Mitragynine attenuates withdrawal syndrome in morphine-withdrawn zebrafish

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Khor, Beng Siang ^a   Jamil, Mohd Fadzly ^a   Adenan, Mohamad Ilham ^a,b   Shu Chien, Alexander Chong ^a,c  

^a Environment and Climate Change   (Malaysia)

^b FOREST RESEARCH INSTITUTE MALAYSIA   (Malaysia)

^c SCHOOL OF PHYSICS   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2; HYDROCORTISONE; MESSENGER RNA; MITRAGYNINE; MORPHINE; PRODYNORPHIN; CORTICOTROPIN RELEASING FACTOR RECEPTOR; CRF RECEPTOR TYPE 2; ENKEPHALIN; PREPROENKEPHALIN; PROTEIN PRECURSOR; RAUWOLFIA ALKALOID;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ENZYME INHIBITION; EXPLORATORY BEHAVIOR; FEMALE; GENE SEQUENCE; MALE; MORPHINE ADDICTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPIATE ADDICTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; STRESS; SWIMMING; TREATMENT RESPONSE; WITHDRAWAL SYNDROME; ZEBRA FISH; ANIMAL; BEHAVIOR; BIOSYNTHESIS; CONDITIONING; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PSYCHOLOGICAL ASPECT;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; CONDITIONING (PSYCHOLOGY); ENKEPHALINS; FEMALE; GENE EXPRESSION REGULATION; HYDROCORTISONE; MALE; MORPHINE; PROTEIN PRECURSORS; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; RNA, MESSENGER; SECOLOGANIN TRYPTAMINE ALKALOIDS; SPATIAL BEHAVIOR; SUBSTANCE WITHDRAWAL SYNDROME; SWIMMING; ZEBRAFISH;

EID: 83755229292     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028340     Document Type: Article

References (55)

1. Koob GF, (2008) A role for brain stress systems in addiction. Neuron 59: 11-34.
2. Koob GF, Caine SB, Parsons L, Markou A, Weiss F, (1997) Opponent process model and psychostimulant addiction. Pharmacology Biochemistry and Behavior 57: 513-521.
3. Barr AM, Boyda HN, Procyshyn RM, (2011) Withdrawal. In: Olmstead MC, editors. Animal model of drug addiction. Neuromethods, Vol 53 New York, NY Springer Sciences.
4. Kosten TR, O'Connor PG, (2003) Management of drug and alcohol withdrawal. New England Journal of Medicine 348: 1786-1795.
5. Kreek MJ, LaForge KS, Butelman E, (2002) Pharmacotherapy of addictions. Nature Review Drug Discovery 1: 710-726.
6. Prisinzano TE, (2008) Natural products as tools for neuroscience: discovery and development of novel agents to treat drug abuse. Journal of Natural Products 72: 581-587.
7. Shi J, Liu Y-L, Fang Y-X, Xu G-Z, Zhai H-F, et al. (2006) Traditional Chinese medicine in treatment of opiate addiction. Acta Pharmacol Sin 27: 1303-1308.
8. Liu T-t, Shi J, Epstein D, Bao Y-P, Lu L, (2009) A meta-analysis of Chinese herbal medicine in treatment of managed withdrawal from heroin. Cellular and Molecular Neurobiology 29: 17-25.
9. Jansen KLR, Prast CJ, (1988) Ethnopharmacology of kratom and the Mitragyna alkaloids. Journal of Ethnopharmacology 23: 115-119.
10. Boyer EW, Babu KM, Adkins JE, McCurdy CR, Halpern JH, (2008) Self-treatment of opioid withdrawal using kratom (Mitragynia speciosa Korth). Addiction 103: 1048-1050.
11. McWhirter L, Morris S, (2010) A case report of inpatient detoxification after Kratom Mitragyna speciosa dependence. European Addiction Research 16: 229-231.
12. Babu KM, McCurdy CR, Boyer EW, (2008) Opioid receptors and legal highs: Salvia divinorum and Kratom. Clinical Toxicology 46: 146-152.
13. Adkins JE, Boyer EW, McCurdy CR, (2011) Mitragyna speciosa, a psychoactive tree from Southeast Asia with opioid activity. Current Topics in Medicinal Chemistry 11: 1165-1175.
14. Matsumoto K, Mizowaki M, Suchitra T, Takayama H, Sakai S-i, et al. (1996) Antinociceptive action of mitragynine in mice: Evidence for the involvement of supraspinal opioid receptors. Life Sciences 59: 1149-1155.
15. Idayu NF, Hidayat MT, Moklas MA, Sharida F, Raudzah AR, et al. (2011) Antidepressant-like effect of mitragynine isolated from Mitragyna speciosa Korth in mice model of depression. Phytomedicine 18: 402-407.
16. Kumarnsit E, Keawpradub N, Nuankaew W, (2007) Effect of Mitragyna speciosa aqueous extract on ethanol withdrawal symptoms in mice. Fitoterapia 78: 182-185.
17. Cachat J, Canavello P, Elegante M, Bartels B, Hart P, et al. (2010) Modeling withdrawal syndrome in zebrafish. Behavioural Brain Research 208: 371-376.
18. Lau B, Bretaud S, Huang Y, Lin E, Guo S, (2006) Dissociation of food and opiate preference by a genetic mutation in zebrafish. Genes, Brain and Behavior 5: 497-505.
19. Ninkovic J, Bally-Cuif L, (2006) The zebrafish as a model system for assessing the reinforcing properties of drugs of abuse. Methods 39: 262-274.
20. Rink E, Wullimann MF, (2002) Development of the catecholaminergic system in the early zebrafish brain: an immunohistochemical study. Developmental Brain Research 137: 89-100.
21. Lopez-Patino MA, Yu L, Yamamoto BK, Zhdanova IV, (2008) Gender differences in zebrafish responses to cocaine withdrawal. Physiology & Behavior 95: 36-47.
22. Owens MJ, Nemeroff CB, (1991) Physiology and pharmacology of corticotropin-releasing factor. Pharmacological Reviews 43: 425-473.
23. Sarnyai Z, Biro E, Gardi J, Vecsernyes M, Julesz J, et al. (1995) Brain corticotropin-releasing factor mediates 'anxiety-like' behavior induced by cocaine withdrawal in rats. Brain Research 675: 89-97.
24. Perrin MH, Donaldson CJ, Chen R, Lewis KA, Vale WW, (1993) Cloning and functional expression of a rat brain corticotropin releasing factor (CRF) receptor. Endocrinology 133: 3058-3061.
25. Lovenberg TW, Liaw CW, Grigoriadis DE, Clevenger W, Chalmers DT, et al. (1995) Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain. Proceedings of the National Academy of Sciences 92: 836-840.
26. Iredale PA, Alvaro JD, Lee Y, Terwilliger R, Chen YL, et al. (2000) Role of corticotropin-releasing factor receptor-1 in opiate withdrawal. Journal of Neurochemistry 74: 199-208.
27. Navarro-Zaragoza J, Nunez C, Laorden ML, Milanes MV, (2010) Effects of corticotropin-releasing factor receptor-1 antagonists on the brain stress system responses to morphine withdrawal. Molecular Pharmacology 77: 864-873.
28. Contarino A, Papaleo F, (2005) The corticotropin-releasing factor receptor-1 pathway mediates the negative affective states of opiate withdrawal. Proceedings of the National Academy of Sciences of the United States of America 102: 18649-18654.
29. Papaleo F, Ghozland S, Ingallinesi M, Roberts AJ, Koob GF, et al. (2008) Disruption of the CRF2 receptor pathway decreases the somatic expression of opiate withdrawal. Neuropsychopharmacology 33: 2878-2887.
30. Bruchas MR, Land BB, Chavkin C, (2010) The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors. Brain Research 1314: 44-55.
31. Beardsley P, Howard J, Shelton K, Carroll F, (2005) Differential effects of the novel kappa opioid receptor antagonist, JDTic, on reinstatement of cocaine-seeking induced by footshock stressors vs cocaine primes and its antidepressant-like effects in rats. Psychopharmacology 183: 118-126.
32. Land BB, Bruchas MR, Lemos JC, Xu M, Melief EJ, et al. (2008) The dysphoric component of stress is encoded by activation of the dynorphin κ-opioid system. The Journal of Neuroscience 28: 407-414.
33. Bruchas MR, Land BB, Lemos JC, Chavkin C, (2009) CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior. PLoS ONE 4: e8528.
34. Westerfield M, (1994) The Zebrafish Book: A Guide for the Laboratory Use of the Zebrafish (Danio rerio) Eugene, OR University of Oregon Press.
35. Mathur P, Lau B, Guo S, (2011) Conditioned place preference behavior in zebrafish. Nature Protocols 6: 338-345.
36. Cachat J, Stewart A, Grossman L, Gaikwad S, Kadri F, et al. (2010) Measuring behavioral and endocrine responses to novelty stress in adult zebrafish. Nature Protocols 5: 1786-1799.
37. Utar Z, Majid MIA, Adenan MI, Jamil MFA, Lan TM, (2011) Mitragynine inhibits the COX-2 mRNA expression and prostaglandin E2 production induced by lipopolysaccharide in RAW264.7 macrophage cells. Journal of Ethnopharmacology 136: 75-82.
38. Lopez-Patino MA, Yu L, Cabral H, Zhdanova IV, (2008) Anxiogenic effects of cocaine withdrawal in zebrafish. Physiology & Behavior 93: 160-171.
39. Stewart A, Wong K, Cachat J, Gaikwad S, Kyzar E, et al. (2011) Zebrafish models to study drug abuse-related phenotypes. Reviews in the Neurosciences 22: 95-105.
40. Parmar A, Parmar M, Brennan CH, (2011) Zebrafish conditioned place preference models of drug reinforcement and relapse to drug seeking. In: Kalueff AV, Cachat J, editors. Zebrafish Neurobehavioral Protocols New York, NY Humana Press pp. 75-84.
41. Wendelaar Bonga SE, (1997) The stress response in fish. Physiological Reviews 77: 591-625.
42. Ramsay JM, Feist GW, Varga ZM, Westerfield M, Kent ML, et al. (2006) Whole-body cortisol is an indicator of crowding stress in adult zebrafish, Danio rerio. Aquaculture 258: 565-574.
43. Mommsen TP, Vijayan MM, Moon TW, (1999) Cortisol in teleosts: dynamics, mechanisms of action, and metabolic regulation. Reviews in Fish Biology and Fisheries 9: 211-268.
44. Bearn J, Buntwal N, Papadopoulos A, Checkley S, (2001) Salivary cortisol during opiate dependence and withdrawal. Addiction Biology 6: 157-162.
45. Li S-x, Li J, Epstein DH, Zhang XY, Kosten TR, et al. (2008) Serum cortisol secretion during heroin abstinence is elevated only nocturnally. The American Journal of Drug and Alcohol Abuse 34: 321-328.
46. Flik G, Klaren PHM, Van den Burg EH, Metz JR, Huising MO, (2006) CRF and stress in fish. General and Comparative Endocrinology 146: 36-44.
47. Chandrasekar G, Lauter G, Hauptmann G, (2007) Distribution of corticotropin-releasing hormone in the developing zebrafish brain. The Journal of Comparative Neurology 505: 337-351.
48. Pozzoli G, Bilezikjian LM, Perrin MH, Blount AL, Vale WW, (1996) Corticotropin-releasing factor (CRF) and glucocorticoids modulate the expression of type 1 CRF receptor messenger ribonucleic acid in rat anterior pituitary cell cultures. Endocrinology 137: 65-71.
49. Iredale PA, Terwilliger R, Widnell KL, Nestler EJ, Duman RS, (1996) Differential regulation of corticotropin-releasing factor 1 receptor expression by stress and agonist treatments in brain and cultured cells. Molecular Pharmacology 50: 1103-1110.
50. Nestler EJ, Aghajanian GK, (1997) Molecular and cellular basis of addiction. Science 278: 58-63.
51. Kasagi Y, Horiba N, Sakai K, Fukuda Y, Suda T, (2002) Involvement of cAMP-response element binding protein in corticotropin-releasing factor (CRF)-induced down-regulation of CRF Receptor 1 gene expression in rat anterior pituitary cells. Journal of Neuroendocrinology 14: 587-592.
52. Shaham Y, Erb S, Leung S, Buczek Y, Stewart J, (1998) CP-154,526, a selective, non-peptide antagonist of the corticotropin-releasing factor 1 receptor attenuates stress-induced relapse to drug seeking in cocaine- and heroin-trained rats. Psychopharmacology 137: 184-190.
53. Gonzalez-Nunez V, Marron Fernandez de Velasco E, Arsequell G, Valencia G, RodrÌguez RE, (2007) Identification of dynorphin A from zebrafish: A comparative study with mammalian dynorphin A. Neuroscience 144: 675-684.
54. McClung CA, Nestler EJ, Zachariou V, (2005) Regulation of gene expression by chronic morphine and morphine withdrawal in the locus ceruleus and ventral tegmental area. The Journal of Neuroscience 25: 6005-6015.
55. Hidayat MT, Apryani E, Nabishah B, Moklas MA, Sharida F, et al. (2010) Determination of mitragynine bound opioid receptors. Advances in Medical and Dental Sciences 3: 65-70.