Low-affinity B cells transport viral particles from the lung to the spleen to initiate antibody responses

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 50, 2012, Pages 20566-20571

  Bessa, Juliana ^a   Zabel, Franziska ^b   Link, Alexander ^a   Jegerlehner, Andrea ^a   Hinton, Heather J ^a   Schmitz, Nicole ^a,c   Bauer, Monika ^a   Kündig, Thomas M ^b   Saudan, Philippe ^a   Bachmann, Martin F ^b  

^a CYTOS BIOTECHNOLOGY AG   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c ACTELION PHARMACEUTICALS LTD   (Switzerland)

Author keywords

Trafficking; Vaccine

Indexed keywords

B LYMPHOCYTE RECEPTOR; COMPLEMENT RECEPTOR; COMPLEMENT RECEPTOR 2; FC RECEPTOR; GLYCOPROTEIN; IMMUNOGLOBULIN G; UNCLASSIFIED DRUG; COMPLEMENT COMPONENT C3D RECEPTOR; FCGR2B PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; VIRUS ANTIBODY; VIRUS ANTIGEN; VIRUS LIKE PARTICLE VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; BLOOD ANALYSIS; CELL INTERACTION; CELL TRANSPORT; CLINICAL ASSESSMENT; CONTROLLED STUDY; IMMUNE RESPONSE; LUNG MUCOSA; LYMPH FOLLICLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLENIC B CELL; VIRUS LIKE AGENT; ADOPTIVE TRANSFER; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; CELL MOTION; FEMALE; IMMUNOLOGY; INTRANASAL DRUG ADMINISTRATION; LUNG; SPLEEN; VIROLOGY;

ADMINISTRATION, INTRANASAL; ADOPTIVE TRANSFER; ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; B-LYMPHOCYTES; CELL MOVEMENT; FEMALE; IMMUNOGLOBULIN G; LUNG; MICE; MICE, INBRED C57BL; RECEPTORS, ANTIGEN, B-CELL; RECEPTORS, COMPLEMENT 3D; RECEPTORS, IGG; SPLEEN; VACCINES, VIRUS-LIKE PARTICLE;

EID: 84874433862     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1206970109     Document Type: Article

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