Nutrient deprivation induces the Warburg effect through ROS/AMPK-dependent activation of pyruvate dehydrogenase kinase

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1833, Issue 5, 2013, Pages 1147-1156

  Wu, Ching An ^a   Chao, Yee ^b   Shiah, Shine Gwo ^c   Lin, Wan Wan ^a,d  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

AMPK; Apoptosis; PDK; ROS; Starvation; Warburg effect

Indexed keywords

GLUCOSE; LACTATE DEHYDROGENASE; LACTIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PYRUVATE DEHYDROGENASE KINASE; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CANCER CELL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE TRANSPORT; GLYCOLYSIS; HELA CELL; HUMAN; HUMAN CELL; NUTRITIONAL DEFICIENCY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL;

ADENOSINE TRIPHOSPHATE; AMP-ACTIVATED PROTEIN KINASES; APOPTOSIS; ENERGY METABOLISM; FOOD DEPRIVATION; GLYCOLYSIS; HELA CELLS; HUMANS; ISOTONIC SOLUTIONS; LACTIC ACID; MUTATION; NEOPLASMS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PYRUVIC ACID; REACTIVE OXYGEN SPECIES; TRANSCRIPTIONAL ACTIVATION;

EID: 84874547293     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2013.01.025     Document Type: Article

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