Contribution of mature hepatocytes to small hepatocyte-like progenitor cells in retrorsine-exposed rats with chimeric livers

Hepatology

Volumn 57, Issue 3, 2013, Pages 1215-1224

  Chen, Ya Hui ^a   Chang, Mei Hwei ^a   Chien, Chin Sung ^a   Wu, Shang Hsin ^a   Yu, Chun Hsien ^b   Chen, Hui Ling ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b TZU CHI UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

4,4' METHYLENEDIANILINE; CCAAT ENHANCER BINDING PROTEIN ALPHA; DIPEPTIDYL PEPTIDASE IV; EPITHELIAL CELL ADHESION MOLECULE; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE 6 PHOSPHATASE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; LAMININ; RETRORSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LINEAGE; CELL MATURATION; CELL PROLIFERATION; CHIMERA; CONTROLLED STUDY; CYTOPLASM; HEPATOCYTE TRANSPLANTATION; IMMUNOFLUORESCENCE TEST; LIVER; LIVER CELL; MALE; NONHUMAN; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMALL HEPATOCYTE LIKE PROGENITOR CELL; STEM CELL;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINEAGE; CELL SIZE; DIPEPTIDYL PEPTIDASE 4; FEMALE; HEPATECTOMY; HEPATOCYTES; MALE; PHENYLALANINE; PYRROLIZIDINE ALKALOIDS; RATS; RATS, INBRED F344; STEM CELLS; TRANSPLANTATION CHIMERA;

EID: 84874497610     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26104     Document Type: Article

References (43)

1. Michalopoulous GK, DeFrances MC. Liver regeneration. Science 1997; 276: 60-66.
2. Fausto N, Campell JS, Riehle KJ. Liver regeneration. HEPATOLOGY 2006; 43(Suppl 1): S45-S53.
3. Sell S. Heterogeneity and plasticity of hepatocyte lineage cells. HEPATOLOGY 2001; 33: 738-750.
4. Fausto N, Campbell JS. The role of hepatocytes and oval cells in liver regeneration and repopulation. Mech Dev 2003; 120: 117-130.
5. Fausto N. Liver regeneration and repair: hepatocytes, progenitor cells, and stem cells. HEPATOLOGY 2004; 39: 1477-1487.
6. Lemire JM, Shiojiri N, Fausto, N. Oval cell proliferation and the origin of small hepatocytes in liver injury induced by D-galactosamine. Am J Pathol 1991; 139: 535-552.
7. Dabeva MD, Shafritz DA. Activation, proliferation, and differentiation of progenitor cells into hepatocytes in the D-galactosamine model of liver regeneration. Am J Pathol 1993; 143: 1606-1620.
8. Factor VM, Radaeva SA, Thorgeirsson SS. Origin and fate of oval cells in dipin-induced hepatocarcinogenesis in the mouse. Am J Pathol 1994; 145: 409-422.
9. Kuwahara R, Kofman AV, Landis CS, Swenson ES, Barendswaard E, Theise ND. The hepatic stem cell niche: identification by label-retaining cell assay. HEPATOLOGY 2008; 47: 1994-2002.
10. Gordon GJ, Coleman WB, Grisham JW. Liver regeneration in rats with retrorsine-induced hepatocellular injury proceeds through a novel cellular response. Am J Pathol 2000; 156: 607-619.
11. Best DH, Coleman WB. Bile duct destruction by 4, 4′-diaminodiphenylmethane does not block the small hepatocyte-like progenitor cell response in retrorsine-exposed rats. HEPATOLOGY 2007; 46: 1611-1619.
12. Braun KM, Sandgren EP. Cellular origin of regenerating parenchyma in a mouse model of severe hepatic injury. Am J Pathol 2000; 57: 561-569.
13. Vig P, Russo FP, Edwards RJ, Tadrous PJ, Wright NA, Thomas HC, et al. The sources of parenchymal regeneration after chronic hepatocellular liver injury in mice. HEPATOLOGY 2006; 43: 316-324.
14. Avril A, Pichard V, Bralet MP, Ferry N. Mature hepatocytes are the source of small hepatocyte-like progenitor cells in the retrorsine model of liver injury. J Hepatol 2004; 41: 737-743.
15. Pichard V, Aubert D, Ferry N. Direct in vivo cell lineage analysis in the retrorsine and 2AAF models of liver injury after genetic labeling in adult and newborn rats. PLoS ONE 2009; 4: e7267.
16. Coleman WB, Best DH. Cellular responses in experimental liver injury: possible cellular origins of regenerative stem-like progenitor cells. HEPATOLOGY 2005; 41: 1173-1176.
17. Best DH, Coleman WB. Cells of origin of small hepatocyte-like progenitor cells in the retrorsine model of rat liver injury and regeneration. HEPATOLOGY 2008; 48: 369-371.
18. Yu CH, Chen HL, Chen YH, Chien CS, Chang MF, Chang MH. Impaired hepatocyte regeneration in acute severe hepatic injury enhances effective repopulation by transplanted hepatocytes. Cell Transplant 2009; 18: 1081-1092.
19. Rajvanshi P, Kerr A, Bhargava KK, Burk RD, Gupta S. Studies of liver repopulation using the dipeptidyl peptidase IV deficient rats. HEPATOLOGY 1996; 23: 482-496.
20. Yu CH, Chang MH, Chen YH, Chang MF, Chien CS, Chen HL. Hepatocyte transplantation and the differentiation fate of host oval cells in acute severe hepatic injury. Cell Transplant 2010; 19: 231-243.
21. Rutenburg AM, Kim H, Fischbein JW, Hanker JS, Wassekrug HL, Seligman AM. Histochemical and ultrastructural demonstration of gamma-glutamyl transpeptidase activity. Histochem Cytochem 1969; 17: 517-526.
22. Paku S, Nagy P, Kopper L, Thorgeirsson SS. 2-Acetylaminofluorene dose-dependent differentiation of rat oval cells into hepatocytes: confocal and electron microscopic studies. HEPATOLOGY 2004; 39: 1353-1361.
23. Lorenzini S, Bird TG, Boulter L, Bellamy C, Samuel K, Aucott R, et al. Characterisation of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver. Gut 2010; 59: 645-654.
24. Zhang L, Theise N, Chua M, Reid LM. The stem cell niche of human livers: symmetry between development and regeneration. HEPATOLOGY 2008; 48: 1598-1607.
25. Yoon SM, Gerasimidou D, Kuwahara R, Hyuroglou P, Yoon JE, Park YN, et al. Epithelial cell adhesion molecule (EpCAM) marks hepatocytes newly derived from stem/progenitor cells in humans. HEPATOLOGY 2011; 53: 964-973.
26. Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, et al. Morphogenetic competence of HNF4-alpha deficient mouse hepatic cells. J Hepatol 2008; 49: 384-395.
27. Petersen BE, Zajac VF, Michalopoulos GK. Bile duct damage induced by methylene dianiline inhibits oval cell activation. Am J Pathol 1997; 151: 905-909.
28. Dabeva MD, Laconi E, Oren R, Petkov PM, Hurston E, Shafritz DA. Liver regeneration and alpha-fetoprotein messenger RNA expression in the retrorsine model for hepatocyte transplantation. Cancer Res 1998; 58: 5825-5834.
29. Michalopoulos GK, Barus L, Bowen WC. Transdifferentiation of rat hepatocytes into biliary cells after bile duct ligation and toxic biliary injury. HEPATOLOGY 2005; 41: 535-544.
30. Chen Y, Wong PP, Sjeklocha L, Steer CJ, Sahin MB. Mature hepatocytes exhibit unexpected plasticity by direct dedifferentiation into liver progenitor cells in culture. HEPATOLOGY 2012; 55: 563-574.
31. Chu AS, Diaz R, Hui JJ, Yanger K, Zong Y, Alpini G, et al. Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis. HEPATOLOGY 2011; 53: 1685-1695.
32. Malato Y, Naqvi S, Schurmann N, Ng R, Wang B, Zape J, et al. Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration. J Clin Invest 2011; 121: 4850-4860.
33. Bhave VS, Paranjpe S, Bowen WC, Donthamsetty S, Bell AW, Khillan JS, et al. Genes inducing iPS phenotype play a role in hepatocyte survival and proliferation in vitro and liver regeneration in vivo. HEPATOLOGY 2011; 54: 1360-1370.
34. Zhou Q, Melton DA. Extreme makeover: converting one cell into another. Cell Stem Cell 2008; 3: 382-388.
35. Alpini G, Phillips JO, Vroman B, LaRusso NF. Recent advances in the isolation of liver cells. HEPATOLOGY 1994; 20: 494-514.
36. Yovchev MI, Grozdanov PN, Zhao H, Racherla H, Guha C, Dabeva MD. Identification of adult hepatic progenitor cells capable of repopulating injured rat liver. HEPATOLOGY 2008; 47: 636-647.
37. Chojkier M. Hepatic sinusoidal obstruction syndrome: toxicity of pyrrolizidine alkaloids. J Hepatol 2003; 39: 437-446.
38. Gordon GJ, Coleman WB, Grisham JW. Induction of cytochrome P450 enzymes in the livers of rats treated with the pyrrolizidine alkaloid retrorsine. Exp Mol Pathol 2000; 69: 17-26.
39. Laconi E, Oren R, Mukhopadhyay DK, Hurston E, Laconi S, Pani P, et al. Long term, near total liver replacement by transplantation of hepatocytes in rats treated with retrorsine. Am J Pathol 1998; 158: 319-329.
40. Koenig S, Aurich H, Schneider C, Krause P, Haftendorn R, Becker H, et al. Zonal expression of hepatocytic marker enzymes during liver repopulation. Histochem Cell Biol 2007; 128: 105-114.
41. Wu YM, Joseph B, Berishvili E, Kumaran V, Gupta S. Hepatocyte transplantation and drug-induced perturbations in liver cell compartments. HEPATOLOGY 2008; 47: 279-287.
42. Alison M, Golding M, Lalani EN, Nagy P, Thorgeirsson S, Sarraf C. Wholesale hepatocytic differentiation in the rat from ductular oval cells, the progeny of biliary stem cells. J Hepatol 1997; 26: 343-352.
43. Turner R, Lozoya O, Wang Y, Cardinale V, Gaudio E, Alpini G, et al. Human hepatic stem cell and maturational liver lineage biology. HEPATOLOGY 2011; 53: 1035-1045.