Genomic analysis of the ecdysone steroid signal at metamorphosis onset using ecdysoneless and EcRnull Drosophila melanogaster mutants

Genes and Genomics

Volumn 35, Issue 1, 2013, Pages 21-46

  Davis, Melissa B ^a   Li, Tongruei ^b  

^a University of Georgia ^*  (United States)

^b FUDAN UNIVERSITY   (China)

Author keywords

Ecdysone; Ecdysone receptor; Genome wide; Hormone target genes

Indexed keywords

ECDYSONE; ECDYSONE RECEPTOR; ECDYSTERONE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; EMBRYO; GENE; GENE CONTROL; GENE MUTATION; GENE TARGETING; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENOMICS; INSECT GENOME; METAMORPHOSIS; MUTANT; NONHUMAN; SIGNAL TRANSDUCTION;

DROSOPHILA MELANOGASTER;

EID: 84874417102     PISSN: 19769571     EISSN: 20929293     Source Type: Journal    
DOI: 10.1007/s13258-013-0061-0     Document Type: Article

References (85)

1. Africander D, Verhoog N, Hapgood JP (2011) Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception. Steroids 76:636-652
2. Andres AJ, Thummel CS (1992) Hormones, puffs and flies: the molecular control of metamorphosis by ecdysone. Trends Genet 8:132-138
3. Apple RT, Fristrom JW (1991) 20-Hydroxyecdysone is required for, and negatively regulates, transcription of Drosophila pupal cuticle protein genes. Dev Biol 146:569-582
4. Ashburner M (1967) Patterns of puffing activity in the salivary gland chromosomes of drosophila I. Autosomal puffing patterns in a laboratory stock of Drosophila melanogaster. Chromosoma 21:398-428
5. Ashburner M (1969) Patterns of puffing activity in the salivary gland chromosomes of drosophila II. The X-chromosome puffing patterns of D. melanogaster and D. simulans. Chromosoma 27:47-63
6. Ashburner M (1970) Patterns of puffing activity in the salivary gland chromosomes of drosophila V. Responses to environmental treatments. Chromosoma 31:356-376
7. Ashburner M (1972a) Puffing patterns in Drosophila melanogaster and related species. Results Probl Cell Differ 4:101-151
8. Ashburner M (1972b) Patterns of puffing activity in the salivary gland chromosomes of drosophila VI. Induction by ecdysone in salivary glands of D. melanogaster cultured in vitro. Chromosoma 38:255-281
9. Ashburner M (1974) Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster II. The effects of inhibitors of protein synthesis. Dev Biol 39:141-157
10. Ashburner M (1975) The genetic and hormonal control of puffing in the salivary gland chromosomes of drosophila. Sov J Dev Biol 5:97-107
11. Ashburner M, Chihara C, Meltzer P, Richards G (1974) Temporal control of puffing activity in polytene chromosomes. Cold Spring Harb Symp Quant Biol 38:655-662
12. Beckstead RB, Lam G, Thummel CS (2005) The genomic response to 20-hydroxyecdysone at the onset of Drosophila metamorphosis. Genome Biol 6:R99
13. Bender M, Imam FB, Talbot WS, Ganetzky B, Hogness DS (1997) Drosophila ecdysone receptor mutations reveal functional differences among receptor isoforms. Cell 91:777-788
14. Berreur P, Porcheron P, Moriniere M, Berreur-Bonnenfant J, Belinski-Deutsch S, Busson D, Lamour-Audit C (1984) Ecdysteroids during the third larval instar in 1(3)ecd-1ts, a temperature-sensitive mutant of Drosophila melanogaster. Gen Comp Endocrinol 54:76-84
15. + influx and the acrosome reaction in human sperm. Cell Signal 5:531-538
16. Bramley T (2003) Non-genomic progesterone receptors in the mammalian ovary: some unresolved issues. Reproduction 125:3-15
17. Brown HL, Cherbas L, Cherbas P, Truman JW (2006) Use of time-lapse imaging and dominant negative receptors to dissect the steroid receptor control of neuronal remodeling in drosophila. Development 133:275-285
18. Bryant Z, Subrahmanyan L, Tworoger M, LaTray L, Liu CR, Li MJ, van den Engh G, Ruohola-Baker H (1999) Characterization of differentially expressed genes in purified drosophila follicle cells: toward a general strategy for cell type-specific developmental analysis. Proc Natl Acad Sci USA 96:5559-5564
19. Buijs C, de Vries EG, Mourits MJ, Willemse PH (2008) The influence of endocrine treatments for breast cancer on health-related quality of life. Cancer Treat Rev 34:640-655
20. Buszczak M, Freeman MR, Carlson JR, Bender M, Cooley L, Segraves WA (1999) Ecdysone response genes govern egg chamber development during mid-oogenesis in drosophila. Development 126:4581-4589
21. Carney GE, Bender M (2000) The Drosophila ecdysone receptor (EcR) gene is required maternally for normal oogenesis. Genetics 154:1203-1211
22. Cherbas L, Hu X, Zhimulev I, Belyaeva E, Cherbas P (2003) EcR isoforms in drosophila: testing tissue-specific requirements by targeted blockade and rescue. Development 130:271-284
23. da Huang W, Sherman BT, Stephens R, Baseler MW, Lane HC, Lempicki RA (2008) DAVID gene ID conversion tool. Bioinformation 2:428-430
24. da Huang W, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4:44-57
25. Dahlquist KD, Salomonis N, Vranizan K, Lawlor SC, Conklin BR (2002) GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways. Nat Genet 31:19-20
26. D'Avino PP, Thummel CS (2000) The ecdysone regulatory pathway controls wing morphogenesis and integrin expression during Drosophila metamorphosis. Dev Biol 220:211-224
27. Davis MB, Carney GE, Robertson AE, Bender M (2005) Phenotypic analysis of EcR-A mutants suggests that EcR isoforms have unique functions during drosophila development. Dev Biol 282:385-396
28. Dennis G Jr, Sherman BT, Hosack DA, Yang J, Gao W, Lane HC, Lempicki RA (2003) DAVID: database for annotation, visualization, and integrated discovery. Genome Biol 4:P3
29. Doniger SW, Salomonis N, Dahlquist KD, Vranizan K, Lawlor SC, Conklin BR (2003) MAPPFinder: using gene ontology and GenMAPP to create a global gene-expression profile from microarray data. Genome Biol 4:R7
30. Doughty JC (2011) When to start an aromatase inhibitor: now or later? J Surg Oncol 103:730-738
31. Eberle AN, Mild G, Froidevaux S (2004) Receptor-mediated tumor targeting with radiopeptides Part 1. General concepts and methods: applications to somatostatin receptor-expressing tumors. J Recept Signal Transduct Res 24:319-455
32. Eigenbrot C, Ultsch M, Dubnovitsky A, Abrahmsen L, Hard T (2010) Structural basis for high-affinity HER2 receptor binding by an engineered protein. Proc Natl Acad Sci USA 107:15039-15044
33. Eisen MB, Spellman PT, Brown PO, Botstein D (1998) Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA 95:14863-14868
34. Fassnacht M, Libe R, Kroiss M, Allolio B (2011) Adrenocortical carcinoma: a clinician's update. Nat Rev Endocrinol 7:323-335
35. Gagou ME, Kapsetaki M, Turberg A, Kafetzopoulos D (2002) Stage-specific expression of the chitin synthase DmeChSA and DmeChSB genes during the onset of Drosophila metamorphosis. Insect Biochem Mol Biol 32:141-146
36. Gangadharan C, Thoh M, Manna SK (2010) Late phase activation of nuclear transcription factor kappaB by doxorubicin is mediated by interleukin-8 and induction of apoptosis via FasL. Breast Cancer Res Treat 120:671-683
37. Ganter GK et al (2011) Drosophila male courtship behavior is modulated by ecdysteroids. J Insect Physiol 57:1179-1184
38. Ganter GK et al (2012) Drosophila female precopulatory behavior is modulated by ecdysteroids. J Insect Physiol 58:413-419
39. Garbuzov A, Tatar M (2010) Hormonal regulation of drosophila microRNA let-7 and miR-125 that target innate immunity. Fly (Austin) 4:306-311
40. Garen A, Kauvar L, Lepesant JA (1977) Roles of ecdysone in drosophila development. Proc Natl Acad Sci USA 74:5099-5103
41. Gauhar Z, Sun LV, Hua S, Mason CE, Fuchs F, Li TR, Boutros M, White KP (2009) Genomic mapping of binding regions for the ecdysone receptor protein complex. Genome Res 19:1006-1013
42. Gaziova I, Bonnette PC, Henrich VC, Jindra M (2004) Cell-autonomous roles of the ecdysoneless gene in drosophila development and oogenesis. Development 131:2715-2725
43. Giraudo M, Califano J, Hilliou F, Tran T, Taquet N, Feyereisen R, Le Goff G (2011) Effects of hormone agonists on Sf9 cells, proliferation and cell cycle arrest. PLoS One 6:e25708
44. Gonsalves SE, Neal SJ, Kehoe AS, Westwood JT (2011) Genome-wide examination of the transcriptional response to ecdysteroids 20-hydroxyecdysone and ponasterone A in Drosophila melanogaster. BMC Genomics 12:475
45. Groeneweg FL, Karst H, de Kloet ER, Joels M (2011) Rapid non-genomic effects of corticosteroids and their role in the central stress response. J Endocrinol 209:153-167
46. Hayes E, Nicholson RI, Hiscox S (2011) Acquired endocrine resistance in breast cancer: implications for tumour metastasis. Front Biosci 16:838-848
47. Henrich VC, Livingston L, Gilbert LI (1993) Developmental requirements for the ecdysoneless (ecd) locus in Drosophila melanogaster. Dev Genet 14:369-377
48. Henrich VC, Rybczynski R, Gilbert LI (1999) Peptide hormones, steroid hormones, and puffs: mechanisms and models in insect development. Vitam Horm 55:73-125
49. Hospers GA, Helmond FA, de Vries EG, Dierckx RA, de Vries EF (2008) PET imaging of steroid receptor expression in breast and prostate cancer. Curr Pharm Des 14:3020-3032
50. Huet F, Ruiz C, Richards G (1993) Puffs and PCR: the in vivo dynamics of early gene expression during ecdysone responses in drosophila. Development 118:613-627
51. Huet F, Ruiz C, Richards G (1995) Sequential gene activation by ecdysone in Drosophila melanogaster: the hierarchical equivalence of early and early late genes. Development 121:1195-1204
52. Jiang C, Lamblin AF, Steller H, Thummel CS (2000) A steroid-triggered transcriptional hierarchy controls salivary gland cell death during Drosophila metamorphosis. Mol Cell 5:445-455
53. Jochova J, Zakeri Z, Lockshin RA (1997) Rearrangement of the tubulin and actin cytoskeleton during programmed cell death in drosophila salivary glands. Cell Death Differ 4:140-149
54. Johnston DM, Sedkov Y, Petruk S, Riley KM, Fujioka M, Jaynes JB, Mazo A (2011) Ecdysone- and NO-mediated gene regulation by competing EcR/Usp and E75A nuclear receptors during drosophila development. Mol Cell 44:51-61
55. Kim HS, Freedland SJ (2010) Androgen deprivation therapy in prostate cancer: anticipated side-effects and their management. Curr Opin Support Palliat Care 4:147-152
56. Kozlova T, Thummel CS (2000) Steroid regulation of postembryonic development and reproduction in drosophila. Trends Endocrinol Metab 11:276-280
57. Kozlova T, Thummel CS (2002) Spatial patterns of ecdysteroid receptor activation during the onset of Drosophila metamorphosis. Development 129:1739-1750
58. Lam G, Hall BL, Bender M, Thummel CS (1999) DHR3 is required for the prepupal-pupal transition and differentiation of adult structures during Drosophila metamorphosis. Dev Biol 212:204-216
59. Li T, Bender M (2000) A conditional rescue system reveals essential functions for the ecdysone receptor (EcR) gene during molting and metamorphosis in drosophila. Development 127:2897-2905
60. Li TR, White KP (2003) Tissue-specific gene expression and ecdysone regulated genomic networks in drosophila. Dev Cell 5:59-72
61. Li H, Harrison D, Jones G, Jones D, Cooper RL (2001) Alterations in development, behavior, and physiology in drosophila larva that have reduced ecdysone production. J Neurophysiol 85:98-104
62. Losel R, Feuring M, Wehling M (2002) Non-genomic aldosterone action: from the cell membrane to human physiology. J Steroid Biochem Mol Biol 83:167-171
63. McEwen BS (1991) Non-genomic and genomic effects of steroids on neural activity. Trends Pharmacol Sci 12:141-147
64. Morimoto S, Morales A, Zambrano E, Fernandez-Mejia C (2010) Sex steroids effects on the endocrine pancreas. J Steroid Biochem Mol Biol 122:107-113
65. Mosallanejad H, Badisco L, Swevers L, Soin T, Knapen D, Vanden Broeck J, Smagghe G (2010) Ecdysone signaling and transcript signature in drosophila cells resistant against methoxyfenozide. J Insect Physiol 56:1973-1985
66. Napieralski R, Brunner N, Mengele K, Schmitt M (2010) Emerging biomarkers in breast cancer care. Biomark Med 4:505-522
67. Rafiq K, Hitomi H, Nakano D, Nishiyama A (2011) Pathophysiological roles of aldosterone and mineralocorticoid receptor in the kidney. J Pharmacol Sci 115:1-7
68. Rainer J, Sanchez-Cabo F, Stocker G, Sturn A, Trajanoski Z (2006) CARMAweb: comprehensive R- and bio-conductor-based web service for microarray data analysis. Nucleic Acids Res 34:W498-W503
69. Riddiford LM, Cherbas P, Truman JW (2000) Ecdysone receptors and their biological actions. Vitam Horm 60:1-73
70. Roth GE, Wattler S, Bornschein H, Lehmann M, Korge G (1999) Structure and regulation of the salivary gland secretion protein gene Sgs-1 of Drosophila melanogaster. Genetics 153:753-762
71. Schubiger M, Wade AA, Carney GE, Truman JW, Bender M (1998) Drosophila EcR-B ecdysone receptor isoforms are required for larval molting and for neuron remodeling during metamorphosis. Development 125:2053-2062
72. Smyth GK (2005) Limma: linear models for microarray data. In: Gentleman R, Dudoit S, Irizarry R, Huber W (eds) Bioinformatics and computational biology solutions using R and bio-conductor, vol 1. Springer, New York, pp 397-420
73. Smyth GK, Speed T (2003) Normalization of cDNA microarray data. Methods 31:265-273
74. Soin T, Swevers L, Kotzia G, Iatrou K, Janssen CR, Rouge P, Harada T, Nakagawa Y, Smagghe G (2010) Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays. Pest Manag Sci 66:1215-1229
75. Terashima J, Bownes M (2005) A microarray analysis of genes involved in relating egg production to nutritional intake in Drosophila melanogaster. Cell Death Differ 12:429-440
76. Thummel CS (2002) Ecdysone-regulated puff genes 2000. Insect Biochem Mol Biol 32:113-120
77. Tian L, Guo E, Diao Y, Zhou S, Peng Q, Cao Y, Ling E, Li S (2010) Genome-wide regulation of innate immunity by juvenile hormone and 20-hydroxyecdysone in the Bombyx fat body. BMC Genomics 11:549
78. Toft DJ, Cryns VL (2011) Minireview: basal-like breast cancer: from molecular profiles to targeted therapies. Mol Endocrinol 25:199-211
79. van den Berg NS, Buckle T, Kuil J, Wesseling J, van Leeuwen FW (2011) Immunohistochemical detection of the CXCR4 expression in tumor tissue using the fluorescent peptide antagonist Ac-TZ14011-FITC. Transl Oncol 4:234-240
80. Vaquerizas JM, Dopazo J, Diaz-Uriarte R (2004) DNMAD: web-based diagnosis and normalization for microarray data. Bioinformatics 20:3656-3658
81. Warren JT, Bachmann JS, Dai JD, Gilbert LI (1996) Differential incorporation of cholesterol and cholesterol derivatives into ecdysteroids by the larval ring glands and adult ovaries of Drosophila melanogaster: a putative explanation for the l(3)ecd1 mutation. Insect Biochem Mol Biol 26:931-943
82. Warren JT, Yerushalmi Y, Shimell MJ, O'Connor MB, Restifo LL, Gilbert LI (2006) Discrete pulses of molting hormone, 20-hydroxyecdysone, during late larval development of Drosophila melanogaster: correlations with changes in gene activity. Dev Dyn 235:315-326
83. Wehling M, Losel R (2006) Non-genomic steroid hormone effects: membrane or intracellular receptors? J Steroid Biochem Mol Biol 102:180-183
84. Wettenhall JM, Smyth GK (2004) LimmaGUI: a graphical user interface for linear modeling of microarray data. Bioinformatics 20:3705-3706
85. White KP, Rifkin SA, Hurban P, Hogness DS (1999) Microarray analysis of drosophila development during metamorphosis. Science 286:2179-2184