Caspase-2 Is Upregulated after Sciatic Nerve Transection and Its Inhibition Protects Dorsal Root Ganglion Neurons from Apoptosis after Serum Withdrawal

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Vigneswara, Vasanthy ^a,b   Berry, Martin ^a,b   Logan, Ann ^a,b   Ahmed, Zubair ^a,b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b Neuregenix Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 2; CASPASE 3; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL LOSS; CELL NUCLEUS; CELL SURVIVAL; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; ENZYME INDUCTION; ENZYME LOCALIZATION; ENZYME REGULATION; FEMALE; GLIA CELL; IN VITRO STUDY; IN VIVO STUDY; NERVE FIBER TRANSECTION; NERVE TRANSECTION; NICK END LABELING; NONHUMAN; PROTEIN CLEAVAGE; RAT; SCIATIC NERVE TRANSECTION; SPINAL GANGLION; UPREGULATION;

ANIMALS; APOPTOSIS; CASPASE 2; CASPASE 3; CASPASE INHIBITORS; CELL NUCLEUS; CYTOSOL; FEMALE; GANGLIA, SPINAL; IN SITU NICK-END LABELING; NERVE REGENERATION; NEURONS; NEURONS, AFFERENT; RATS; RATS, SPRAGUE-DAWLEY; SCHWANN CELLS; SCIATIC NERVE; UP-REGULATION;

EID: 84874387178     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057861     Document Type: Article

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