Gene therapy with an erythropoietin enhancer-mediated, hypoxia-inducible gene expression system in the corpus cavernosum of mice with high-cholesterol diet-induced erectile dysfunction

Journal of Andrology

Volumn 33, Issue 5, 2012, Pages 845-853

  Ryu, Ji Kan ^a,b   Lee, Minhyung ^b   Choi, Min Ji ^a   Kim, Hyun Ah ^b   Jin, Hai Rong ^a   Kim, Woo Jean ^a   Yin, Guo Nan ^a   Song, Kang Moon ^a   Kwon, Mi Hye ^a   Suh, Jun Kyu ^a  

^a Inha University School of Medicine   (South Korea)

^b Hanyang University   (South Korea)

Author keywords

Hypercholesterolemia; Hypoxia response element; Vector

Indexed keywords

CHOLIC ACID; HYPOXIA INDUCIBLE FACTOR; RECOMBINANT ERYTHROPOIETIN; DDIT4L PROTEIN, MOUSE; DNA BINDING PROTEIN; ERYTHROPOIETIN; HIF1A PROTEIN, MOUSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CHOLESTEROL DIET; CONTROLLED STUDY; CORPUS CAVERNOSUM; ENDOTHELIUM CELL; ERECTILE DYSFUNCTION; GENE EXPRESSION; GENE THERAPY; HYPERCHOLESTEROLEMIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BIOSYNTHESIS; BLOOD VESSEL; C57BL MOUSE; CELL HYPOXIA; CHOLESTEROL INTAKE; DISEASE MODEL; ENHANCER REGION; GENETIC TRANSFECTION; GENETICS; METABOLISM; ORGANIC IMPOTENCE; PATHOPHYSIOLOGY; PENIS; PENIS ERECTION; PROMOTER REGION; REPORTER GENE; TIME; UPREGULATION; VASCULARIZATION;

ANIMALS; BLOOD VESSELS; CELL HYPOXIA; CELLS, CULTURED; CHOLESTEROL, DIETARY; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; ENDOTHELIAL CELLS; ENHANCER ELEMENTS, GENETIC; ERYTHROPOIETIN; GENES, REPORTER; GENETIC THERAPY; HYPERCHOLESTEROLEMIA; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; IMPOTENCE, VASCULOGENIC; MALE; MICE; MICE, INBRED C57BL; PENILE ERECTION; PENIS; PROMOTER REGIONS, GENETIC; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION; UP-REGULATION;

EID: 84874410790     PISSN: 01963635     EISSN: 19394640     Source Type: Journal    
DOI: 10.2164/jandrol.111.016014     Document Type: Article

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