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Volumn 10, Issue 2, 1998, Pages 113-120

Is there a role of hypoxemia in penile fibrosis: A viewpoint presented to the Society for the Study of Impotence

Author keywords

cAMP; Collagen; Corpus cavernosum; Erectile dysfunction; Hypoxemia; PGE1; TGF 1; Vascular smooth muscle

Indexed keywords

PROSTAGLANDIN E; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0031805037     PISSN: 09559930     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ijir.3900328     Document Type: Review
Times cited : (276)

References (56)
  • 1
    • 0027533216 scopus 로고
    • Oxygen tension regulates the nitric oxide pathway: Physiological role in penile erection
    • Kim N et al. Oxygen tension regulates the nitric oxide pathway: Physiological role in penile erection. j Clin Invest 1993; 91: 437-443.
    • (1993) J Clin Invest , vol.91 , pp. 437-443
    • Kim, N.1
  • 2
    • 9544258245 scopus 로고    scopus 로고
    • Mechanisms of venous leakage: A prospective clinicopathological correlation of corporeal function and structure
    • Nehra A et al. Mechanisms of venous leakage: a prospective clinicopathological correlation of corporeal function and structure. J Urol 1996; 156: 1320-1329.
    • (1996) J Urol , vol.156 , pp. 1320-1329
    • Nehra, A.1
  • 3
    • 0028860594 scopus 로고
    • The epidemiology of erectile dysfunction
    • Benet AE, Melman A. The epidemiology of erectile dysfunction. Urol Clin N Am 1995; 22: 699-709.
    • (1995) Urol Clin N Am , vol.22 , pp. 699-709
    • Benet, A.E.1    Melman, A.2
  • 4
    • 0028036149 scopus 로고
    • Impotence and its medical and psychosocial correlates: Results of the Massachusetts Male Aging Study
    • Feldman HA et al. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol 1994; 151: 54-61.
    • (1994) J Urol , vol.151 , pp. 54-61
    • Feldman, H.A.1
  • 5
    • 0029000676 scopus 로고
    • Blunt trauma: The pathophysiology of hemodynamic injury leading to erectile dysfunction
    • Munarriz RM et al. Blunt trauma: the pathophysiology of hemodynamic injury leading to erectile dysfunction. J Urol 1995; 153: 1831-1840.
    • (1995) J Urol , vol.153 , pp. 1831-1840
    • Munarriz, R.M.1
  • 6
    • 84907126253 scopus 로고
    • Pudendal artery syndrome with erectile dysfunction: Treatment by pudendal canal decompression
    • Shafik A. Pudendal artery syndrome with erectile dysfunction: treatment by pudendal canal decompression. Arch Androl 1995; 34: 83-94.
    • (1995) Arch Androl , vol.34 , pp. 83-94
    • Shafik, A.1
  • 7
    • 0024791916 scopus 로고
    • Correlation of altered penile ultrastructure with clinical arterial evaluation
    • Persson C et al. Correlation of altered penile ultrastructure with clinical arterial evaluation. J Urol 1989; 142: 1462-1468.
    • (1989) J Urol , vol.142 , pp. 1462-1468
    • Persson, C.1
  • 8
    • 0025098939 scopus 로고
    • Clinical significance of ultrastructural findings in the corpus cavernosa of normal and impotent men
    • Jevtich M, Khawand NY, Vidic B. Clinical significance of ultrastructural findings in the corpus cavernosa of normal and impotent men. J Urol 1990; 143: 289-293.
    • (1990) J Urol , vol.143 , pp. 289-293
    • Jevtich, M.1    Khawand, N.Y.2    Vidic, B.3
  • 9
    • 0025826729 scopus 로고
    • Ultrastructural changes in impotent penile tissue: A comparison of 65 patients
    • Mersdorf A et al. Ultrastructural changes in impotent penile tissue: a comparison of 65 patients J Urol 1991; 145: 749-758.
    • (1991) J Urol , vol.145 , pp. 749-758
    • Mersdorf, A.1
  • 10
    • 0026050946 scopus 로고
    • Computerized analysis of smooth muscle fibers in potent and impotent patients
    • Wespes E et al. Computerized analysis of smooth muscle fibers in potent and impotent patients. J Urol 1991; 146: 1015-1017.
    • (1991) J Urol , vol.146 , pp. 1015-1017
    • Wespes, E.1
  • 11
    • 0026782915 scopus 로고
    • Collagen alterations in the corpus cavernosum of men with sexual dysfunction
    • Luangkhot R et al. Collagen alterations in the corpus cavernosum of men with sexual dysfunction. J Urol 1992; 148: 467-471.
    • (1992) J Urol , vol.148 , pp. 467-471
    • Luangkhot, R.1
  • 12
    • 0028936694 scopus 로고
    • In vivo assessment of trabecular smooth muscle tone, it's application in pharmacocavernosometry and analysis of intracavernosal pressure determinants
    • Hatzichristou DG et al. In vivo assessment of trabecular smooth muscle tone, it's application in pharmacocavernosometry and analysis of intracavernosal pressure determinants. J Urol 1995; 153: 1126-1131.
    • (1995) J Urol , vol.153 , pp. 1126-1131
    • Hatzichristou, D.G.1
  • 14
    • 0028836204 scopus 로고
    • 1 in human corpus cavernosum smooth muscle
    • 1 in human corpus cavernosum smooth muscle. J Urol 1995; 153: 826-834.
    • (1995) J Urol , vol.153 , pp. 826-834
    • Moreland, R.B.1
  • 15
    • 0025847582 scopus 로고
    • Matrix metalloproteinases and their inhibitors in connective tissue remodeling
    • Woessner JF. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J 1991; 5: 2145-2154.
    • (1991) FASEB J , vol.5 , pp. 2145-2154
    • Woessner, J.F.1
  • 16
    • 0026778310 scopus 로고
    • Transforming growth factor-β in disease: The dark side of tissue repair
    • Border WA, Ruoslahti E. Transforming growth factor-β in disease: the dark side of tissue repair. J Clin Inv 1992; 90: 1-7.
    • (1992) J Clin Inv , vol.90 , pp. 1-7
    • Border, W.A.1    Ruoslahti, E.2
  • 17
    • 0028109801 scopus 로고
    • Transforming growth factor β in tissue fibrosis
    • Border WA, Noble NA. Transforming growth factor β in tissue fibrosis. New Engl J Med 1994; 331: 1286-1291.
    • (1994) New Engl J Med , vol.331 , pp. 1286-1291
    • Border, W.A.1    Noble, N.A.2
  • 18
    • 0023368573 scopus 로고
    • Beta-type transforming growth factor specifies organizational behavior in vascular smooth muscle cell cultures
    • Majack RA. Beta-type transforming growth factor specifies organizational behavior in vascular smooth muscle cell cultures. J Cell Biol 1987; 105: 465-471.
    • (1987) J Cell Biol , vol.105 , pp. 465-471
    • Majack, R.A.1
  • 20
    • 0027497117 scopus 로고
    • Direct transfer of transforming growth factor beta 1 gene into arteries stimulates fibrocellular hyperplasia
    • Nabel EG et al. Direct transfer of transforming growth factor beta 1 gene into arteries stimulates fibrocellular hyperplasia. Proc Natl Acad Sci USA 1993; 90: 10759-10763.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10759-10763
    • Nabel, E.G.1
  • 22
    • 0031667129 scopus 로고    scopus 로고
    • 1-induced fibrillar collagen synthesis in cultured human corpus cavernosum smooth muscle cells
    • in press
    • 1-induced fibrillar collagen synthesis in cultured human corpus cavernosum smooth muscle cells. Int J Imp Res 1998, in press.
    • (1998) Int J Imp Res
    • Moreland, R.B.1
  • 24
    • 0024563645 scopus 로고
    • Vascular smooth muscle cells express distinct transforming growth factor-β receptor phenotypes as a function of cell density
    • Goodman LV, Majack RA. Vascular smooth muscle cells express distinct transforming growth factor-β receptor phenotypes as a function of cell density. J Biol Chem 1989; 264: 5241-5244.
    • (1989) J Biol Chem , vol.264 , pp. 5241-5244
    • Goodman, L.V.1    Majack, R.A.2
  • 25
    • 0018832895 scopus 로고
    • Effect of cyclic AMP on the intracellular degradation of newly synthesized collagen
    • Baum BJ et al. Effect of cyclic AMP on the intracellular degradation of newly synthesized collagen. J Biol Chem 1980; 255: 2843-2847.
    • (1980) J Biol Chem , vol.255 , pp. 2843-2847
    • Baum, B.J.1
  • 26
    • 0024325755 scopus 로고
    • 2 on transforming growth factor-β and insulin-induced collagen formation in lung fibroblasts
    • 2 on transforming growth factor-β and insulin-induced collagen formation in lung fibroblasts. J Biol Chem 1989; 264: 16988-16991.
    • (1989) J Biol Chem , vol.264 , pp. 16988-16991
    • Fine, A.1
  • 27
    • 0028924146 scopus 로고
    • 2 and to express cyclooxygenase-2
    • 2 and to express cyclooxygenase-2. J Clin Inv 1995; 95: 1861-1868.
    • (1995) J Clin Inv , vol.95 , pp. 1861-1868
    • Wilborn, J.1
  • 28
    • 0028269736 scopus 로고
    • Protection of rabbit lungs from endotoxin injury by in vivo hyperexpression of the prostaglandin G/H synthase gene
    • Conary JT et al. Protection of rabbit lungs from endotoxin injury by in vivo hyperexpression of the prostaglandin G/H synthase gene. J Clin Inv 1994; 93: 1834-1840.
    • (1994) J Clin Inv , vol.93 , pp. 1834-1840
    • Conary, J.T.1
  • 29
    • 0021241091 scopus 로고
    • Ability of human corpus cavernosum to generate prostaglandins and thromboxanes in vitro
    • Roy AC, Tan SM, Kottegoda SR, Ratnam SS. Ability of human corpus cavernosum to generate prostaglandins and thromboxanes in vitro. IRCS Med Sci 1984; 12: 608.
    • (1984) IRCS Med Sci , vol.12 , pp. 608
    • Roy, A.C.1    Tan, S.M.2    Kottegoda, S.R.3    Ratnam, S.S.4
  • 30
    • 0029927564 scopus 로고    scopus 로고
    • Prostanoid production in rabbit corpus cavernosum I. Regulation by oxygen tension
    • Daley JT et al. Prostanoid production in rabbit corpus cavernosum I. Regulation by oxygen tension. J Urol 1996; 155: 1482-1487.
    • (1996) J Urol , vol.155 , pp. 1482-1487
    • Daley, J.T.1
  • 31
    • 0029912525 scopus 로고    scopus 로고
    • Study of etiologic relationship of arterial atherosclerosis to corporal veno-occlusive dysfunction in the rabbit
    • Azadzoi KM, Siroky MB, Goldstein I. Study of etiologic relationship of arterial atherosclerosis to corporal veno-occlusive dysfunction in the rabbit. J Urol 1996; 155: 1795-1800.
    • (1996) J Urol , vol.155 , pp. 1795-1800
    • Azadzoi, K.M.1    Siroky, M.B.2    Goldstein, I.3
  • 32
    • 0027958541 scopus 로고
    • Experimental hypercholesterolemia in rabbits induces cavernosal atherosclerosis with endothelial and smooth muscle cell dysfunction
    • Kim JH et al. Experimental hypercholesterolemia in rabbits induces cavernosal atherosclerosis with endothelial and smooth muscle cell dysfunction. J Urol 1994; 151: 198-205.
    • (1994) J Urol , vol.151 , pp. 198-205
    • Kim, J.H.1
  • 33
    • 0031030804 scopus 로고    scopus 로고
    • Relationship between cavernosal ischemia and corporal veno-occlusive dysfunction in an animal model
    • Azadzoi KM et al. Relationship between cavernosal ischemia and corporal veno-occlusive dysfunction in an animal model. J Urol 1997; 157: 1011-1017.
    • (1997) J Urol , vol.157 , pp. 1011-1017
    • Azadzoi, K.M.1
  • 34
    • 0032426699 scopus 로고    scopus 로고
    • Cavernosal expandability is an erectile tissue mechanical property which predicts trabecular histology in an animal model of vasculogenic erectile dysfunction
    • in press
    • Nehra A et al. Cavernosal expandability is an erectile tissue mechanical property which predicts trabecular histology in an animal model of vasculogenic erectile dysfunction. J Urol 1998, in press.
    • (1998) J Urol
    • Nehra, A.1
  • 35
    • 0345500006 scopus 로고    scopus 로고
    • 1 mediated cavernosal fibrosis is modulated by econsanoids
    • Abstract A36
    • 1 mediated cavernosal fibrosis is modulated by econsanoids. Int J Imp Res 1996; 8: 108 (Abstract A36).
    • (1996) Int J Imp Res , vol.8 , pp. 108
    • Azadzoi, K.M.1
  • 36
    • 0026564199 scopus 로고
    • Diabetes mellitus impairs neurogenic and endothelium-dependent relaxation of rabbit corpus cavernosum smooth muscle
    • Azadzoi KM, Saenz de Tejada I. Diabetes mellitus impairs neurogenic and endothelium-dependent relaxation of rabbit corpus cavernosum smooth muscle. J Urol 1992; 148: 1587-1591.
    • (1992) J Urol , vol.148 , pp. 1587-1591
    • Azadzoi, K.M.1    De Saenz Tejada, I.2
  • 37
    • 0000025591 scopus 로고    scopus 로고
    • Diabetes-induced structural changes in rabbit corpus cavernosum
    • Abstract D55
    • Gupta S et al. Diabetes-induced structural changes in rabbit corpus cavernosum. Int J Imp Res 1996; 8: 136 (Abstract D55).
    • (1996) Int J Imp Res , vol.8 , pp. 136
    • Gupta, S.1
  • 38
    • 4243992632 scopus 로고    scopus 로고
    • 1 induced corporal fibrosis: Implications for penile ischemiaassisted fibrosis
    • Abstract 1243
    • 1 induced corporal fibrosis: implications for penile ischemiaassisted fibrosis. J Urol 1996; 155: 622A (Abstract 1243).
    • J Urol 1996 , vol.155
    • Nehra, A.1
  • 39
    • 0030444318 scopus 로고    scopus 로고
    • Androgens and penile erection: A review
    • Mills TM, Reilly CM, Lewis RW. Androgens and penile erection: a review. J Androl 1996; 17: 633-638.
    • (1996) J Androl , vol.17 , pp. 633-638
    • Mills, T.M.1    Reilly, C.M.2    Lewis, R.W.3
  • 40
    • 0027276454 scopus 로고
    • Sexual function does not change when serum testosterone levels are pharmacologically varied within the normal male range
    • Buena F et al. Sexual function does not change when serum testosterone levels are pharmacologically varied within the normal male range. Fertil Steril 1995; 59: 1118-1123.
    • (1995) Fertil Steril , vol.59 , pp. 1118-1123
    • Buena, F.1
  • 41
    • 0028824137 scopus 로고
    • Effect of raising endogenous testosterone levels in impotent men with secondary hypergonadism: Double blind placebo-controlled trial with clomiphene citrate
    • Guay AT, Bansal S, Heatley GJ. Effect of raising endogenous testosterone levels in impotent men with secondary hypergonadism: double blind placebo-controlled trial with clomiphene citrate. Clin Endocrinol Metab 1995; 80: 3546-3552.
    • (1995) Clin Endocrinol Metab , vol.80 , pp. 3546-3552
    • Guay, A.T.1    Bansal, S.2    Heatley, G.J.3
  • 42
    • 0031022767 scopus 로고    scopus 로고
    • Testosterone supplementation for hypogonadal impotence: Assessment of biochemical measures and therapeutic outcomes
    • Morales A, Johnston B, Heaton JP, Lundie M. Testosterone supplementation for hypogonadal impotence: assessment of biochemical measures and therapeutic outcomes. J Urol 1997; 157: 849-854.
    • (1997) J Urol , vol.157 , pp. 849-854
    • Morales, A.1    Johnston, B.2    Heaton, J.P.3    Lundie, M.4
  • 43
    • 0029812277 scopus 로고    scopus 로고
    • Androgen and pituitary control of penile nitric oxide synthase and erectile function in the rat
    • Penson DF et al. Androgen and pituitary control of penile nitric oxide synthase and erectile function in the rat. Biol Reprod 1996; 55: 567-574.
    • (1996) Biol Reprod , vol.55 , pp. 567-574
    • Penson, D.F.1
  • 44
    • 0031019544 scopus 로고    scopus 로고
    • Localization of androgen receptor in nitric oxide synthase- and vasoactive intestinal peptide-containing neurons of the major pelvic ganglion innervating the rat penis
    • Schirar A, Chang C, Rousseau JP. Localization of androgen receptor in nitric oxide synthase- and vasoactive intestinal peptide-containing neurons of the major pelvic ganglion innervating the rat penis. J Neuroendocrinol 1997; 9: 141-150.
    • (1997) J Neuroendocrinol , vol.9 , pp. 141-150
    • Schirar, A.1    Chang, C.2    Rousseau, J.P.3
  • 45
    • 0031013228 scopus 로고    scopus 로고
    • Age decreases nitric oxide synthase-containing nerve fibers in the rat penis
    • Carrier S et al. Age decreases nitric oxide synthase-containing nerve fibers in the rat penis. J Urol 1997; 157: 1088-1092.
    • (1997) J Urol , vol.157 , pp. 1088-1092
    • Carrier, S.1
  • 46
    • 9444295328 scopus 로고    scopus 로고
    • Nitric oxide-dependent penile erection in mice lacking neuronal nitric oxide synthase
    • Burnett AL et al. Nitric oxide-dependent penile erection in mice lacking neuronal nitric oxide synthase. Mol Med 1996; 2: 288-296.
    • (1996) Mol Med , vol.2 , pp. 288-296
    • Burnett, A.L.1
  • 47
    • 0007576872 scopus 로고
    • Genital and sphincter behavior of the male infant
    • Halverson HM. Genital and sphincter behavior of the male infant. J Gen Psychol 1940; 56: 95.
    • (1940) J Gen Psychol , vol.56 , pp. 95
    • Halverson, H.M.1
  • 48
    • 0029009748 scopus 로고
    • Penile tumescence in the human fetus at term - A preliminary report
    • Shirozu H et al. Penile tumescence in the human fetus at term - a preliminary report. Early Hum Dev 1995; 41: 159-166.
    • (1995) Early Hum Dev , vol.41 , pp. 159-166
    • Shirozu, H.1
  • 49
    • 76549185088 scopus 로고
    • Cycle of penile erections synchronous with dreaming (REM) sleep: Preliminary report
    • Fischer C, Gross J, Zuch J. Cycle of penile erections synchronous with dreaming (REM) sleep: preliminary report. Arch Gen Psychiatry 1965; 12: 29-45.
    • (1965) Arch Gen Psychiatry , vol.12 , pp. 29-45
    • Fischer, C.1    Gross, J.2    Zuch, J.3
  • 50
    • 0027258621 scopus 로고
    • Hormones and nocturnal penile tumescence in healthy aging men
    • Schiavi RC et al. Hormones and nocturnal penile tumescence in healthy aging men. Arch Sex Behav 1993; 22: 207-215.
    • (1993) Arch Sex Behav , vol.22 , pp. 207-215
    • Schiavi, R.C.1
  • 51
    • 0025147945 scopus 로고
    • Prevalence of sleep apnea in men with erectile dysfunction
    • Hirshkowitz M et al. Prevalence of sleep apnea in men with erectile dysfunction. Urology 1990; 36: 232-234.
    • (1990) Urology , vol.36 , pp. 232-234
    • Hirshkowitz, M.1
  • 52
    • 0022845421 scopus 로고
    • Erectile dysfunction in narcoleptic patients
    • Karacan I. Erectile dysfunction in narcoleptic patients. Sleep 1986; 9: 227-231.
    • (1986) Sleep , vol.9 , pp. 227-231
    • Karacan, I.1
  • 53
    • 0029808492 scopus 로고    scopus 로고
    • Nocturnal penile tumescence and rigidity evaluation in men with epilepsy
    • Guldner GT, Morrell MJ. Nocturnal penile tumescence and rigidity evaluation in men with epilepsy. Epilepsia 1996; 37: 1211-1214.
    • (1996) Epilepsia , vol.37 , pp. 1211-1214
    • Guldner, G.T.1    Morrell, M.J.2
  • 54
    • 0029621770 scopus 로고
    • Erectile dysfunction in sleep apnea and response to CPAP
    • Karacan I, Karatas M. Erectile dysfunction in sleep apnea and response to CPAP. J Sex and Marital Therapy 1995; 21: 239-247.
    • (1995) J Sex and Marital Therapy , vol.21 , pp. 239-247
    • Karacan, I.1    Karatas, M.2
  • 55
    • 0030865724 scopus 로고    scopus 로고
    • Recovery of spontaneous erectile function after nerve-sparing radical retropubic prostatectomy with and without early intracavernous injections of Alprostadil: Results of a prospective randomized trial
    • Montorsi F et al. Recovery of spontaneous erectile function after nerve-sparing radical retropubic prostatectomy with and without early intracavernous injections of Alprostadil: Results of a prospective randomized trial. J Urol 1997; 158: 1408-1410.
    • (1997) J Urol , vol.158 , pp. 1408-1410
    • Montorsi, F.1


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