Impaired antibody response to group B streptococcal type III capsular polysaccharide in C3- and complement receptor 2-deficient mice

Journal of Immunology

Volumn 170, Issue 1, 2003, Pages 84-90

  Pozdnyakova, Olga ^a   Guttormsen, Hilde Kari ^c   Lalani, Farah N ^c   Carroll, Michael C ^a   Kasper, Dennis L ^b,c,d  

^a CENTER FOR BLOOD RESEARCH   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d CHANNING LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; BACTERIUM LIPOPOLYSACCHARIDE; COMPLEMENT COMPONENT C3 RECEPTOR; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT COMPONENT C3D RECEPTOR; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY;

ANIMAL CELL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ARTICLE; B LYMPHOCYTE; CELLULAR DISTRIBUTION; COMPLEMENT SYSTEM; CONTROLLED STUDY; DENDRITIC CELL; GERMINAL CENTER; HUMORAL IMMUNITY; MOUSE; NEWBORN INFECTION; NONHUMAN; PRIORITY JOURNAL; STREPTOCOCCUS AGALACTIAE; WILD TYPE;

EID: 0037220540     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.1.84     Document Type: Article

References (38)

1. Baker, C. J., M. A. Rench, M. S. Edwards, R. J. Carpenter, B. M. Hays, and D. L. Kasper. 1988. Immunization of pregnant women with a polysaccharide vaccine of group B Streptococcus. N. Engl. J. Med. 319:1180.
2. Timens, W., A. Boes, T. Rozeboom-Uiterwijk, and S. Poppema. 1989. Immaturity of the human splenic marginal zone in infancy: Possible contribution to the deficient infant immune response. J. Immunol. 143:3200.
3. van den Eertwegh, A. J., J. D. Laman, M. M. Schellekens, W. J. Boersma, and E. Claassen. 1992. Complement-mediated follicular localization of T-independent type-2 antigens: The role of marginal zone macrophages revisited. Eur. J. Immunol. 22:719.
4. Brown, A. R. 1992. Immunological functions of splenic B-lymphocytes. Crit. Rev. Immunol. 11:395.
5. Morse, H. C., 3rd, J. F. Kearney, P. G. Isaacson, M. Carroll, T. N. Fredrickson, and E. S. Jaffe. 2001. Cells of the marginal zone-origins, function and neoplasia. Leuk. Res. 25:169.
6. Lane, P. J., D. Gray, S. Oldfield, and I. C. MacLennan. 1986. Differences in the recruitment of virgin B cells into antibody responses to thymus-dependent and thymus-independent type-2 antigens. Eur. J. Immunol. 16:1569.
7. Timens, W. 1991. The human spleen and the immune system: Not just another lymphoid organ. Res. Immunol. 142:316.
8. Lee, C. J., S. D. Banks, and J. P. Li. 1991. Virulence, immunity, and vaccine related to Streptococcus pneumoniae. Crit. Rev. Microbiol. 18:89.
9. Rickert, R. C., K. Rajewsky, and J. Roes. 1995. Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD 19-deficient mice. Nature 376:352.
10. Sato, S., D. A. Steeber, and T. F. Tedder. 1995. The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation. Proc. Natl. Acad. Sci. USA 92:11558.
11. Humphrey, J. H. 1985. Splenic macrophages: Antigen presenting cells for TI-2 antigens. Immunol. Lett. 11:149.
12. Kraal, G., H. Ter Hart, C. Meelhuizen, G. Venneker, and E. Claassen. 1989. Marginal zone macrophages and their role in the immune response against Tndependent type 2 antigens: Modulation of the cells with specific antibody. Ear Eur. J. Immunol. 19:675.
13. Guinamard, R., M. Okigaki, J. Schlessinger and J. V. Ravetch. 2000. Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response. Nat. Immunol. 1:31.
14. Pepys, M. B. 1974. Role of complement in induction of antibody production in vivo: Effect of cobra factor and other C3-reactive agents on thymus-dependent and thymus-independent antibody responses. J. Exp. Med. 140:126.
15. Markham, R. B., A. Nicholson-Weller, G. Schiffman, and D. L. Kasper. 1982. The presence of sialic acid on two related bacterial polysaccharides determines the site of the primary immune response and the effect of complement depletion on the response in mice. J. Immunol. 128:2731.
16. Pryjma, J., and J. H. Humphrey. 1975. Prolonged C3 depletion by cobra venom factor in thymus-deprived mice and its implication for the role of C3 as an essential second signal for B-cell triggering. Immunology 28:569.
17. Griffioen, A. W., G. T. Rijkers, P. Janssens-Korpela, and B. J. Zegers. 1991. Pneumococcal polysaccharides complexed with C3d bind to human B lymphocytes via complement receptor type 2. Infect. Immun. 59:1839.
18. Bird, P., and P. J. Lachmann. 1988. The regulation of IgG subclass production in man: Low serum IgG4 in inherited deficiencies of the classical pathway of C3 activation. Eur. J. Immunol. 18:1217.
19. Wessels, M. R., L. C. Paoletti, D. L. Kasper, J. L. DiFabio, F. Michon, K. Holme, and H. J. Jennings. 1990. Immunogenicity in animals of a polysaccharide-protein conjugate vaccine against type III group B Streptococcus. J. Clin. 86:1428.
20. Guttormsen, H. K., C. J. Baker, M. S. Edwards, L. C. Paoletti, and D. L. Kasper. 1996. Quantitative determination of antibodies to type III group B streptococcal polysaccharide. J. Infect. Dis. 173:142.
21. Ahearn, J. M., M. B. Fischer, D. Croix, S. Goerg, M. Ma, J. Xia, X. Zhou, R. G. Howard, T. L. Rothstein, and M. C. Carroll. 1996. Disruption of the Cr2 locus results in a reduction in B-la cells and in an impaired B cell response to T-dependent antigen. Immunity 4:251.
22. Wang, D., S. M. Wells, A. M. Stall, and E. A. Kabat. 1994. Reaction of germinal centers in the T-cell-independent response to the bacterial polysaccharide α(1>6)dextran. Proc. Natl. Acad Sci. USA 91:2502.
23. Sverremark, E., and C. Fernandez. 1998. Role of T cells and germinal center formation in the generation of immune responses to the thymus-independent carbohydrate dextran B512. J. Immunol. 161:4646.
24. Wang, B., C. Biron, J. She, K. Higgins, M. J. Sunshine, E. Lacy, N. Lonberg, and C. Terhorst. 1994. A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3E gene. Proc. Natl. Acad. Sci. USA 91:9402.
25. Vos, Q., C. M. Snapper, and J. J. Mond. 1999. Heterogeneity in the ability of cytotoxic murine NK cell clones to enhance Ig secretion in vitro. Int. Immunol. 11:159.
26. Martin, F., A. M. Oliver. and J. F. Kearney. 2001. Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 14:617.
27. Molina, H., W. Wong, T. Kinoshita, C. Brenner, S. Foley, and V. M. Holers. 1992. Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1. J. Exp. Med. 175:121.
28. Hasegawa, M., M. Fujimoto, J. C. Poe, D. A. Steeber, and T. F. Tedder. 2001. CD19 can regulate B lymphocyte signal transduction independent of complement activation. J. Immunol. 167:3190.
29. Tierens, A., J. Delabie, L. Michiels, P. Vandenberghe, and C. De Wolf-Peeters. 1999. Marginal-zone B cells in the human lymph node and spleen show somatic hypermutations and display clonal expansion. Blood 93:226.
30. Stahl, P. D., and R. A. Ezekowitz. 1998. The mannose receptor is a pattern recognition receptor involved in host defense. Curr. Opin. Immunol. 10:50.
31. Fischer, M. B., M. Ma, N. C. Hsu, and M. C. Carroll. 1998. Local synthesis of C3 within the splenic lymphoid compartment can reconstitute the impaired immune response in C3-deficient mice. J. Immunol. 160:2619.
32. Verschoor, A., M. A. Brockman, D. M. Knipe, and M. C. Carroll. 2001. Cutting edge: Myeloid complement c3 enhances the humoral response to peripheral viral infection. J. Immunol. 167:2446.
33. Martinez-Pomares, L., M. Kosco-Vilbois, E. Darley, P. Tree, S. Herren, J. Bonnefoy, and S. Gordon. 1996. Fc chimeric protein containing the cysteine-rich domain of the murine mannose receptor binds to macrophages from splenic marginal zone and lymph node subcapsular sinus and to germinal centers. J. Exp. Med. 184:1927.
34. Colino, J., Y. Shen, and C. Snapper. 2002. Dendritic cells pulsed with intact Streptococcus pneumoniae elicit both protein- and polysaccharide-specific immunoglobulin isotype responses in vivo through distinct mechanisms. J. Exp. Med. 195:1.
35. Garcia De Vinuesa, C., A. Gulbranson-Judge, M. Khan, P. O'Leary, M. Cascalho, M. Wabl, G. Klaus, M. Owen, and I. MacLennan. 1999. Dendritic cells associated with plasmablast survival. Eur. J. Immunol. 29:3712.
36. Balazs. M., F. Martin, T. Zhou, and J. Kearney, 2002. Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses. Immunity 17:341.
37. Carter, R. H., and D. T. Fearon. 1992. CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes. Science 256:105.
38. Cariappa, A., M. Tang, C. Parng, E. Nebelitskiy, M. Carroll, K. Georgopoulos. and S. Pillai. 2001. The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21. Immunol. 14:603.