Early pharmacotherapy with fluoxetine rescues dendritic pathology in the ts65dn mouse model of down syndrome

Brain Pathology

Volumn 23, Issue 2, 2013, Pages 129-143

  Guidi, Sandra ^a   Stagni, Fiorenza ^a   Bianchi, Patrizia ^a   Ciani, Elisabetta ^a   Ragazzi, Elena ^a   Trazzi, Stefania ^a   Grossi, Gabriele ^b   Mangano, Chiara ^a   Calzà, Laura ^a   Bartesaghi, Renata ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

antidepressants; dendritic development; Down syndrome; hippocampus; neuropathology; spine density

Indexed keywords

FLUOXETINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLINICAL PROTOCOL; COGNITIVE DEFECT; CONTROLLED STUDY; DENDRITIC PATHOLOGY; DENTATE GYRUS; DISEASE SEVERITY; DOWN SYNDROME; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INNERVATION; MENTAL DEFICIENCY; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEUROLOGIC DISEASE; NONHUMAN; PERINATAL PERIOD; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; CELL PROLIFERATION; DENDRITES; DENDRITIC SPINES; DISEASE MODELS, ANIMAL; DOWN SYNDROME; FLUOXETINE; HIPPOCAMPUS; MICE; NEUROGENESIS; NEURONS; SEROTONIN UPTAKE INHIBITORS;

EID: 84874457113     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2012.00624.x     Document Type: Article

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