Gene transfer of endothelial nitric oxide synthase to the penis 3 augments erectile responses in the aged rat

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 20, 1999, Pages 11648-11652

  Champion, H C ^a   Bivalacqua, T J ^a   Hyman, A L ^a   Ignarro, L J ^b   Hellstrom, W J G ^a   Kadowitz, P J ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; BETA GALACTOSIDASE; CYCLIC GMP; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHODIESTERASE INHIBITOR; ZAPRINAST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS CAVERNOSUM; ERECTILE DYSFUNCTION; GENE ACTIVITY; GENE OVEREXPRESSION; GENE THERAPY; GENE TRANSFER; MALE; NERVE STIMULATION; NONHUMAN; PENIS ERECTION; PRIORITY JOURNAL; RAT; REPORTER GENE; TRANSGENE;

ACETYLCHOLINE; ADENOVIRIDAE; AGING; ANIMALS; CYCLIC GMP; ELECTRIC STIMULATION; GENE THERAPY; GENE TRANSFER TECHNIQUES; IMPOTENCE; MALE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PENIS; PURINONES; RATS; RATS, SPRAGUE-DAWLEY;

ADENOVIRIDAE; ANIMALIA;

EID: 0033613191     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.20.11648     Document Type: Article

References (26)

1. National Institutes of Health Consensus Conference (1993) J. Am. Med. Assoc. 270, 83-89.
2. Feldman, H. A., Goldstein, I., Hatzichristou, D. G., Krane, R. J. & McKinlay, J. B. (1994) J. Urol. 151, 54-61.
3. Burnett, A. L. (1995) Biol. Reprod. 52, 485-489.
4. Rajfer, J., Aronson, W. J., Bush, P. A., Dorey, F. J. & Ignarro, L. J. (1992) N. Engl. J. Med. 326, 90-94.
5. Anderson, K. E. (1993) Pharmacol. Rev. 45, 253-308.
6. Andersson, K. E. & Wagner G. (1995) Physiol. Rev. 75, 191-236.
7. Ignarro, L. J. (1996) Kidney Int. 55, S2-S5.
8. Burnett, A. L., Lowenstein, C. J., Bredt, D. S., Chang, T. S. & Snyder, S. H. (1992) Science 257, 401-403.
9. Melis, M. R. & Argiolas, A. (1997) Prog. Neuropsychopharmacol. Biol. Psychiatry 21, 899-922.
10. Melis, M. R., Succu, S. & Argiolas A. (1996) Eur. J. Neurosci. 8, 2056-2063.
11. Ignarro, L. J., Bush, P. A., Buga, G. M., Wood, K. S., Fukuto, J. M. & Rajfer, J. (1990) Biochem. Biophys. Res. Commun. 170, 843-850.
12. Bush, P. A., Aronson, W. J., Buga, G. M., Rajfer, J. & Ignarro, L. J. (1992) J. Urol. 147, 1650-1655.
13. Champion, H. C., Bivalacqua, T. J., Wang, R., Kadowitz, P. J., Keefer, L. K., Saavedra, J. E., Hrabie, J. A., Doherty, P. C. & Hellstrom, W. J. G. (1999) J. Urol. 161, 2013-2019.
14. Burnett, A. L. (1995) Urology 45, 1071-1083.
15. Christ, G. J., Rehman, J., Day, N., Salkoff, L., Valcic, M., Melman, A. & Geliebter, J. (1998) Am. J. Physiol. 275, H600-H608.
16. Christ, G. J. & Melman, A. (1998) Int. J. Impotence Res. 10, 111-112.
17. Garban, H., Marquez, D., Magee, T., Moody, J., Rajavashisth, T., Rodriguez, J. A., Hung, A., Vernet, D., Rajfer, J. & Gonzalez-Cadavid, N. F. (1997) Biol. Reprod. 56, 954-963.
18. Ooboshi, H., Chu, Y., Rios, C. D., Faraci, F. M., Davidson, B. L. & Heistad, D. D. (1997) Am. J. Physiol. 273, H265-H270.
19. Ooboshi, H., Toyoda, K., Faraci, F. M., Lang, M. G. & Heistad, D. D. (1998) Arterioscler. Thromb. Vasc. Biol. 18, 1752-1758.
20. Rodman, D. M., San, H., Simari, R., Stephan, D., Tanner, F., Yang, Z., Nabel, G. J. & Nabel, E. G. (1997) Am. J. Respir. Cell Mol. Biol. 16, 640-649.
21. Janssens, S. P., Bloch, K. D., Nong, Z., Gerard, R. D., Zoldhelyi, P. & Collen, D. (1996) J. Clin. Invest. 98, 327-324.
22. Kaplan, J. M., Pennington, S. E., St. George, J. A., Woodworth, L. A., Fasbender, A., Marshall, J., Cheng, S. H., Wadsworth, S. C., Gregory, R. J. & Smith, A. E. (1998) Hum. Gene Ther. 9, 1469-1479.
23. Champion, H. C., Bivalacqua, T. J., D'Souza, F. M., Ortiz, L. A., Jeter, J. R., Toyoda, K., Heistad, D. D., Hyman, A. L. & Kadowitz, P. J. (1999) Circ. Res. 84, 1422-1432.
24. Burnett, A. L., Lowenstein, C. J., Bredt, D. S., Chang, T. S. & Snyder, S. H. (1992) Mol. Med. 2, 288-296.
25. Garban, H., Vernet, D., Freedman, A., Rajfer, J. & Gonzalez-Cadavid, N. (1995) Am. J. Physiol. 268, H467-H475.
26. Vernet, D., Cai, L., Garban, H., Babbitt, M. L., Murray, F. T., Rajfer, J. & Gonzalez-Cadavid, N. F. (1995) Endocrinology 136, 5709-5717.