메뉴 건너뛰기




Volumn 145, Issue 3, 2004, Pages 1161-1166

Glucocorticoids Differentially Modulate Insulin-Mediated Protein and Glycogen Synthetic Signaling Downstream of Protein Kinase B in Rat Myocardium

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DEXAMETHASONE; GLUCOCORTICOID; GLYCOGEN; GLYCOGEN SYNTHASE KINASE 3; INITIATION FACTOR 4E; INSULIN; PROTEIN KINASE B; S6 KINASE;

EID: 1442323681     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-1429     Document Type: Article
Times cited : (11)

References (43)
  • 2
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering BM, Coffer PJ 1995 Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376:599-602
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.1    Coffer, P.J.2
  • 3
    • 0032189381 scopus 로고    scopus 로고
    • Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
    • Coffer PJ, Jin J, Woodgett JR 1998 Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem J 335:1-13
    • (1998) Biochem J , vol.335 , pp. 1-13
    • Coffer, P.J.1    Jin, J.2    Woodgett, J.R.3
  • 4
    • 0032560521 scopus 로고    scopus 로고
    • Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway
    • Scott PH, Brunn GJ, Kohn AD, Roth RA, Lawrence Jr JC 1998 Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway. Proc Natl Acad Sci USA 95:7772-7777
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7772-7777
    • Scott, P.H.1    Brunn, G.J.2    Kohn, A.D.3    Roth, R.A.4    Lawrence Jr., J.C.5
  • 5
    • 0030883848 scopus 로고    scopus 로고
    • PHAS/4E-BPs as regulators of mRNA translation and cell proliferation
    • Lawrence JC, Abraham RT 1997 PHAS/4E-BPs as regulators of mRNA translation and cell proliferation. Trends Biochem Sci 22:345-349
    • (1997) Trends Biochem Sci , vol.22 , pp. 345-349
    • Lawrence, J.C.1    Abraham, R.T.2
  • 6
    • 0029989622 scopus 로고    scopus 로고
    • Insulin and diabetes cause reciprocal changes in the association of eIF-4E and PHAS-I in rat skeletal muscle
    • Kimball SR, Jefferson LS, Fadden P, Haystead TAJ, Lawrence JC 1996 Insulin and diabetes cause reciprocal changes in the association of eIF-4E and PHAS-I in rat skeletal muscle. Am J Physiol 270:C705-C709
    • (1996) Am J Physiol , vol.270
    • Kimball, S.R.1    Jefferson, L.S.2    Fadden, P.3    Haystead, T.A.J.4    Lawrence, J.C.5
  • 9
    • 0032079873 scopus 로고    scopus 로고
    • Regulation of translation initiation factors by signal transduction
    • Kleijn M, Scheper GC, Voorma HO, Thomas AA 1998 Regulation of translation initiation factors by signal transduction. Eur J Biochem 253:531-544
    • (1998) Eur J Biochem , vol.253 , pp. 531-544
    • Kleijn, M.1    Scheper, G.C.2    Voorma, H.O.3    Thomas, A.A.4
  • 10
    • 0030984321 scopus 로고    scopus 로고
    • New insights into the role and mechanism of glycogen synthase activation by insulin
    • Lawrence Jr JC, Roach PJ 1997 New insights into the role and mechanism of glycogen synthase activation by insulin. Diabetes 46:541-547
    • (1997) Diabetes , vol.46 , pp. 541-547
    • Lawrence Jr., J.C.1    Roach, P.J.2
  • 11
    • 0030951346 scopus 로고    scopus 로고
    • Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue
    • Cross DA, Watt PW, Shaw M, van der Kaay J, Downes CP, Holder JC, Cohen P 1997 Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue. FEBS Lett 406:211-215
    • (1997) FEBS Lett , vol.406 , pp. 211-215
    • Cross, D.A.1    Watt, P.W.2    Shaw, M.3    Van Der Kaay, J.4    Downes, C.P.5    Holder, J.C.6    Cohen, P.7
  • 12
    • 0035477020 scopus 로고    scopus 로고
    • GSK3 takes centre stage more than 20 years after its discovery
    • Frame S, Cohen P 2001 GSK3 takes centre stage more than 20 years after its discovery. Biochem J 359:1-16
    • (2001) Biochem J , vol.359 , pp. 1-16
    • Frame, S.1    Cohen, P.2
  • 13
    • 0033609812 scopus 로고    scopus 로고
    • Insulin and exercise decrease glycogen synthase kinase-3 activity by different mechanisms in rat skeletal muscle
    • Markuns JF, Wojtaszewski JF, Goodyear LJ 1999 Insulin and exercise decrease glycogen synthase kinase-3 activity by different mechanisms in rat skeletal muscle. J Biol Chem 274:24896-24900
    • (1999) J Biol Chem , vol.274 , pp. 24896-24900
    • Markuns, J.F.1    Wojtaszewski, J.F.2    Goodyear, L.J.3
  • 14
    • 0027163954 scopus 로고
    • Glucocorticoid regulation of insulin receptor and substrate IRS-1 tyrosine phosphorylation in rat skeletal muscle in vivo
    • Giorgino F, Almahfouz A, Goodyear LJ, Smith RJ 1993 Glucocorticoid regulation of insulin receptor and substrate IRS-1 tyrosine phosphorylation in rat skeletal muscle in vivo. J Clin Invest 91:2020-2030
    • (1993) J Clin Invest , vol.91 , pp. 2020-2030
    • Giorgino, F.1    Almahfouz, A.2    Goodyear, L.J.3    Smith, R.J.4
  • 15
    • 0033974349 scopus 로고    scopus 로고
    • Acute attenuation of translation initiation and protein synthesis by glucocorticoids in skeletal muscle
    • Shah OJ, Kimball SR, Jefferson LS 2000 Acute attenuation of translation initiation and protein synthesis by glucocorticoids in skeletal muscle. Am J Physiol Endocrinol Metab 278:E76-E82
    • (2000) Am J Physiol Endocrinol Metab , vol.278
    • Shah, O.J.1    Kimball, S.R.2    Jefferson, L.S.3
  • 16
    • 0035005804 scopus 로고    scopus 로고
    • Dexamethasone inhibits the stimulation of muscle protein synthesis and PHAS-I and p70 S6-kinase phosphorylation
    • Long W, Wei L, Barrett EJ 2001 Dexamethasone inhibits the stimulation of muscle protein synthesis and PHAS-I and p70 S6-kinase phosphorylation. Am J Physiol 280:E570-575
    • (2001) Am J Physiol , vol.280
    • Long, W.1    Wei, L.2    Barrett, E.J.3
  • 17
    • 0032822890 scopus 로고    scopus 로고
    • Intracellular skeletal muscle glucose metabolism is differentially altered by dexamethasone treatment of normoglycemic relatives of type 2 diabetic patients
    • Henriksen JE, Alford F, Vaag A, Handberg A, Beck-Nielsen H 1999 Intracellular skeletal muscle glucose metabolism is differentially altered by dexamethasone treatment of normoglycemic relatives of type 2 diabetic patients. Metabolism 48:1128-1135
    • (1999) Metabolism , vol.48 , pp. 1128-1135
    • Henriksen, J.E.1    Alford, F.2    Vaag, A.3    Handberg, A.4    Beck-Nielsen, H.5
  • 18
    • 0014284796 scopus 로고
    • Influences of corticosteroids on cardiac glycogen concentration in the rat
    • Daw JC, Lefer AM, Berne RM 1968 Influences of corticosteroids on cardiac glycogen concentration in the rat. Circ Res 22:639-647
    • (1968) Circ Res , vol.22 , pp. 639-647
    • Daw, J.C.1    Lefer, A.M.2    Berne, R.M.3
  • 19
    • 0037225604 scopus 로고    scopus 로고
    • Adrenalectomy enhances the insulin sensitivity of muscle protein synthesis
    • Long W, Barrett EJ, Wei L, Liu Z 2003 Adrenalectomy enhances the insulin sensitivity of muscle protein synthesis. Am J Physiol Endocrinol Metab 284: E102-E109
    • (2003) Am J Physiol Endocrinol Metab , vol.284
    • Long, W.1    Barrett, E.J.2    Wei, L.3    Liu, Z.4
  • 20
    • 0029945963 scopus 로고    scopus 로고
    • Glucocorticoids and acidosis stimulate protein and amino acid catabolism in vivo
    • May RC, Bailey JL, Mitch WE, Masud T, England BK 1996 Glucocorticoids and acidosis stimulate protein and amino acid catabolism in vivo. Kidney Int 49:679-683
    • (1996) Kidney Int , vol.49 , pp. 679-683
    • May, R.C.1    Bailey, J.L.2    Mitch, W.E.3    Masud, T.4    England, B.K.5
  • 21
    • 0015753387 scopus 로고
    • Corticosteroid feedback control of ACTH secretion: Effect of stress-induced corticosterone secretion on subsequent stress responses in the rat
    • Dallman MF, Jones MT 1973 Corticosteroid feedback control of ACTH secretion: effect of stress-induced corticosterone secretion on subsequent stress responses in the rat. Endocrinology 92:1367-1375
    • (1973) Endocrinology , vol.92 , pp. 1367-1375
    • Dallman, M.F.1    Jones, M.T.2
  • 22
    • 0018520840 scopus 로고
    • Glucose clamp technique, a method for quantifying insulin secretion and resistance
    • DeFronzo RA, Tobin JD, Andres R 1979 Glucose clamp technique, a method for quantifying insulin secretion and resistance. Am J Physiol 237:E214-E223
    • (1979) Am J Physiol , vol.237
    • DeFronzo, R.A.1    Tobin, J.D.2    Andres, R.3
  • 23
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.1
  • 24
    • 0030934285 scopus 로고    scopus 로고
    • Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes
    • Fadden P, Haystead TAJ, Lawrence JC 1997 Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes. J Biol Chem 272:10240-10247
    • (1997) J Biol Chem , vol.272 , pp. 10240-10247
    • Fadden, P.1    Haystead, T.A.J.2    Lawrence, J.C.3
  • 25
    • 0028034233 scopus 로고
    • Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5′-cap function
    • Pause A, Belsham G, Gingras AC, Donze O, Lin TA, Lawrence JC, Sonenberg N 1994 Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5′-cap function. Nature 371:762-767
    • (1994) Nature , vol.371 , pp. 762-767
    • Pause, A.1    Belsham, G.2    Gingras, A.C.3    Donze, O.4    Lin, T.A.5    Lawrence, J.C.6    Sonenberg, N.7
  • 26
    • 0034057277 scopus 로고    scopus 로고
    • Multiple mechanisms control phosphorylation of PHAS-I in five (S/T) sites that govern translational repression
    • Mothe-Satney I, Yang D, Fadden P, Haystead TAJ, Lawrence Jr JC 2000 Multiple mechanisms control phosphorylation of PHAS-I in five (S/T) sites that govern translational repression. Mol Cell Biol 20:3558-3567
    • (2000) Mol Cell Biol , vol.20 , pp. 3558-3567
    • Mothe-Satney, I.1    Yang, D.2    Fadden, P.3    Haystead, T.A.J.4    Lawrence Jr., J.C.5
  • 28
    • 0014428937 scopus 로고
    • A rapid filter paper assay for UDP glucose-glycogen glucosyltransferase, including an improved biosynthesis of UDP-14C-glucose
    • Thomas JA, Schlender KK, Larner J 1968 A rapid filter paper assay for UDP glucose-glycogen glucosyltransferase, including an improved biosynthesis of UDP-14C-glucose. Anal Biochem 25:486-499
    • (1968) Anal Biochem , vol.25 , pp. 486-499
    • Thomas, J.A.1    Schlender, K.K.2    Larner, J.3
  • 29
    • 0017159024 scopus 로고
    • A rapid method for the determination of glycogen content and radioactivity in small quantities of tissue or isolated hepatocytes
    • Chan TM, Exton JH 1976 A rapid method for the determination of glycogen content and radioactivity in small quantities of tissue or isolated hepatocytes. Anal Biochem 71:96-105
    • (1976) Anal Biochem , vol.71 , pp. 96-105
    • Chan, T.M.1    Exton, J.H.2
  • 30
    • 0034704134 scopus 로고    scopus 로고
    • Expression of constitutively active phosphatidylinositol 3-kinase inhibits activation of caspase 3 and apoptosis of cardiac muscle cells
    • Wu W, Lee W-L, Wu YY, Chen D, Liu T-J, Jang A, Sharma PM, Wang PH 2000 Expression of constitutively active phosphatidylinositol 3-kinase inhibits activation of caspase 3 and apoptosis of cardiac muscle cells. J Biol Chem 275: 40113-40119
    • (2000) J Biol Chem , vol.275 , pp. 40113-40119
    • Wu, W.1    Lee, W.-L.2    Wu, Y.Y.3    Chen, D.4    Liu, T.-J.5    Jang, A.6    Sharma, P.M.7    Wang, P.H.8
  • 31
    • 0028008197 scopus 로고
    • Effect of insulin on rat heart and skeletal muscle phenylalanyl-tRNA labeling and protein synthesis in vivo
    • Young LH, Stirewalt W, McNulty PH, Revkin JH, Barrett EJ 1994 Effect of insulin on rat heart and skeletal muscle phenylalanyl-tRNA labeling and protein synthesis in vivo. Am J Physiol 267:E337-E342
    • (1994) Am J Physiol , vol.267
    • Young, L.H.1    Stirewalt, W.2    McNulty, P.H.3    Revkin, J.H.4    Barrett, E.J.5
  • 32
    • 0027288716 scopus 로고
    • Response of rat heart and skeletal muscle protein in vivo to insulin and amino acid infusion
    • McNulty PH, Young LH, Barrett EJ 1993 Response of rat heart and skeletal muscle protein in vivo to insulin and amino acid infusion. Am J Physiol 264:E958-E965
    • (1993) Am J Physiol , vol.264
    • McNulty, P.H.1    Young, L.H.2    Barrett, E.J.3
  • 34
    • 0016769461 scopus 로고
    • RNA content in the heart muscle cells following adrenalectomy and additional overload in the rat
    • Suzuki T 1975 RNA content in the heart muscle cells following adrenalectomy and additional overload in the rat. Tohoku J Exp Med 115:239-225
    • (1975) Tohoku J Exp Med , vol.115 , pp. 239-1225
    • Suzuki, T.1
  • 35
    • 0020711112 scopus 로고
    • Role of adrenals on development of pressure-induced myocardial hypertrophy
    • Nichols JR, Clancy RL, Gonzalez NC 1983 Role of adrenals on development of pressure-induced myocardial hypertrophy. Am J Physiol 244:H234-H238
    • (1983) Am J Physiol , vol.244
    • Nichols, J.R.1    Clancy, R.L.2    Gonzalez, N.C.3
  • 36
    • 0021487079 scopus 로고
    • Effects of adrenalectomy on activation of glycogen phosphorylase in rat myocardium
    • Reese JB, Mayer SE, Brunton LL 1984 Effects of adrenalectomy on activation of glycogen phosphorylase in rat myocardium. Am J Physiol 247:E389-E397
    • (1984) Am J Physiol , vol.247
    • Reese, J.B.1    Mayer, S.E.2    Brunton, L.L.3
  • 37
    • 0021219884 scopus 로고
    • Effects of dexamethasone administration on hepatic glycogen synthesis and accumulation in adrenalectomized fasted rats
    • Margolis R, Curnow R 1984 Effects of dexamethasone administration on hepatic glycogen synthesis and accumulation in adrenalectomized fasted rats. Endocrinology 115:625-629
    • (1984) Endocrinology , vol.115 , pp. 625-629
    • Margolis, R.1    Curnow, R.2
  • 38
    • 17344381333 scopus 로고
    • Modulation by adrenalectomy and fasting of insulin effects in perfused hindlimb muscle
    • Shikama H, Chu DT, Exton JH 1982 Modulation by adrenalectomy and fasting of insulin effects in perfused hindlimb muscle. Am J Physiol 242:E323-E329
    • (1982) Am J Physiol , vol.242
    • Shikama, H.1    Chu, D.T.2    Exton, J.H.3
  • 39
    • 0015514917 scopus 로고
    • Effect of insulin on glycogen synthesis and synthetase enzyme activity in the perfused rat heart
    • Adolfsson S, Isaksson O, Hjalmarson A 1972 Effect of insulin on glycogen synthesis and synthetase enzyme activity in the perfused rat heart. Biochim Biophys Acta 279:146-156
    • (1972) Biochim Biophys Acta , vol.279 , pp. 146-156
    • Adolfsson, S.1    Isaksson, O.2    Hjalmarson, A.3
  • 40
    • 0014182855 scopus 로고
    • Effect of sympathectomy on cardiac UDPG-glycogen transferase activity in the cat
    • Daw JC, Berne RM 1967 Effect of sympathectomy on cardiac UDPG-glycogen transferase activity in the cat. Am J Physiol 213:1480-1484
    • (1967) Am J Physiol , vol.213 , pp. 1480-1484
    • Daw, J.C.1    Berne, R.M.2
  • 41
    • 0014495289 scopus 로고
    • UDP glucose: α-1, 4-glucan α-4-glucosyltransferase in heart regulation of the activity of the transferase in vivo and in vitro in rat a dissociation in the action of insulin on transport and on transferase conversion
    • Huijing F, Nuttall FQ, Villar-Palasi C, Larner J 1969 UDP glucose: α-1, 4-glucan α-4-glucosyltransferase in heart regulation of the activity of the transferase in vivo and in vitro in rat A dissociation in the action of insulin on transport and on transferase conversion. Biochim Biophys Acta 177:204-212
    • (1969) Biochim Biophys Acta , vol.177 , pp. 204-212
    • Huijing, F.1    Nuttall, F.Q.2    Villar-Palasi, C.3    Larner, J.4
  • 43
    • 0028814010 scopus 로고
    • Transient ischemia induces regional myocardial glycogen synthase activation and glycogen synthesis in vivo
    • McNulty PH, Luba MC 1995 Transient ischemia induces regional myocardial glycogen synthase activation and glycogen synthesis in vivo. Am J Physiol 268:H364-H370
    • (1995) Am J Physiol , vol.268
    • McNulty, P.H.1    Luba, M.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.