Targeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complex

Blood

Volumn 121, Issue 8, 2013, Pages 1413-1421

  Gao, Chong ^a   Dimitrov, Todor ^a   Yong, Kol Jia ^b   Tatetsu, Hiro ^a   Jeong, Ha Won ^a   Luo, Hongbo R ^a   Bradner, James E ^c   Tenen, Daniel G ^b,d   Chai, Li ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; ANTILEUKEMIC AGENT; HISTONE DEACETYLASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN INHIBITOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SALL4; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; AMINO ACID SEQUENCE; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DEATH; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; EPIGENETICS; HUMAN; HUMAN CELL; IN VIVO STUDY; LEUKEMIA CELL; LEUKEMOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING;

EID: 84874403639     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-04-424275     Document Type: Article

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