Hepatocytes display a compensatory survival response against cadmium toxicity by a mechanism mediated by EGFR and Src

Toxicology in Vitro

Volumn 27, Issue 3, 2013, Pages 1031-1042

  Martinez Flores K ^a   Uribe Marin B C ^a   Souza Arroyo, V ^a   Bucio Ortiz, L ^a   Lopez Reyes A ^a,b   Gomez Quiroz L E ^a   Rojas del Castillo, E ^c   Gutierrez Ruiz M C ^a  

^a DEPARTAMENTO DE QUÍMICA   (Mexico)

^b INSTITUTO NACIONAL DE REHABILITACIÓN   (Mexico)

^c INSTITUTO DE INVESTIGACIONES BIOMÉDICAS   (Mexico)

Author keywords

Cadmium; EGFR; Erk; Metallothionein; NADPH oxidase; ROS; Src; Stat3

Indexed keywords

CADMIUM; CADMIUM CHLORIDE; EPIDERMAL GROWTH FACTOR RECEPTOR; METALLOTHIONEIN II; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN P53; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STAT3 PROTEIN; TYROSINE;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; CELL ISOLATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXICITY; DIMERIZATION; ENZYME ACTIVATION; ENZYME ACTIVITY; EXPOSURE; FLOW CYTOMETRY; IMMUNOPRECIPITATION; LIVER CELL; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CADMIUM; CELL SURVIVAL; CELLS, CULTURED; ENVIRONMENTAL POLLUTANTS; HEPATOCYTES; MALE; METALLOTHIONEIN; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SRC-FAMILY KINASES; STAT3 TRANSCRIPTION FACTOR;

EID: 84874575272     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2013.01.017     Document Type: Article

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