A Novel Lipopeptide from Skin Commensal Activates TLR2/CD36-p38 MAPK Signaling to Increase Antibacterial Defense against Bacterial Infection

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Li, Dongqing ^a   Lei, Hu ^a   Li, Zhiheng ^a   Li, Hongquan ^a   Wang, Yue ^a   Lai, Yuping ^a  

^a EAST CHINA NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN 2; BETA DEFENSIN 3; LIPOPEPTIDE; LIPOPEPTIDE 01; MITOGEN ACTIVATED PROTEIN KINASE P38; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BETA DEFENSIN; CD36 ANTIGEN; TLR2 PROTEIN, HUMAN; TLR2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL INFECTION; BACTERIAL SURVIVAL; COMMENSAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG TREATMENT FAILURE; ESCHERICHIA COLI; GROWTH INHIBITION; KERATINOCYTE; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SKIN INFECTION; STAPHYLOCOCCUS EPIDERMIDIS; STAPHYLOCOCCUS INFECTION; STRUCTURE ACTIVITY RELATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; ENZYME ACTIVATION; HUMAN; LIVER; METABOLISM; MICROBIOLOGY; SIGNAL TRANSDUCTION; SKIN; STAPHYLOCOCCAL SKIN INFECTIONS; STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIGENS, CD36; BETA-DEFENSINS; CELLS, CULTURED; ENZYME ACTIVATION; HUMANS; KERATINOCYTES; LIPOPEPTIDES; LIVER; MAP KINASE SIGNALING SYSTEM; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SKIN; STAPHYLOCOCCAL SKIN INFECTIONS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; TOLL-LIKE RECEPTOR 2;

EID: 84874582026     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058288     Document Type: Article

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