Losartan increases muscle insulin delivery and rescues insulin's metabolic action during lipid infusion via microvascular recruitment

American Journal of Physiology - Endocrinology and Metabolism

Volumn 304, Issue 5, 2013, Pages

  Wang, Nasui ^a,b   Chai, Weidong ^a   Zhao, Lina ^a   Tao, Lijian ^b   Cao, Wenhong ^c   Liu, Zhenqi ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c University of North Carolina   (United States)

Author keywords

Angiotensin receptors; Insulin action; Insulin uptake; Microvascular blood volume; Muscle

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; GLUCOSE; INSULIN; IODINE 125; LOSARTAN; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VOLUME; CONTROLLED STUDY; ENDOTHELIUM CELL; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; MUSCLE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BLOOD PRESSURE; CAPILLARIES; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME INHIBITORS; HYPOGLYCEMIC AGENTS; INSULIN; LIPIDS; LOSARTAN; MALE; MAP KINASE SIGNALING SYSTEM; MICROCIRCULATION; MUSCLE, SKELETAL; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84874512697     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00537.2012     Document Type: Article

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