메뉴 건너뛰기




Volumn 19, Issue 3, 2013, Pages 281-288

Glutamate gene polymorphisms predict brain volumes in multiple sclerosis

Author keywords

atrophy; endophenotyping; genetics; glutamate; MRI; Multiple sclerosis; single nucleotide polymorphisms; white matter

Indexed keywords

GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A;

EID: 84874394909     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458512454345     Document Type: Article
Times cited : (17)

References (45)
  • 1
    • 80051684615 scopus 로고    scopus 로고
    • Genetic risk and a primary role for cell-mediate immune mechanisms in multiple sclerosis
    • Sawcer S, et al. Genetic risk and a primary role for cell-mediate immune mechanisms in multiple sclerosis. Nature. 2011 ; 476: 214-219
    • (2011) Nature , vol.476 , pp. 214-219
    • Sawcer, S.1
  • 2
    • 67649876123 scopus 로고    scopus 로고
    • Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
    • De Jager PL, Jia X, Wang J, et al. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet. 2009 ; 41: 776-782
    • (2009) Nat Genet , vol.41 , pp. 776-782
    • De Jager, P.L.1    Jia, X.2    Wang, J.3
  • 3
    • 58949099391 scopus 로고    scopus 로고
    • Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis
    • Baranzini SE, Wang J, Gibson RA, et al. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet. 2009 ; 18: 767-778
    • (2009) Hum Mol Genet , vol.18 , pp. 767-778
    • Baranzini, S.E.1    Wang, J.2    Gibson, R.A.3
  • 4
    • 58149122959 scopus 로고    scopus 로고
    • The complex genetics of multiple sclerosis: Pitfalls and prospects
    • Sawcer S. The complex genetics of multiple sclerosis: Pitfalls and prospects. Brain. 2008 ; 131: 3118-3131
    • (2008) Brain , vol.131 , pp. 3118-3131
    • Sawcer, S.1
  • 5
    • 78649523088 scopus 로고    scopus 로고
    • SNP selection in genome-wide and candidate gene studies via penalized logistic regression
    • Ayers KL, Cordell HJ. SNP selection in genome-wide and candidate gene studies via penalized logistic regression. Genet Epidemiol. 2010 ; 34: 879-891
    • (2010) Genet Epidemiol , vol.34 , pp. 879-891
    • Ayers, K.L.1    Cordell, H.J.2
  • 6
    • 78751507648 scopus 로고    scopus 로고
    • Mining gold dust under the genome wide significance level: A two-stage approach to analysis of GWAS
    • Shi G, Boerwinkle E, Morrison AC, et al. Mining gold dust under the genome wide significance level: A two-stage approach to analysis of GWAS. Genet Epidemiol. 2011 ; 35: 111-118
    • (2011) Genet Epidemiol , vol.35 , pp. 111-118
    • Shi, G.1    Boerwinkle, E.2    Morrison, A.C.3
  • 7
    • 77956215911 scopus 로고    scopus 로고
    • Discovering genetic associations with high-dimensional neuroimaging phenotypes: A sparse reduced-rank regression approach
    • Vounou M, Nichols TE, Montana G. Discovering genetic associations with high-dimensional neuroimaging phenotypes: A sparse reduced-rank regression approach. Neuroimage. 2010 ; 53: 1147-1159
    • (2010) Neuroimage , vol.53 , pp. 1147-1159
    • Vounou, M.1    Nichols, T.E.2    Montana, G.3
  • 8
    • 0042266373 scopus 로고    scopus 로고
    • Altered expression patterns of group i and II metabotropic glutamate receptors in multiple sclerosis
    • Geurts JJ, Wolswijk G, Bo L, et al. Altered expression patterns of group I and II metabotropic glutamate receptors in multiple sclerosis. Brain. 2003 ; 126: 1755-1766
    • (2003) Brain , vol.126 , pp. 1755-1766
    • Geurts, J.J.1    Wolswijk, G.2    Bo, L.3
  • 9
    • 10344234219 scopus 로고    scopus 로고
    • Expression patterns of Group III metabotropic glutamate receptors mGluR4 and mGluR8 in multiple sclerosis lesions
    • Geurts JJ, Wolswijk G, Bo L, et al. Expression patterns of Group III metabotropic glutamate receptors mGluR4 and mGluR8 in multiple sclerosis lesions. J Neuroimmunol. 2005 ; 158: 182-190
    • (2005) J Neuroimmunol , vol.158 , pp. 182-190
    • Geurts, J.J.1    Wolswijk, G.2    Bo, L.3
  • 10
    • 77956369535 scopus 로고    scopus 로고
    • Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis
    • Baranzini SE, Srinivasan R, Khankhanian P, et al. Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis. Brain. 2010 ; 133: 2603-2611
    • (2010) Brain , vol.133 , pp. 2603-2611
    • Baranzini, S.E.1    Srinivasan, R.2    Khankhanian, P.3
  • 11
    • 28544436950 scopus 로고    scopus 로고
    • Diagnostic criteria for multiple sclerosis: 2005 revisions to the 'McDonald Criteria'
    • Polman CH, Reingold SC, Edan G, et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the 'McDonald Criteria'. Ann Neurol. 2005 ; 58: 840-846
    • (2005) Ann Neurol , vol.58 , pp. 840-846
    • Polman, C.H.1    Reingold, S.C.2    Edan, G.3
  • 12
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
    • Kurtzke JF. Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology. 1983 ; 33: 1444-1452
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 13
    • 0036742197 scopus 로고    scopus 로고
    • Accurate, robust, and automated longitudinal and cross-sectional brain change analysis
    • Smith SM, Zhang Y, Jenkinson M, et al. Accurate, robust, and automated longitudinal and cross-sectional brain change analysis. Neuroimage. 2002 ; 17: 479-489
    • (2002) Neuroimage , vol.17 , pp. 479-489
    • Smith, S.M.1    Zhang, Y.2    Jenkinson, M.3
  • 14
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, et al. PLINK: A tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007 ; 81: 559-575
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3
  • 15
    • 58849146101 scopus 로고    scopus 로고
    • Genotype- phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRI measures
    • Okuda DT, Srinivasan R, Oksenberg JR, et al. Genotype- phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRI measures. Brain. 2009 ; 132: 250-259
    • (2009) Brain , vol.132 , pp. 250-259
    • Okuda, D.T.1    Srinivasan, R.2    Oksenberg, J.R.3
  • 16
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: A practical and powerful approach to multiple testing. J Royal Statist Soc B. 1995 ; 57: 289-300
    • (1995) J Royal Statist Soc B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 17
    • 0035733108 scopus 로고    scopus 로고
    • The control of the false discovery rate in multiple testing under dependency
    • Benjamini Y, Yekutieli D. The control of the false discovery rate in multiple testing under dependency. Ann Statist. 2001 ; 29: 1165-1188
    • (2001) Ann Statist , vol.29 , pp. 1165-1188
    • Benjamini, Y.1    Yekutieli, D.2
  • 18
    • 0030196364 scopus 로고    scopus 로고
    • Stacked regressions
    • Breiman L. Stacked regressions. Machine Learn. 1996 ; 24: 49-64
    • (1996) Machine Learn , vol.24 , pp. 49-64
    • Breiman, L.1
  • 19
  • 20
    • 85194972808 scopus 로고    scopus 로고
    • Regression shrinkage and selection via the Lasso
    • Tibshirani R. Regression shrinkage and selection via the Lasso. J Royal Statist Soc B. 1996 ; 58: 267-288
    • (1996) J Royal Statist Soc B , vol.58 , pp. 267-288
    • Tibshirani, R.1
  • 21
    • 70449725209 scopus 로고    scopus 로고
    • Epigenetic mechanisms in neurological diseases: Genes, syndromes, and therapies
    • Urdinguio RG, Sanchez-Mut JV, Esteller M. Epigenetic mechanisms in neurological diseases: Genes, syndromes, and therapies. Lancet Neurol. 2009 ; 8: 1056-1072
    • (2009) Lancet Neurol , vol.8 , pp. 1056-1072
    • Urdinguio, R.G.1    Sanchez-Mut, J.V.2    Esteller, M.3
  • 22
    • 77953354132 scopus 로고    scopus 로고
    • Multiple sclerosis, vitamin D, and HLA-DRB1*15
    • Handunnetthi L, Ramagopalan SV, Ebers GC. Multiple sclerosis, vitamin D, and HLA-DRB1*15. Neurology. 2010 ; 74: 1905-1910
    • (2010) Neurology , vol.74 , pp. 1905-1910
    • Handunnetthi, L.1    Ramagopalan, S.V.2    Ebers, G.C.3
  • 23
    • 71849098862 scopus 로고    scopus 로고
    • Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: A weighted genetic risk score
    • De Jager PL, Chibnik LB, Cui J, et al. Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: A weighted genetic risk score. Lancet Neurol. 2009 ; 8: 1111-1119
    • (2009) Lancet Neurol , vol.8 , pp. 1111-1119
    • De Jager, P.L.1    Chibnik, L.B.2    Cui, J.3
  • 24
    • 0035171038 scopus 로고    scopus 로고
    • Hypointense lesions on T1-weighted spin-echo magnetic resonance imaging: Relation to clinical characteristics in subgroups of patients with multiple sclerosis
    • Van Walderveen MA, Lycklama ANG, Ader HJ, et al. Hypointense lesions on T1-weighted spin-echo magnetic resonance imaging: Relation to clinical characteristics in subgroups of patients with multiple sclerosis. Arch Neurol. 2001 ; 58: 76-81
    • (2001) Arch Neurol , vol.58 , pp. 76-81
    • Van Walderveen, M.A.1    Lycklama, A.N.G.2    Ader, H.J.3
  • 25
    • 0041522756 scopus 로고    scopus 로고
    • Remyelinated lesions in multiple sclerosis: Magnetic resonance image appearance
    • Barkhof F, Bruck W, de Groot CJ, et al. Remyelinated lesions in multiple sclerosis: Magnetic resonance image appearance. Arch Neurol. 2003 ; 60: 1073-1081
    • (2003) Arch Neurol , vol.60 , pp. 1073-1081
    • Barkhof, F.1    Bruck, W.2    De Groot, C.J.3
  • 26
    • 54849431166 scopus 로고    scopus 로고
    • Gray matter atrophy in multiple sclerosis: A longitudinal study
    • Fisher E, Lee JC, Nakamura K, Rudick RA. Gray matter atrophy in multiple sclerosis: A longitudinal study. Ann Neurol. 2008 ; 64: 255-265
    • (2008) Ann Neurol , vol.64 , pp. 255-265
    • Fisher, E.1    Lee, J.C.2    Nakamura, K.3    Rudick, R.A.4
  • 27
    • 34248680532 scopus 로고    scopus 로고
    • HLA-DRB1*1501, -DQB1*0301, -DQB1*0302, -DQB1*0602, and -DQB1*0603 alleles are associated with more severe disease outcome on MRI in patients with multiple sclerosis
    • Zivadinov R, Uxa L, Bratina A, et al. HLA-DRB1*1501, -DQB1*0301, -DQB1*0302, -DQB1*0602, and -DQB1*0603 alleles are associated with more severe disease outcome on MRI in patients with multiple sclerosis. Int Rev Neurobiol. 2007 ; 79: 521-535
    • (2007) Int Rev Neurobiol , vol.79 , pp. 521-535
    • Zivadinov, R.1    Uxa, L.2    Bratina, A.3
  • 28
    • 73549090822 scopus 로고    scopus 로고
    • HLA-DRB1*1501 and spinal cord magnetic resonance imaging lesions in multiple sclerosis
    • Sombekke MH, Lukas C, Crusius JB, et al. HLA-DRB1*1501 and spinal cord magnetic resonance imaging lesions in multiple sclerosis. Arch Neurol. 2009 ; 66: 1531-1536
    • (2009) Arch Neurol , vol.66 , pp. 1531-1536
    • Sombekke, M.H.1    Lukas, C.2    Crusius, J.B.3
  • 29
    • 65549084289 scopus 로고    scopus 로고
    • Pathway and network-based analysis of genome-wide association studies in multiple sclerosis
    • Baranzini SE, Galwey NW, Wang J, et al. Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet. 2009 ; 18: 2078-2090
    • (2009) Hum Mol Genet , vol.18 , pp. 2078-2090
    • Baranzini, S.E.1    Galwey, N.W.2    Wang, J.3
  • 30
    • 84856108049 scopus 로고    scopus 로고
    • Alzheimer's Disease Neuroimaging Initiative. Sparse reduced-rank regression detects genetic associations with voxel-wise longitudinal phenotypes in Alzheimer's disease
    • Vounou M, Janousova E, Wolz R, et al. Alzheimer's Disease Neuroimaging Initiative. Sparse reduced-rank regression detects genetic associations with voxel-wise longitudinal phenotypes in Alzheimer's disease. Neuroimage. 2012 ; 60: 700-716
    • (2012) Neuroimage , vol.60 , pp. 700-716
    • Vounou, M.1    Janousova, E.2    Wolz, R.3
  • 31
    • 80051469284 scopus 로고    scopus 로고
    • No influence on disease progression of non-HLA susceptibility genes in MS
    • Lundström W, Greiner E, Lundmark F, et al. No influence on disease progression of non-HLA susceptibility genes in MS. J Neuroimmunol. 2011 ; 237: 98-100
    • (2011) J Neuroimmunol , vol.237 , pp. 98-100
    • Lundström, W.1    Greiner, E.2    Lundmark, F.3
  • 32
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi DW. Glutamate neurotoxicity and diseases of the nervous system. Neuron. 1988 ; 1: 623-634
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 33
    • 33644797572 scopus 로고    scopus 로고
    • Glutamate-mediated glial injury: Mechanisms and clinical importance
    • Matute C, Domercq M, Sanchez-Gomez MV.. Glutamate-mediated glial injury: Mechanisms and clinical importance. Glia. 2006 ; 53: 212-224
    • (2006) Glia , vol.53 , pp. 212-224
    • Matute, C.1    Domercq, M.2    Sanchez-Gomez, M.V.3
  • 34
    • 27444432230 scopus 로고    scopus 로고
    • Excitotoxic oligodendrocyte death and axonal damage induced by glutamate transporter inhibition
    • Domercq M, Etxebarria E, Perez-Samartin A, et al. Excitotoxic oligodendrocyte death and axonal damage induced by glutamate transporter inhibition. Glia. 2005 ; 52: 36-46
    • (2005) Glia , vol.52 , pp. 36-46
    • Domercq, M.1    Etxebarria, E.2    Perez-Samartin, A.3
  • 36
    • 18744407587 scopus 로고    scopus 로고
    • Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T
    • Srinivasan R, Sailasuta N, Hurd R, et al. Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T. Brain. 2005 ; 128: 1016-1025
    • (2005) Brain , vol.128 , pp. 1016-1025
    • Srinivasan, R.1    Sailasuta, N.2    Hurd, R.3
  • 37
    • 29144508718 scopus 로고    scopus 로고
    • Increased expression and function of glutamate transporters in multiple sclerosis
    • Vallejo-Illarramendi A, Domercq M, Perez-Cerda F, et al. Increased expression and function of glutamate transporters in multiple sclerosis. Neurobiol Dis. 2006 ; 21: 154-164
    • (2006) Neurobiol Dis , vol.21 , pp. 154-164
    • Vallejo-Illarramendi, A.1    Domercq, M.2    Perez-Cerda, F.3
  • 38
    • 42049123242 scopus 로고    scopus 로고
    • Association of an EAAT2 polymorphism with higher glutamate concentration in relapsing multiple sclerosis
    • Pampliega O, Domercq M, Villoslada P, et al. Association of an EAAT2 polymorphism with higher glutamate concentration in relapsing multiple sclerosis. J Neuroimmunol. 2008 ; 195: 194-198
    • (2008) J Neuroimmunol , vol.195 , pp. 194-198
    • Pampliega, O.1    Domercq, M.2    Villoslada, P.3
  • 39
    • 0034911054 scopus 로고    scopus 로고
    • Multiple sclerosis: Altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage
    • Werner P, Pitt D, Raine CS. Multiple sclerosis: Altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage. Ann Neurol. 2001 ; 50: 169-180
    • (2001) Ann Neurol , vol.50 , pp. 169-180
    • Werner, P.1    Pitt, D.2    Raine, C.S.3
  • 40
    • 77956122814 scopus 로고    scopus 로고
    • Excitatory glycine responses of CNS myelin mediated by NR1/NR3 'NMDA' receptor subunits
    • Pina-Crespo JC, Talantova M, Micu I, et al. Excitatory glycine responses of CNS myelin mediated by NR1/NR3 'NMDA' receptor subunits. J Neurosci. 2010 ; 30: 11501-11505
    • (2010) J Neurosci , vol.30 , pp. 11501-11505
    • Pina-Crespo, J.C.1    Talantova, M.2    Micu, I.3
  • 41
    • 74249090672 scopus 로고    scopus 로고
    • Role of prions in neuroprotection and neurodegeneration: A mechanism involving glutamate receptors?
    • Zamponi GW, Stys PK. Role of prions in neuroprotection and neurodegeneration: A mechanism involving glutamate receptors?. Prion. 2009 ; 3: 187-189
    • (2009) Prion , vol.3 , pp. 187-189
    • Zamponi, G.W.1    Stys, P.K.2
  • 42
    • 33644520285 scopus 로고    scopus 로고
    • NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia
    • Micu I, Jiang Q, Coderre E, et al. NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia. Nature. 2006 ; 439: 988-992
    • (2006) Nature , vol.439 , pp. 988-992
    • Micu, I.1    Jiang, Q.2    Coderre, E.3
  • 43
    • 59949106172 scopus 로고    scopus 로고
    • Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis
    • Trapp BD, Stys PK. Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis. Lancet Neurol. 2009 ; 8: 280-291
    • (2009) Lancet Neurol , vol.8 , pp. 280-291
    • Trapp, B.D.1    Stys, P.K.2
  • 44
    • 29244483141 scopus 로고    scopus 로고
    • NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury
    • Salter MG, Fern R. NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury. Nature. 2005 ; 438: 1167-1171
    • (2005) Nature , vol.438 , pp. 1167-1171
    • Salter, M.G.1    Fern, R.2
  • 45
    • 84855991876 scopus 로고    scopus 로고
    • Non-coding RNAs with essential roles in neurodegenerative disorders
    • Salta E, de Strooper B. Non-coding RNAs with essential roles in neurodegenerative disorders. Lancet Neurol. 2012 ; 11: 189-200
    • (2012) Lancet Neurol , vol.11 , pp. 189-200
    • Salta, E.1    De Strooper, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.