로고    scopus 로고
    • Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
    • Baselga J, Cortes J, Kim SB, et al. Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med. 2012;366:109-19.
    • (2012) N Engl J Med. , vol.366 , pp. 109-119
    • Baselga, J.1    Cortes, J.2    Kim, S.B.3
  • 12
    • 80054098573 scopus 로고    scopus 로고
    • Antibody conjugate therapeutics: Challenges and potential
    • Teicher BA, Chari RV. Antibody conjugate therapeutics: challenges and potential. Clin Cancer Res. 2011;17:6389-97.
    • (2011) Clin Cancer Res. , vol.17 , pp. 6389-6397
    • Teicher, B.A.1    Chari, R.V.2
  • 13
    • 0036554863 scopus 로고    scopus 로고
    • Anti-HER2 immunoliposomes: Enhanced efficacy attributable to targeted delivery
    • Park JW, Hong K, Kirpotin DB, et al. Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery. Clin Cancer Res. 2002;8:1172-81.
    • (2002) Clin Cancer Res. , vol.8 , pp. 1172-1181
    • Park, J.W.1    Hong, K.2    Kirpotin, D.B.3
  • 14
    • 0015379932 scopus 로고
    • Intensive combined chemotherapy and radiotherapy in patients with nonresectable bronchogenic carcinoma
    • Hansen HH, Muggia FM, Andrews R, Selawry OS. Intensive combined chemotherapy and radiotherapy in patients with nonresectable bronchogenic carcinoma. Cancer. 1972;30:315-24.
    • (1972) Cancer , vol.30 , pp. 315-324
    • Hansen, H.H.1    Muggia, F.M.2    Andrews, R.3    Selawry, O.S.4
  • 15
    • 0020471997 scopus 로고
    • Experience of the National Cancer Institute (USA) in the treatment and biology of small cell lung cancer
    • Minna JD, Bunn PA, Jr., Carney DN, et al. Experience of the National Cancer Institute (USA) in the treatment and biology of small cell lung cancer. Bull Cancer. 1982;69:83-93.
    • (1982) Bull Cancer. , vol.69 , pp. 83-93
    • Minna, J.D.1    Bunn Jr., P.A.2    Carney, D.N.3
  • 16
    • 70349376330 scopus 로고    scopus 로고
    • Molecular predictive and prognostic markers in non-small-cell lung cancer
    • Coate LE, John T, Tsao MS, Shepherd FA. Molecular predictive and prognostic markers in non-small-cell lung cancer. Lancet Oncol. 2009;10:1001-10.
    • (2009) Lancet Oncol. , vol.10 , pp. 1001-1010
    • Coate, L.E.1    John, T.2    Tsao, M.S.3    Shepherd, F.A.4
  • 17
    • 0012381722 scopus 로고    scopus 로고
    • Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced nonsmall-cell lung cancer (the IDEAL 1 trial)
    • Fukuoka M, Yano S, Giaccone G, et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced nonsmall-cell lung cancer (the IDEAL 1 trial). J Clin Oncol. 2003;21:2237-46.
    • (2003) J Clin Oncol. , vol.21 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3
  • 18
    • 78049425319 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
    • Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med. 2010;363:1693-703.
    • (2010) N Engl J Med. , vol.363 , pp. 1693-1703
    • Kwak, E.L.1    Bang, Y.J.2    Camidge, D.R.3
  • 19
    • 84866258767 scopus 로고    scopus 로고
    • Genetic and biochemical alterations in non-small cell lung cancer
    • Johnson JL, Pillai S, Chellappan SP. Genetic and biochemical alterations in non-small cell lung cancer. Biochem Res Int. 2012;2012:940405.
    • (2012) Biochem Res Int. , vol.2012 , pp. 940405
    • Johnson, J.L.1    Pillai, S.2    Chellappan, S.P.3
  • 20
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med. 2009;361:947-57.
    • (2009) N Engl J Med. , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 21
    • 79960889662 scopus 로고    scopus 로고
    • Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study
    • Zhou C, Wu YL, Chen G, et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol. 2011;12:735-42.
    • (2011) Lancet Oncol. , vol.12 , pp. 735-742
    • Zhou, C.1    Wu, Y.L.2    Chen, G.3
  • 22
    • 80053386829 scopus 로고    scopus 로고
    • Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: A retrospective analysis
    • Shaw AT, Yeap BY, Solomon BJ, et al. Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. Lancet Oncol. 2011;12:1004-12.
    • (2011) Lancet Oncol. , vol.12 , pp. 1004-1012
    • Shaw, A.T.1    Yeap, B.Y.2    Solomon, B.J.3
  • 23
    • 65349116059 scopus 로고    scopus 로고
    • Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): An open-label randomised phase III trial
    • Pirker R, Pereira JR, Szczesna A, et al. Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial. Lancet. 2009;373:1525-31.
    • (2009) Lancet , vol.373 , pp. 1525-1531
    • Pirker, R.1    Pereira, J.R.2    Szczesna, A.3
  • 26
    • 33746875641 scopus 로고    scopus 로고
    • A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer
    • Potti A, Mukherjee S, Petersen R, et al. A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med. 2006;355:570-80.
    • (2006) N Engl J Med. , vol.355 , pp. 570-580
    • Potti, A.1    Mukherjee, S.2    Petersen, R.3
  • 27
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 1990;61:759-67.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 28
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med. 1971;285:1182-6.
    • (1971) N Engl J Med. , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 29
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell. 1996;86:353-64.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 30
    • 0036469151 scopus 로고    scopus 로고
    • Relevance of biologic markers in colorectal carcinoma: A comparative study of a broad panel
    • Barozzi C, Ravaioli M, D'Errico A, et al. Relevance of biologic markers in colorectal carcinoma: a comparative study of a broad panel. Cancer. 2002;94:647-57.
    • (2002) Cancer , vol.94 , pp. 647-657
    • Barozzi, C.1    Ravaioli, M.2    D'Errico, A.3
  • 31
    • 33845337061 scopus 로고    scopus 로고
    • Tumour-associated angiogenesis in human colorectal cancer
    • Rmali KA, Puntis MC, Jiang WG. Tumour-associated angiogenesis in human colorectal cancer. Colorectal Dis. 2007;9:3-14.
    • (2007) Colorectal Dis. , vol.9 , pp. 3-14
    • Rmali, K.A.1    Puntis, M.C.2    Jiang, W.G.3
  • 32
    • 0035884231 scopus 로고    scopus 로고
    • The epidermal growth factor receptor: From mutant oncogene in nonhuman cancers to therapeutic target in human neoplasia
    • Arteaga CL. The epidermal growth factor receptor: from mutant oncogene in nonhuman cancers to therapeutic target in human neoplasia. J Clin Oncol. 2001;19:32S-40S.
    • (2001) J Clin Oncol. , vol.19
    • Arteaga, C.L.1
  • 33
    • 77953626157 scopus 로고    scopus 로고
    • Biology of colorectal cancer
    • Saif MW, Chu E. Biology of colorectal cancer. Cancer J. 2010;16:196-201.
    • (2010) Cancer J. , vol.16 , pp. 196-201
    • Saif, M.W.1    Chu, E.2
  • 34
    • 63849088630 scopus 로고    scopus 로고
    • Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
    • Van Cutsem E, Kohne CH, Hitre E, et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med. 2009;360:1408-17.
    • (2009) N Engl J Med. , vol.360 , pp. 1408-1417
    • Van Cutsem, E.1    Kohne, C.H.2    Hitre, E.3
  • 35
    • 79956298812 scopus 로고    scopus 로고
    • Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: Updated analysis of overall survival according to tumor KRAS and BRAF mutation status
    • Van Cutsem E, Kohne CH, Lang I, et al. Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status. J Clin Oncol. 2011; 29:2011-9.
    • (2011) J Clin Oncol. , vol.29 , pp. 2011-2019
    • Van Cutsem, E.1    Kohne, C.H.2    Lang, I.3
  • 36
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med. 2004;351:337-45.
    • (2004) N Engl J Med. , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 37
    • 84874633149 scopus 로고    scopus 로고
    • Regorafenib in metastatic colorectal cancer
    • Grothy A. Regorafenib in metastatic colorectal cancer. Clin Adv Hematol Oncol. 2012;10:324-5.
    • (2012) Clin Adv Hematol Oncol. , vol.10 , pp. 324-325
    • Grothy, A.1
  • 38
    • 0032851163 scopus 로고    scopus 로고
    • Interleukin 2 gene therapy of colorectal carcinoma with autologous irradiated tumor cells and genetically engineered fibroblasts: A Phase I study
    • Sobol RE, Shawler DL, Carson C, et al. Interleukin 2 gene therapy of colorectal carcinoma with autologous irradiated tumor cells and genetically engineered fibroblasts: a Phase I study. Clin Cancer Res. 1999;5:2359-65.
    • (1999) Clin Cancer Res. , vol.5 , pp. 2359-2365
    • Sobol, R.E.1    Shawler, D.L.2    Carson, C.3
  • 39
    • 33847407907 scopus 로고    scopus 로고
    • A pilot study of CTLA-4 blockade after cancer vaccine failure in patients with advanced malignancy
    • O'Mahony D, Morris JC, Quinn C, et al. A pilot study of CTLA-4 blockade after cancer vaccine failure in patients with advanced malignancy. Clin Cancer Res. 2007;13:958-64.
    • (2007) Clin Cancer Res. , vol.13 , pp. 958-964
    • O'Mahony, D.1    Morris, J.C.2    Quinn, C.3
  • 40
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. Integrated genomic analyses of ovarian carcinoma. Nature. 2011;474:609-15.
    • (2011) Nature , vol.474 , pp. 609-615
  • 41
    • 84867872838 scopus 로고    scopus 로고
    • National Cancer Institute. Available from: Accessed October 25, 2012
    • National Cancer Institute. Ovarian epithelial cancer treatment (PDQ). Available from: http://www.cancer.gov/cancertopics/pdq/treatment/ovarianepithelial/HealthProfessional/page5. Accessed October 25, 2012.
    • Ovarian epithelial cancer treatment (PDQ)
  • 42
    • 13444269246 scopus 로고    scopus 로고
    • Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer
    • Dinulescu DM, Ince TA, Quade BJ, et al. Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer. Nat Med. 2005;11:63-70.
    • (2005) Nat Med. , vol.11 , pp. 63-70
    • Dinulescu, D.M.1    Ince, T.A.2    Quade, B.J.3
  • 43
    • 80053965905 scopus 로고    scopus 로고
    • BRCA mutation status and determinant of outcome in women with recurrent epithelial ovarian cancer treated with pegylated liposomal doxorubicin
    • Safra T, Borgato L, Nicoletto MO, et al. BRCA mutation status and determinant of outcome in women with recurrent epithelial ovarian cancer treated with pegylated liposomal doxorubicin. Mol Cancer Ther. 2011;10:2000-7.
    • (2011) Mol Cancer Ther. , vol.10 , pp. 2000-2007
    • Safra, T.1    Borgato, L.2    Nicoletto, M.O.3
  • 44
    • 17244373777 scopus 로고    scopus 로고
    • Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
    • Farmer H, McCabe N, Lord CJ, et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature. 2005;434:917-21.
    • (2005) Nature , vol.434 , pp. 917-921
    • Farmer, H.1    McCabe, N.2    Lord, C.J.3
  • 45
    • 17244375049 scopus 로고    scopus 로고
    • Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
    • Bryant HE, Schultz N, Thomas HD, et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature. 2005;434:913-7.
    • (2005) Nature , vol.434 , pp. 913-917
    • Bryant, H.E.1    Schultz, N.2    Thomas, H.D.3
  • 46
    • 81155152247 scopus 로고    scopus 로고
    • PARP inhibitors in BRCA gene-mutated ovarian cancer and beyond
    • Banerjee S, Kaye S. PARP inhibitors in BRCA gene-mutated ovarian cancer and beyond. Curr Oncol Rep. 2011;13:442-9.
    • (2011) Curr Oncol Rep. , vol.13 , pp. 442-449
    • Banerjee, S.1    Kaye, S.2
  • 47
    • 63549112177 scopus 로고    scopus 로고
    • Breast cancer arising in a BRCA-mutated background: Therapeutic implications from an animal model and drug development
    • Fasano J, Muggia F. Breast cancer arising in a BRCA-mutated background: therapeutic implications from an animal model and drug development. Ann Oncol. 2009;20:609-14.
    • (2009) Ann Oncol. , vol.20 , pp. 609-614
    • Fasano, J.1    Muggia, F.2
  • 48
    • 45749108933 scopus 로고    scopus 로고
    • How do real tumors become resistant to cisplatin?
    • Borst P, Rottenberg S, Jonkers J. How do real tumors become resistant to cisplatin? Cell Cycle. 2008;7:1353-9.
    • (2008) Cell Cycle. , vol.7 , pp. 1353-1359
    • Borst, P.1    Rottenberg, S.2    Jonkers, J.3
  • 49
    • 57649101120 scopus 로고    scopus 로고
    • Platinum compounds 30 years after the introduction of cisplatin: Implications for the treatment of ovarian cancer
    • Muggia F. Platinum compounds 30 years after the introduction of cisplatin: implications for the treatment of ovarian cancer. Gynecol Oncol. 2009;112:275-81.
    • (2009) Gynecol Oncol. , vol.112 , pp. 275-281
    • Muggia, F.1
  • 51
    • 84862275233 scopus 로고    scopus 로고
    • Exposure-response relationship of AMG 386 in combination with weekly paclitaxel in recurrent ovarian cancer and its implication for dose selection
    • Lu JF, Rasmussen E, Karlan BY, et al. Exposure-response relationship of AMG 386 in combination with weekly paclitaxel in recurrent ovarian cancer and its implication for dose selection. Cancer Chemother Pharmacol. 2012;69:1135-44.
    • (2012) Cancer Chemother Pharmacol. , vol.69 , pp. 1135-1144
    • Lu, J.F.1    Rasmussen, E.2    Karlan, B.Y.3
  • 52
    • 76349087360 scopus 로고    scopus 로고
    • Combination therapy: Intermittent sorafenib with bevacizumab yields activity and decreased toxicity
    • Lee JM, Sarosy GA, Annunziata CM, et al. Combination therapy: intermittent sorafenib with bevacizumab yields activity and decreased toxicity. Br J Cancer. 2010;102:495-9.
    • (2010) Br J Cancer. , vol.102 , pp. 495-499
    • Lee, J.M.1    Sarosy, G.A.2    Annunziata, C.M.3
  • 53
    • 49249113717 scopus 로고    scopus 로고
    • Challenges and pitfalls of combining targeted agents in phase I studies
    • Cannistra SA. Challenges and pitfalls of combining targeted agents in phase I studies. J Clin Oncol. 2008; 26:3665-7.
    • (2008) J Clin Oncol. , vol.26 , pp. 3665-3667
    • Cannistra, S.A.1
  • 54
    • 0037440042 scopus 로고    scopus 로고
    • Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: A phase II trial of the Gynecologic Oncology Group
    • Bookman MA, Darcy KM, Clarke-Pearson D, et al. Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a phase II trial of the Gynecologic Oncology Group. J Clin Oncol. 2003; 21:283-90.
    • (2003) J Clin Oncol. , vol.21 , pp. 283-290
    • Bookman, M.A.1    Darcy, K.M.2    Clarke-Pearson, D.3
  • 55
    • 83355166909 scopus 로고    scopus 로고
    • Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth
    • Yakes FM, Chen J, Tan J, et al. Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Mol Cancer Ther. 2011;10:2298-308.
    • (2011) Mol Cancer Ther. , vol.10 , pp. 2298-2308
    • Yakes, F.M.1    Chen, J.2    Tan, J.3
  • 56
    • 84874631515 scopus 로고    scopus 로고
    • Available from: Accessed October 31, 2012
    • Dizon DS. Redesigning studies: pushing the envelope. Available from: http://connection.asco.org/Commentary/Article/ID/3232/Redesigning-Studies-Pushing-the-Envelope.aspx. Accessed October 31, 2012.
    • Redesigning studies: Pushing the envelope
    • Dizon, D.S.1
  • 57
    • 42949105127 scopus 로고    scopus 로고
    • Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyteassociated antigen 4 in previously vaccinated cancer patients
    • Hodi FS, Butler M, Oble Da, et al. Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyteassociated antigen 4 in previously vaccinated cancer patients. Proc Natl Acad Sci USA. 2008;105:3005-10.
    • (2008) Proc Natl Acad Sci USA. , vol.105 , pp. 3005-3010
    • Hodi, F.S.1    Butler, M.2    Oble, D.3
  • 59
    • 40849147041 scopus 로고    scopus 로고
    • EGFR antagonists in cancer treatment
    • Ciardiello F, Tortora G. EGFR antagonists in cancer treatment. N Engl J Med. 2008;358:1160-1174.
    • (2008) N Engl J Med. , vol.358 , pp. 1160-1174
    • Ciardiello, F.1    Tortora, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.