Cells of origin of small hepatocyte-like progenitor cells in the retrorsine model of rat liver injury and regeneration

Journal of Hepatology

Volumn 48, Issue 2, 2008, Pages 369-371

  Hunter Best, D ^a   Coleman, William B ^b  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; RETRORSINE;

CELL LINEAGE; CELL PROLIFERATION; CELL TYPE; CYTOLOGY; LETTER; LIVER CARCINOGENESIS; LIVER CELL; LIVER INJURY; LIVER REGENERATION; NONHUMAN; OVAL CELL; PHENOTYPE; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; SMALL HEPATOCYTE LIKE PROGENITOR CELL; STEM CELL;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; HEPATOCYTES; LIVER REGENERATION; PYRROLIZIDINE ALKALOIDS; RATS; STEM CELLS;

EID: 38049009566     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2007.11.002     Document Type: Letter

References (13)

1. Laconi E., Oren R., Mukhopadhyay D.K., Hurston E., Laconi S., Pani P., et al. Long-term, near-total liver replacement by transplantation of isolated hepatocytes in rats treated with retrorsine. Am J Pathol 153 (1998) 319-329
2. Gordon G.J., Coleman W.B., Hixson D.C., and Grisham J.W. Liver regeneration in rats with retrorsine-induced hepatocellular injury proceeds through a novel cellular response. Am J Pathol 156 (2000) 607-619
3. Coleman W.B., and Best D.H. Cellular responses in experimental liver injury: possible cellular origins of regenerative stem-like progenitor cells. Hepatology 41 (2005) 1173-1176
4. Ferry N., Duplessis O., Houssin D., Danos O., and Heard J.M. Retroviral-mediated gene transfer into hepatocytes in vivo. Proc Natl Acad Sci USA 88 (1991) 8377-8381
5. Branchereau S., Calise D., and Ferry N. Factors influencing retroviral-mediated gene transfer into hepatocytes in vivo. Hum Gene Ther 5 (1994) 803-808
6. Bralet M.P., Branchereau S., Brechot C., and Ferry N. Cell lineage study in the liver using retroviral mediated gene transfer. Evidence against the streaming of hepatocytes in normal liver. Am J Pathol 144 (1994) 896-905
7. Bralet M.P., Calise D., Brechot C., and Ferry N. In vivo cell lineage analysis during chemical hepatocarcinogenesis using retroviral-mediated gene transfer. Lab Invest 74 (1996) 871-881
8. Gournay J., Auvigne I., Pichard V., Ligeza C., Bralet M.P., and Ferry N. In vivo cell lineage analysis during chemical hepatocarcinogenesis in rats using retroviral-mediated gene transfer: evidence for dedifferentiation of mature hepatocytes. Lab Invest 82 (2002) 781-788
9. Avril A., Pichard V., Bralet M.P., and Ferry N. Mature hepatocytes are the source of small hepatocyte-like progenitor cells in the retrorsine model of liver injury. J Hepatol 41 (2004) 737-743
10. Best D.H., and Coleman W.B. Treatment with 2-AAF blocks the small hepatocyte-like progenitor cell response in retrorsine-exposed rats. J Hepatol 46 (2007) 1055-1063
11. Best D.H., and Coleman W.B. Bile duct destruction by 4,4′-diaminodiphenylmethane does not block the small hepatocyte-like progenitor cell response in retrorsine-exposed rats. Hepatology 46 (2007) 1611-1619
12. Gordon G.J., Coleman W.B., and Grisham J.W. Temporal analysis of hepatocyte differentiation by small hepatocyte-like progenitor cells during liver regeneration in retrorsine-exposed rats. Am J Pathol 157 (2000) 771-786
13. Gordon G.J., Coleman W.B., and Grisham J.W. Induction of cytochrome P450 enzymes in the livers of rats treated with the pyrrolizidine alkaloid retrorsine. Exp Mol Pathol 69 (2000) 17-26