Doseresponse relationship, acute toxicity, and therapeutic index between the alkaloid extract of mitragyna speciosa and its main active compound mitragynine in mice

Drug Development Research

Volumn 74, Issue 1, 2013, Pages 23-30

  Sabetghadam, Azadeh ^a   Navaratnam, Visweswaran ^a   Mansor, Sharif Mahsufi ^a  

^a SCHOOL OF PHYSICS   (Malaysia)

Author keywords

LD50; Mitragyna speciosa; mitragynine; safety; therapeutic index

Indexed keywords

MITRAGYNA SPECIOSA EXTRACT; MITRAGYNINE; MORPHINE SULFATE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ARTICLE; CONTROLLED STUDY; COSMETIC INDUSTRY; DOSE RESPONSE; DRUG POTENCY; DRUG SAFETY; LD 50; MALE; MOUSE; NONHUMAN; PLANT LEAF; SINGLE DRUG DOSE; TOXICITY TESTING;

EID: 84874489561     PISSN: 02724391     EISSN: 10982299     Source Type: Journal    
DOI: 10.1002/ddr.21052     Document Type: Article

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